A5024217463- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Transplantation: Methods and Outcomes
- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Hepatitis C virus research
- Congenital Anomalies and Fetal Surgery
- Liver Diseases and Immunity
- Pediatric Hepatobiliary Diseases and Treatments
- Parallel Computing and Optimization Techniques
- Distributed and Parallel Computing Systems
- Cytomegalovirus and herpesvirus research
- Meteorological Phenomena and Simulations
- Scientific Computing and Data Management
- Clinical Nutrition and Gastroenterology
- Algorithms and Data Compression
- Congenital Diaphragmatic Hernia Studies
- Climate variability and models
- Anomaly Detection Techniques and Applications
- Computer Graphics and Visualization Techniques
- Neonatal Health and Biochemistry
- Tropical and Extratropical Cyclones Research
- Metabolism and Genetic Disorders
Tianjin First Center Hospital
2016-2025
Tianjin Medical University
2016-2025
Harbin Engineering University
2023-2025
Tianjin University
2003-2024
Tianjin Medical University General Hospital
2023
Tsinghua University
2019-2022
National Center For Child Health and Development
2021
Tianjin People's Hospital
2019-2020
Shandong University of Finance and Economics
2019
Civil Aviation University of China
2018
The incidence of graft fibrosis is elevated following pediatric liver transplantation (pLT) and influenced by cold ischemic time (CIT). Myosin light chain 9 (MYL9), a member the myosin family, could act on hepatic stellate cells (HSCs) induce transition to active phase. We hypothesized that injury stimulate MYL9 expression lead fibrosis. tested hypothesis analyzing multi-omics data from human protocol biopsy samples 2 years after transplant, performing rat LT with different CIT conducting in...
Post-liver transplantation-Burkitt lymphoma (PLT-BL) is an aggressive and life-threatening complication after pediatric liver transplantation. The research on the disease characteristics, treatment, prognosis of PLT-BL limited. A retrospective, observational study was performed to analyze outcomes in 12 transplant (LT) recipients diagnosed with PLT-BL. medium time from transplantation diagnosis 32.71 months (range, 25.78-37.85 months). All patients (100%) tested positive for EBV viremia at...
ABSTRACT Background A growing number of studies indicate that acute kidney injury (AKI) and the pattern recovery after are associated with poor outcomes for grafts long‐term renal function liver transplantation (LT). However, few systematic have been conducted on pediatric (PLT) population. Materials Methods In this single‐centered retrospective observational study, according to AKI degree whether was persistent, patients were divided into three groups: non‐AKI/stage 1 AKI, stage 2/3...
Background. Optimizing the immunosuppressive regimen is essential to improve long-term outcomes of pediatric liver transplant recipients. Methods. We conducted a prospective, randomized, open-label study compare safety and efficacy 2 treatment approaches during transplantation: tacrolimus monotherapy following basiliximab induction (the group) dual plus steroids control group). A total 150 patients were enrolled, with 75 allocated each group. Results. In both groups, recipients achieved...
Abstract Tropical cyclones (TCs), especially landfalling intense storms often pose serious threats to life and property in coastal areas. Although TC track forecast skill has been improved the past decades, progress of advancing intensity lags that forecast. One possible limiting factor is absence ocean surface waves systems. To better represent interaction underlying ocean, a regional atmosphere‐ocean‐wave coupled model employed this study. Twenty‐one TCs whole year 2013 are retrospectively...
The lack of age- and size-matched organs result in higher waiting list mortality pediatric recipients than adults. Organs from deceased newborns infants are a valuable source to increase donor pool liver transplantation. However, the feasibility safety using neonatal donors have not been well evaluated.From 2014 2016, 48 transplantations with age younger 1 year old our center were enrolled this study. divided into three groups based on (<1 month, month ≤ <3 months, 3 months <1 year)....
This retrospective study was conducted to evaluate the effect of a new, modified open surgery technique on catheter-related malfunction.During period from January 1997 June 2009, 216 patients received initial peritoneal catheters. For present study, were divided into four groups according catheter types and techniques: TO-S: traditional surgery, straight Tenckhoff TO-C: coiled TO-SN: swan-neck MO-S: The characterized by low incision site, short intra-abdominal segment an additional upward...
The experience of using pediatric donors in split liver transplant is exceedingly rare. We aim to investigate the outcomes recipients receiving grafts. Sixteen grafts from 8 < 7 years were enrolled. donor and recipient characteristics, perioperative course, postoperative complications, graft survival rates evaluated. mean follow-up time was 8.0 ± 2.3 months. 100%. function remained normal range at end all recipients. No life-threatening complications seen these recipients, only...
This study aimed to explore whether serum CXCL8 concentration can be used as a noninvasive marker of subclinical rejection (SCR) after pediatric liver transplantation (pLT).Firstly, RNA sequencing (RNA-seq) was performed on 22 protocol biopsy samples. Secondly, several experimental methods were verify the RNA-seq results. Finally, clinical data and samples 520 LT patients in Department Pediatric Transplantation Tianjin First Central Hospital from January 2018 December 2019 collected.RNA-seq...
BACKGROUND:Pediatric liver transplantation is used to treat children with end-stage disease. This study explored the research hotspots and bibliometric characteristics of pediatric through a variety analysis software. We conducted hotspot help determine important directions for future scientific research. MATERIAL AND METHODS:The samples were articles related published in PubMed past 5 years. The high-frequency keywords are extracted by BICOMB software, then binary matrix common word...
Dynamic programming approach solves complex problems efficiently by breaking them down into simpler sub-problems, and is widely utilized in scientific computing. With the increasing data volume of applications development multi-core/multi-processor hardware technologies, it necessary to develop efficient techniques for parallelizing dynamic algorithms, particularly multilevel computing environment. The intrinsically strong dependency also makes difficult error-prone programmer write a...
The aim of this study was to analyze the incidence and risk factors de novo HBV infection in pediatric patients receiving living donor liver transplants (LDLT) from HBcAb-positive donors, explore its treatment strategies. data 101 recipients LDLT Tianjin First Central Hospital between September 2006 December 2012 were retrospectively analyzed. markers regularly tested before after surgery, including HBsAb, HBsAg, HBeAg, HBeAb, HBcAb. median follow-up period 25.6 months, during which eight...
The native liver of patients with maple syrup urine disease (MSUD) (1st recipients) can be used as a graft for non-MSUD end-stage (2nd recipients). This study aimed to demonstrate the optimal operational procedures and long-term outcomes 2nd recipients.Six recipients living donor domino transplantation (LD-DLT) (age: 42.5 [22-169] months at DLT) received from an MSUD patient our hospital between June 2014 April 2020. We reviewed after LD-DLT.The recipients' original diseases included biliary...
Donor shortage is an important limitation of liver transplantation (LT). Split (SLT) may increase the sources donors and reduce problem organ shortage. However, there are no standard criteria selection SLT donor, especially regarding donor age. We retrospectively analyzed clinical data children who received initial between January 2015 December 2021. Based on age donors, patients were divided into groups A (1-10 years old; n = 26), B (10-45 87), C (45-55 27). The short-term (<1 year after...