- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- RNA Interference and Gene Delivery
- Induction Heating and Inverter Technology
- Cancer Mechanisms and Therapy
- Electric Motor Design and Analysis
- Cancer-related molecular mechanisms research
- Fire effects on concrete materials
- Electric Power Systems and Control
- RNA Research and Splicing
- Building materials and conservation
- Aeolian processes and effects
- Signaling Pathways in Disease
- interferon and immune responses
- Liver physiology and pathology
- Innovative concrete reinforcement materials
- Cancer Immunotherapy and Biomarkers
- Concrete Corrosion and Durability
- Structural Behavior of Reinforced Concrete
- Organ Transplantation Techniques and Outcomes
- Concrete and Cement Materials Research
- Phytochemistry and biological activity of medicinal plants
- Advanced biosensing and bioanalysis techniques
- Liver Disease Diagnosis and Treatment
- Drug Transport and Resistance Mechanisms
Shandong Normal University
2024
Imperial College London
2024
Leibniz-Institute for New Materials
2024
National Renewable Energy Laboratory
2024
University of Colorado Boulder
2024
Environmental Energy & Engineering
2024
The University of Adelaide
2024
Tianjin Medical University
2022-2023
Nankai University
2022-2023
Qilu Hospital of Shandong University
2023
Finding a drug for early intervention in the hepatic fibrosis process has important clinical significance. Previous studies have suggested SUMOylation as potential target fibrosis. However, role of SAE1, marker SUMOylation, is unknown. Additionally, whether ginkgolic acid (GA), inhibitor, inhibits by inhibiting SUMO1-activating enzyme subunit 1 (SAE1) should be further investigated.
Neovascular ocular diseases (NODs) represent the leading cause of visual impairment globally. Despite significant advances in anti-angiogenic therapies targeting vascular endothelial growth factor (VEGF), persistent challenges remain prevalent. As a proof-of-concept study, we herein demonstrate effectiveness targeted degradation VEGF with bispecific aptamer-based lysosome-targeting chimeras (referred to as VED-LYTACs).
Transplant oncology is a newly emerging discipline integrating oncology, transplant medicine, and surgery has brought malignancy treatment into new era via transplantation. In this context, obtaining drug with both immunosuppressive antitumor effects can take account the dual needs of preventing rejection tumor recurrence in liver transplantation patients malignancies. Capecitabine (CAP), classic drug, been shown to induce reactive oxygen species (ROS) production apoptosis cells. Meanwhile,...
Biliary complications are currently one of the leading causes liver failure and patient death after transplantation need to be solved urgently. ischemia-reperfusion injury (IRI) is important biliary complications. IL-22 has a protective effect on hepatitis diseases, its safety efficacy in treatment have also been proved human clinical experiments. Furthermore, multiple studies confirmed that promotes proliferation repair epithelial cells various organs. Still, function bile duct not...
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In this investigation, in order to understand deterioration processes of concrete from surfaces interiors under temperature gradient effects, 150mm cubic specimens were heated without temperature-rising stages at 800° for 20min, 40min, 60min, 90min and 120min then cooled with running water. For the purpose evaluating characteristics concrete, compressive strengths cracking conditions specimens, microstructural morphologies constituents, as well dehydration degrees matrix determined. Results...
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with high morbidity and mortality. Therefore, finding new diagnostic therapeutic targets vital for HCC patients. Recent studies have shown that dysregulation RNA-binding proteins often associated cancer progression. Several reported protein SSB can promote occurrence progression linked to tumor epithelial-mesenchymal transition (EMT), which could be a marker target. However, expression function in remain elucidated....