Abstract Parkinson’s disease (PD) is a progressively debilitating neurodegenerative condition that leads to motor and cognitive dysfunction. At present, clinical treatment can only improve symptoms, but cannot effectively protect dopaminergic neurons. Several reports have demonstrated human umbilical cord mesenchymal stem cells (hucMSCs) afford neuroprotection, while their application limited because of uncontrollable differentiation other reasons. Stem communicate with through secreted...

Microglia-mediated inflammatory responses have been shown to play a crucial role in Parkinson's disease. In addition, exosomes derived from mesenchymal stem cells anti-inflammatory effects the treatment of variety diseases. However, whether they can protect neurons disease by inhibiting microglia-mediated is not yet known. this study, were isolated human umbilical cord and injected into 6-hydroxydopamine-induced rat model We found that through tail vein lateral ventricle absorbed...

Abstract Background Wheat ( Triticum aestivum L.) is a significant cereal crop that plays vital role in global food production. To expedite the breeding of wheat cultivars with high protein quality, it necessary to genetically analyze traits related quality. A genome-wide association study (GWAS) was conducted identify genomic regions responsible for quality winter wheat. Results Six were evaluated across two locations and years total 341 accessions. Utilizing 40 K SNP array, GWAS identified...

Parkinson's disease (PD) is a progressive neurological disorder characterized by loss of neurons that synthesize dopamine, and subsequent impaired movement. Umbilical cord mesenchymal stem cells (UC-MSCs) exerted neuroprotection effects in rodent model PD. However, the mechanism underlying UC-MSC-generated was not fully elucidated. In present study, we found intranasal administration UC-MSCs significantly alleviated locomotor deficits rescued dopaminergic inhibiting neuroinflammation PD...

Recently, replacing chemical fertilizers with straw returning and new has received considerable attention in the agricultural sector, as it is believed to increase rice yield improve soil properties. However, less known about growth properties paddy fields addition of different fertilizers. Thus, this paper, we investigated effects fertilizer treatments, including no fertilization (CK), optimized based on medium recommended amount (OF), 4.50 Mg ha−1 (SF), 0.59 slow-release (SRF), 0.60...

Endovascular treatment has achieved great progress over the past few decades, providing multiple options for of intracranial aneurysms (IAs). In present era flow diverters (FDs), optimum endovascular management unruptured IAs amenable to both stent-assisted coiling (SAC) and FDs remains be determined. Therefore, our study aimed compare midterm outcomes costs Pipeline embolization device (PED) alone versus Atlas SAC saccular anterior circulation aneurysms. This is a retrospective cohort in...

Starch is the main component of wheat (Triticum aestivum L.) flour, and its quality directly affects processing final product. To investigate genetic basis starch, this study assessed starch traits 341 winter varieties/lines grown in Emin Qitai during years 2019-2020 2020-2021. A genome-wide association was conducted with genotype data obtained from 40K breeding chips using mixed linear model. Wheat exhibited coefficients variation ranging 1.43% to 23.66% broad-sense heritabilities between...

Alzheimer's disease (AD), the most common cause of dementia, is a neurodegenerative disorder characterized by amyloid plaque accumulations, intracellular tangles and neuronal loss in certain brain regions. It has been shown that disturbance normal iron metabolism contributes to pathophysiology AD. However, mechanism underlying abnormal load AD patients unclear. The frontal cortex, an important structure for executive function, one regions affected We investigated beneficial effects active...

Background: Hypertension is a major risk factor for cardiovascular diseases and the leading cause of mortality worldwide. Despite availability antihypertensive drugs, alternative treatments are needed due to adverse events associated with their use. Previous studies have shown that SABP, combination aqueous active metabolites Salvia Miltiorrhiza Bunge DSS, Sal-A, Sal-B PAL, has significant effect. However, underlying mechanisms remain unknown. Objective: This study aimed determine effects...

Objective: To investigate the predictive factors for bronchitis obliterans in refractory Mycoplasma pneumoniae pneumonia (RMPP). Methods: A restrospective case summary was conducted 230 patients with RMPP admitted to Department of No.2 Respiratory Medicine Beijing Children's Hospital, Capital Medical University from January 2013 June 2017 were recruited. Clinical data, laboratory results, imaging results and follow-up data collected. Based on bronchoscopy findings 1 year after discharge, all...

Salvia miltiorrhiza (SM) contains four major aqueous active ingredients, which have been isolated, purified and identified as danshensu (DSS), salvianolic acid A (Sal-A), B (Sal-B) protocatechuic aldehyde (PAL), mixture of these ingredients is called SABP. Although extract from has traditionally used to treat cardiovascular diseases, the efficacy function optimal ratio SABP in preventing treating diseases remain unknown. This study aims explore antiinflammatory mechanisms underlying...

Summary. A rare case of pyoderma gangraenosum caused by Rhizopus arrhizus is reported. The patient, a 50‐year‐old male farmer, was admitted to hospital complaining gangrening and festering the right upper arm with severe pain for nearly 2 months. lesion found on inside arm. central skin part became black dry gangrenous, periphery deeply ulcerated yellow‐green pus. necrotic crust, biceps, triceps vessels inherited histopathologically proven fungal infection. fungus isolated identified as ....

Introduction: Fertilizer application above plant nitrogen (N) requirements, leading to N use inefficiency, has become the primary source of surplus, posing nonpoint pollution threats. Chao Lake received loadings, primarily from agroecosystem that surrounds it. Based on 10 years field monitoring and experiment, this study used optimum fertilizer rates (30% reduction) evaluate efficiency (NUE) export in watershed paddy rice-wheat rotational farming. Methods: Five treatments were tested,...

ISHS I International Symposium on Litchi and Longan THE EFFECT OF SYNTHETIC AUXINS 2,4,5-TP AND 3,5,6-TPA ON YIELD FRUIT SIZE YOUNG ‘FEI ZI XIAO’ ‘HEI YE’ LITCHI TREES IN GUANGXI PROVINCE, CHINA

Heterosis is a promising approach to increase wheat yield from limited planting area. In this study, fine quality restorer line 99AR144-1 and three stable male sterile lines, AL18A, AL36A AL20A, were assigned as female, respectively. Seeds of the lines mixed according different proportions then planted at an experimental farm Xinjiang Academy Agri- Reclamation Sciences 2013 2016. When sowing ratios combinations 2 (AL36A × 99AR144- 1) 3 (AL20A 99AR144-1) 6 8%, seed production yields higher...

AMA Huang R, Zhuang Y, Chang Li L, Xu H. A retrospective analysis of comorbidities in patients with psoriasis at a single centre. Advances Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2024;41(2):164-172. doi:10.5114/ada.2024.139123. APA Huang, R., Zhuang, Y., Chang, Li, L., & Xu, (2024). Alergologii, 41(2), 164-172. https://doi.org/10.5114/ada.2024.139123 Chicago Rui, Yi Yuan Lin-Feng Hong-Jun Xu. 2024. "A centre". Alergologii 41 (2): Harvard pp.164-172. MLA Rui et al....

Objective: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with symptoms including tremor and bradykinesia, while traditional dopamine replacement therapy hypothalamic deep brain stimulation can temporarily relieve patients’ symptoms, they cannot cure the disease. Hence, discovering new methods crucial to designing more effective therapeutic approaches address condition. In our previous study, we found that exosomes (Exos) derived from human umbilical cord mesenchymal...

Abstract The red algae Gracilariopsis lemaneiformis is extensively cultivated at high densities, leading to significant increases in regional seawater pH due its photosynthetic removal of inorganic carbon. We conducted a study on G. cultured under various conditions (normal pH, 9.3, and 9.6) light levels (dark 100 μmol photons m −2 s −1 ) investigate how environments affect the metabolic processes . did not directly damage reactions or Calvin cycle. Instead, observed reduction rates was...

In order to understand the difference of quality for Chinese and CIMMYT wheat varieties (lines), we selected 153 germplasm from both China explore contribution relationship different allelic variation combinations through genotyping phenotyping, including grain hardness, polyphenol oxidase (PPO) activity, lipoxygenase (LOX) yellow pigment (YP) content protein content. terms flour milling quality, were mainly carrying Pina-D1a/Pinb-D1b, accounting 32.0% total tested varieties, while lines...