Zhixin Zhang

ORCID: 0000-0002-9219-5356
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About
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Research Areas
  • Reconstructive Surgery and Microvascular Techniques
  • Nerve Injury and Rehabilitation
  • Orthopedic Surgery and Rehabilitation
  • Bone fractures and treatments
  • Peripheral Nerve Disorders
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease and Transplantation
  • RNA modifications and cancer
  • Nerve injury and regeneration
  • Anesthesia and Sedative Agents
  • Cytomegalovirus and herpesvirus research
  • Spinal Dysraphism and Malformations
  • Spinal Cord Injury Research
  • Reconstructive Facial Surgery Techniques
  • Ferroptosis and cancer prognosis
  • Prosthetics and Rehabilitation Robotics
  • Surgical site infection prevention
  • Pelvic floor disorders treatments
  • CNS Lymphoma Diagnosis and Treatment
  • Biological and pharmacological studies of plants
  • Medical Malpractice and Liability Issues
  • Circular RNAs in diseases
  • Phytochemistry and biological activity of medicinal plants
  • MRI in cancer diagnosis
  • Cancer-related molecular mechanisms research

Changzhou Third People's Hospital
2009-2024

Tianjin Medical University
2021-2023

Nanyang Institute of Technology
2022

Henan University
2022

Tianjin First Center Hospital
2022

Jilin University
2002-2020

Creative Commons
2020

First Hospital of Jilin University
2002-2020

National Natural Science Foundation of China
2020

National Center for Clinical Laboratories
2020

OBJECTIVE Spontaneous paralysis from hourglass-like fascicular constriction of peripheral nerves is rare, its clinical manifestations are not well documented, and pathogenesis remains unknown. The unclear origin this disorder difficulty in diagnosis result uncertain management. authors sought to gain a more thorough understanding condition through describing the anatomy, features, etiology, treatment constriction. METHODS retrospectively reviewed 20 patients (22 nerves) with patients’...

10.3171/2018.8.jns18419 article EN Journal of neurosurgery 2019-02-27

Abstract Background Ciprofol is a promising sedative. This study aims to explore the median effective dose (ED50) of ciprofol in inhibiting responses fiberoptic bronchoscopy patients with pulmonary tuberculosis (PTB) different genders and ages when combined 0.15 μg/kg sufentanil, evaluate its efficacy safety, providing reference for rational use clinical practice. Methods PTB who underwent examination treatment at The Third People’s Hospital Changzhou between May 2023 June were selected...

10.1186/s12871-024-02583-w article EN cc-by BMC Anesthesiology 2024-06-04

Long non-coding RNAs (lncRNAs) are associated with occurrence and development of tumors. Enhancer RNA (eRNA) is a special type lncRNAs produced from transcription enhancer elements. The function eRNAs in tumors have elicited significant attention recently. However, the clinical significance role hepatocellular carcinoma (HCC) has not been fully explored. current study sought to explore expression level prognostic value key HCC. Bioinformatics analyses were used levels HCC their correlation...

10.18632/aging.203593 article EN cc-by Aging 2021-10-04

Biliary complications are currently one of the leading causes liver failure and patient death after transplantation need to be solved urgently. ischemia-reperfusion injury (IRI) is important biliary complications. IL-22 has a protective effect on hepatitis diseases, its safety efficacy in treatment have also been proved human clinical experiments. Furthermore, multiple studies confirmed that promotes proliferation repair epithelial cells various organs. Still, function bile duct not...

10.1155/2022/9635075 article EN cc-by Oxidative Medicine and Cellular Longevity 2022-05-10

This study aimed to explore whether serum CXCL8 concentration can be used as a noninvasive marker of subclinical rejection (SCR) after pediatric liver transplantation (pLT).Firstly, RNA sequencing (RNA-seq) was performed on 22 protocol biopsy samples. Secondly, several experimental methods were verify the RNA-seq results. Finally, clinical data and samples 520 LT patients in Department Pediatric Transplantation Tianjin First Central Hospital from January 2018 December 2019 collected.RNA-seq...

10.1097/tp.0000000000004601 article EN Transplantation 2023-05-05

Abstract Purpose: The aim of the soft tissue reconstruction plantar forefoot should yield weight-bearing function and aesthetic contour, which poses a significant challenge for reconstructive surgeons to provide an appropriate flap according “like like” principle. Local flaps pedicled have been described small- medium-sized defects achieved optimal results. However, extensive is rarely investigated. In this study, we present our experience using free anterolateral thigh (ALT) in forefoot....

10.1097/md.0000000000020819 article EN cc-by-nc Medicine 2020-12-10

Biliary atresia (BA) is the most common indication for pediatric liver transplantation, and biliary stricture (BS) remains an Achilles’ heel living donor transplantation (LDLT). We investigated impact of different ischemia times on BS after LDLT in patients with BA. retrospectively analyzed (<18 y) BA who underwent between January 2016 December 2020. Cases hepatic artery thrombosis, bile leakage, early (<2 wk), death (<3 mo) were excluded. In all, 572 cases included. A total 26...

10.1097/lvt.0000000000000092 article EN Liver Transplantation 2023-02-07

Management of extensive bone and soft tissue defects, which occur after severe trauma lower extremities always lead to an unacceptable amputation in some cases, continues challenge reconstructive surgeons. When performing extremity amputation, preservation the knee joint has been put into a higher priority. The benefit below-knee over above-knee ones concentrates on more normal gait with less energy expenditure during ambulation when functioning is present.

10.1016/s1008-1275(08)60077-2 article EN cc-by-nc-nd Chinese Journal of Traumatology 2008-12-01

To explore a new method to treat brachial plexus root avulsion experimentally by reimplantation combined with transplantation of neural stem cells (NSCs) modified neurotrophin-3 gene (NT-3). The total RNA was extracted from neonatal rat striatum and the NT-3 cDNA obtained reverse transcription amplified polymerase chain reaction. transferred into NSCs via pLEGFP-C1, an expression plasmid vectors. untransfected NSCs, pLEGFP-C1 treated pLEGFP-C1-NT-3 were transplanted corresponding spinal cord...

10.1016/s1008-1275(08)60054-1 article EN cc-by-nc-nd Chinese Journal of Traumatology 2008-10-01

To analyze the coefficient of variation (CV) external quality assessment (EQA) in Chinese newborn screening (NBS) laboratories.EQA's robust CV was analyzed by Clinet-EQA evaluation system.Participating laboratories EQA program increased annually. There more than a 11-fold increase phenylalanine (Phe) and thyroid stimulating hormone (TSH). It has shown declining CV, which tended to level off recent years. The interquartile range (IQR) Phe TSH's decreased from 15.5% 1.5% 22.8% 1.8%,...

10.3390/ijns6020038 article EN cc-by International Journal of Neonatal Screening 2020-05-09

Abstract Background Posttransplant lymphoproliferative disease (PTLD) is a serious complication after pediatric liver transplantation (pLT), which may lead to death. 18 F‐FDG PET/CT rarely considered in PTLD pLT and lacks clear diagnostic guidelines, especially the differential diagnosis of nondestructive PTLD. The aim this study was find quantifiable index identify pLT. Methods This retrospective collected data patients who underwent pLT, postoperative lymph node biopsy, at Tianjin First...

10.1111/petr.14501 article EN Pediatric Transplantation 2023-03-11

Abstract Backgroud: Ciprofol is a promising sedative. At present, there were few clinical studies on the median effective dose (ED50) of ciprofol. The aim this study was to compare ED50 ciprofol for fiberoptic bronchoscopy in pulmonary tuberculosis (TB) patients different genders and ages. Methods: TB who underwent examination treatment at Third People’s Hospital Changzhou between May 2023 June selected, divided into four groups according stratified random method: Group N1 (non-elderly male...

10.21203/rs.3.rs-3122369/v1 preprint EN cc-by Research Square (Research Square) 2023-07-25

Objective To explore the application of anti skin grafting and two pedicled abdominal flap to repair whole hand degloving injury.Methods From June,2007 December,2013,20 cases injury graft,waste combined VSD vacuum suction fingers repair,postoperative activity,strength,degree sensory recovery function four standards,respectively.After doing comprehensive evaluation.Evaluation standard:excellent for 13-16,good 9-12 minutes,could be 5-8,difference 4 points.Results Excellent functional in 19...

10.3760/cma.j.issn.1001-2036.2014.05.014 article EN 2014-10-25

Objective To evaluate the therapeutic effect of in situ ulnar nerve decompression at cubital tunnel via a small incision assisted with electromyography localization and discuss surgical indications.Methods Twelve patients who were diagnosed idiopathic syndrome (CuTS) without intrinsic muscle atrophy elbow deformity involved study.Before operation, short-segment conduction test (SSCT) was carried out.The exact compression site determined by > 50%reduction amplitude or 0.5 ms lengthening...

10.3760/cma.j.issn.1005-054x.2011.02.013 article EN Zhonghua shouwaike zazhi 2011-04-10
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