Huachun Pan

ORCID: 0000-0002-4132-0946
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About
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Research Areas
  • Probiotics and Fermented Foods
  • Gut microbiota and health
  • Cardiovascular Health and Disease Prevention
  • Cell death mechanisms and regulation
  • Cancer, Lipids, and Metabolism
  • Cerebrovascular and Carotid Artery Diseases
  • Nanoparticle-Based Drug Delivery
  • Animal Nutrition and Physiology
  • Infant Nutrition and Health
  • Blood Pressure and Hypertension Studies
  • Inflammasome and immune disorders
  • Nanoplatforms for cancer theranostics
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Extracellular vesicles in disease
  • Trace Elements in Health
  • Aldose Reductase and Taurine
  • Silk-based biomaterials and applications
  • NF-κB Signaling Pathways
  • Cardiac Ischemia and Reperfusion
  • Ferroptosis and cancer prognosis
  • Inflammatory Biomarkers in Disease Prognosis
  • Electrospun Nanofibers in Biomedical Applications
  • Cancer-related cognitive impairment studies
  • Environmental Toxicology and Ecotoxicology
  • Adipokines, Inflammation, and Metabolic Diseases

Huazhong Agricultural University
2020-2025

Renmin Hospital of Wuhan University
2024

Wuhan University
2024

Background Significant evidence suggests that asthma might originate from low-grade systemic inflammation. Previous studies have established a positive association between the immune-inflammation index (SII) and inflammation response (SIRI) levels risk of stroke. However, it remains unclear whether SII, SIRI prevalence stroke are related in individuals with asthma. Methods The present cross-sectional study used data National Health Nutrition Examination Survey (NHANES) conducted 1999 2018....

10.3389/fimmu.2023.1191130 article EN cc-by Frontiers in Immunology 2023-08-04

Ulcerative colitis (UC) is a chronic and progressive inflammatory gastrointestinal disease closely associated with gut microbiota dysbiosis metabolic homeostasis disruption. Although targeted microbial therapies are an emerging intervention strategy for bowel (IBD), the mechanisms by which specific probiotics, such as Lactobacillus fermentum 016 (LF), alleviate UC remain unclear. The current study evaluated effects of LF supplementation on health in basal model using C57BL/6 mice....

10.3390/nu17030452 article EN Nutrients 2025-01-26

Abstract Background Estimated pulse wave velocity (ePWV) has been proposed as a potential approach to estimate carotid-femoral velocity. However, the of ePWV in predicting all-cause mortality (ACM) and cardiovascular disease (CVM) general population is unclear. Methods We conducted prospective cohort study using data 33,930 adults (age ≥ 20 years) from National Health Nutrition Examination Survey (NHANES) 1999 2014 until end December 2019. The outcomes included ACM CVM. Survey-weighted Cox...

10.1186/s12889-024-18071-2 article EN cc-by BMC Public Health 2024-02-24

Background Estimated pulse wave velocity (ePWV) has been proposed as a potential alternative to carotid-femoral assess the degree of aortic stiffness, and may predict cardiovascular disease (CVD) outcomes mortality in general population. However, whether arterial stiffness estimated by ePWV predicts all-cause cause-specific patients with diabetes mellitus (DM) not reported. Methods This was prospective cohort study data from National Health Nutrition Examination Survey (NHANES) 1999 2014...

10.3389/fendo.2023.1145914 article EN cc-by Frontiers in Endocrinology 2023-03-08

Background Arterial stiffness is a significant determinant and evaluation of cardio-cerebrovascular disease all-cause mortality risk in the stroke population. Estimated pulse wave velocity (ePWV) well-established indirect measure arterial stiffness. We examined association ePWV with (CCD) population large sample US adults. Methods The study design was prospective cohort data from National Health Nutrition Examination Survey (NHANES) 2003 to 2014, between ages 18–85 years, follow-up through...

10.3389/fcvm.2023.1140160 article EN cc-by Frontiers in Cardiovascular Medicine 2023-04-19

Bacillus amyloliquefaciens is a nonpathogenic microorganism whose highly active amylase widely isolated from soil and plants. TL106 an isolate of cold- disease-resistant Tibetan pigs in Linzhi, Tibet. Here, we report that not only could survive acidic environments, high bile salt concentrations, high-temperature conditions but also was resistant to antibiotics. It significantly improved the growth performance weaned piglets, especially prevention diarrhea. The crude fiber ash digestibility...

10.1128/spectrum.01205-21 article EN cc-by Microbiology Spectrum 2022-01-26

10.1016/j.matt.2023.01.033 article EN publisher-specific-oa Matter 2023-03-01

Tibial dyschondroplasia (TD) is a metabolic disease of young poultry that affects bone andcartilage's growth. It mostly occurs in broilers due to thiram toxicity the feed. In this disease, tibial cartilage not yet ripe for ossification, but it also results lameness, death, and moral convictions commercial numerous apoptotic changes on cell level. These serve cardinal role situation. Many potential problems indicate chlorogenic acid (CGA) performs an extensive controlling apoptosis's...

10.1016/j.ecoenv.2021.112059 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-02-27

Thiram is a dithiocarbamate pesticide extensively used as fungicide to preserve crops and seeds. Long-term exposure thiram causes potential harm the health of human beings animals. So far, most researches on focused erythrocyte toxicity, immune system, kidney damage, tibial dyschondroplasia; however, there less data cardiac toxicity. In this study, we examined histopathology, inflammatory factors, oxidative stress indicators, apoptosis markers in heart broilers that were exposed thiram....

10.1016/j.ecoenv.2022.114225 article EN cc-by Ecotoxicology and Environmental Safety 2022-10-23

Thiram causes tibial dyschondroplasia in broilers, leading to a significant economic loss the poultry industry. Our study explored effects of taurine thiram induced (TD) through vivo and vitro approches. In study, resulted lameness disorder, low production parameters ALP, ACP, high level NOS. While, exhibited promising effect by reducing lameness, increasing ACP levels, significantly lowering NOS with restoration growth plate. caused distortion disintegration chondrocytes. The CCK-8...

10.1016/j.ecoenv.2021.112981 article EN cc-by Ecotoxicology and Environmental Safety 2021-11-12

Abstract Background Dyslipidemia frequently coexists with hypertension in the population. Apolipoprotein B (ApoB) is increasingly considered a more potent predictor of cardiovascular disease (CVD). Abnormal levels serum ApoB can potentially impact mortality risk. Methods The prospective cohort study employed data from National Health and Nutrition Examination Survey (NHANES), which was performed between 2005 2016, follow-ups extended until December 2019. Serum concentrations were quantified...

10.1186/s12872-024-03949-1 article EN cc-by BMC Cardiovascular Disorders 2024-05-24

Mycoplasma bovis (M. bovis) is one of the most important pneumonia pathogens in yaks. It may result more economic losses due to cold and anoxia condition at Qinghai Tibetan plateau. However, date, limited information on M. infection yaks available China. For this purpose, seroprevalence was investigated living mentioned area through commercial ELISA kits. A total 959 were incorporated into study. The prevalence disease 48.70%. serological results revealed a relatively high present study...

10.1155/2021/6646664 article EN cc-by BioMed Research International 2021-04-14
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