A5090440378- Antibiotic Resistance in Bacteria
- Microbial infections and disease research
- Antimicrobial Resistance in Staphylococcus
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial Identification and Susceptibility Testing
- Salmonella and Campylobacter epidemiology
- Nail Diseases and Treatments
- Clostridium difficile and Clostridium perfringens research
- Enterobacteriaceae and Cronobacter Research
- Genomics and Phylogenetic Studies
- Bacterial biofilms and quorum sensing
- Animal Disease Management and Epidemiology
- Milk Quality and Mastitis in Dairy Cows
- Animal Virus Infections Studies
- Animal Behavior and Welfare Studies
- Gene expression and cancer classification
- Metabolomics and Mass Spectrometry Studies
- Dietetics, Nutrition, and Education
- Agriculture Sustainability and Environmental Impact
- Identification and Quantification in Food
- Complementary and Alternative Medicine Studies
- Escherichia coli research studies
- Bacterial Genetics and Biotechnology
- Antibiotic Use and Resistance
- Medical Imaging and Pathology Studies
Finnish Food Authority
2013-2023
Research Institute of the Finnish Economy
2008
WGS-based antimicrobial susceptibility testing (AST) is as reliable phenotypic AST for several antimicrobial/bacterial species combinations. However, routine use of hindered by the need bioinformatics skills and knowledge resistance (AMR) determinants to operate vast majority tools developed date. By leveraging on ResFinder PointFinder, two freely accessible that can also assist users without skills, we aimed at increasing their speed providing an easily interpretable antibiogram output.The...
Abstract The discovery of antibiotics more than 80 years ago has led to considerable improvements in human and animal health. Although antibiotic resistance environmental bacteria is ancient, pathogens thought be a modern phenomenon that driven by the clinical use 1 . Here we show particular lineages methicillin-resistant Staphylococcus aureus —a notorious pathogen—appeared European hedgehogs pre-antibiotic era. Subsequently, these spread within local hedgehog populations between secondary...
Introduction Carbapenemase-producing Enterobacteriaceae (CPE) have rarely been reported in dogs, and never animals Finland. However, April 2015, two meropenem-resistant Escherichia coli were identified from dogs one family. Both suffered chronic otitis externa . Methods: Epidemiological molecular investigations (pulsed-field gel electrophoresis (PFGE), multilocus sequence typing) conducted to investigate the source of infection transmission routes. Results: In both family member New Delhi...
Methicillin-resistant Staphylococcus aureus (MRSA) Sequence Type (ST)1, Clonal Complex(CC)1, SCCmec V is one of the major Livestock-Associated (LA-) lineages in pig farming industry Italy and associated with pigs other European countries. Recently, it has been increasingly detected Italian dairy cattle herds. The aim this study was to analyse differences between ST1 MRSA methicillin-susceptible S. (MSSA) from herds Europe human isolates. Sixty-tree animal isolates different holdings 20 were...
Antimicrobial resistance (AMR) should be tackled through a One Health approach, as stated in the World Organization Global Action Plan on AMR. We describe landscape of AMR surveillance European Union/European Economic Area (EU/EEA) and underline gap regarding veterinary medicine. Current efforts are limited help to practitioners policymakers seeking improve antimicrobial stewardship animal health. propose establish Resistance Surveillance network Veterinary medicine (EARS-Vet) report...
Plasmid-mediated extended-spectrum beta-lactamase (ESBL), AmpC, and carbapenemase producing Enterobacteriaceae, in particular Escherichia coli Klebsiella pneumoniae , with potential zoonotic transmission routes, are one of the greatest threats to global health. The aim this study was investigate food products as vehicles for ESBL/AmpC-producing bacteria identify plasmids harboring resistance genes. We sampled 200 purchased from Finland capital region during fall 2018. Products originated 35...
Introduction The purpose of this study was to describe a nosocomial outbreak caused by methicillin resistant Staphylococcus pseudintermedius (MRSP) ST71 SCCmec II-III in dogs and cats at the Veterinary Teaching Hospital University Helsinki November 2010 – January 2012, determine risk factors for acquiring MRSP. In addition, measures control current policy MRSP prevention are presented. Methods Data patients were collected from hospital patient record software. surveillance data acquired...
Methicillin-resistant staphylococci (MRS) are increasingly being isolated in bovine mastitis. The aim of our study was to evaluate the occurrence MRS Finnish mastitis milk samples and characterize isolates using molecular methods.Methicillin-resistant S. aureus (MRSA) a rare finding Finland. Only two out 135 (1.5%) were positive for mec genes. One these carried mecA spa type t172, SCCmec IV ST375, other harboured mecC, t3256, ST130. MRSA ST375 is common among human Finland, but this first...
Summary Backyard poultry has become increasingly popular in industrialized countries. In addition to keeping chickens for eggs and meat, owners often treat the birds as pets. However, several pathogenic enteric bacteria have potential zoonotic transmission from humans but very little is known about occurrence of pathogens backyard flocks. The antimicrobial resistance Salmonella enterica , Campylobacter spp., Listeria monocytogenes enteropathogenic Yersinia spp. was studied 51 voluntary...
Coagulase-negative staphylococci (CoNS) are the most common bovine mastitis causing bacteria in many countries. It is known that resistance for antimicrobials general more CoNS than Staphylococcus aureus but little about antimicrobial of specific species. In this study, 400 isolates from mastitic milk samples were identified to species level using ribotyping and MALDI-TOF MS, their susceptibility was determined a commercially available microdilution system. The results interpreted according...
Introduction As part of the EU Joint Action on Antimicrobial Resistance (AMR) and Healthcare-Associated Infections, an initiative has been launched to build European AMR Surveillance network in veterinary medicine (EARS-Vet). So far, activities included mapping national systems for surveillance animal bacterial pathogens, defining EARS-Vet objectives, scope, standards. Drawing these milestones, this study aimed pilot test surveillance, namely (i) assess available data, (ii) perform...
The objective of our study was to clinically and etiologically investigate acute outbreaks respiratory disease in Finland. Our also aimed evaluate the clinical use various methods diagnosing infections under field conditions describe antimicrobial resistance profile main bacterial pathogen(s) found during study. A total 20 case herds having finishing pigs showing symptoms eight control no signs suggesting problems were enrolled Researchers visited each herd twice, examining bleeding per...
Summary Antimicrobial susceptibility was determined for 805 domestic Campylobacter jejuni isolates obtained from broilers ( n = 459), bovines 120), human patients 95), natural waters 80), wild birds 35) and zoo animals/enclosures 16) with known multilocus sequence types MLST ) 450 isolates. The minimum inhibitory concentration MIC values erythromycin, tetracycline, streptomycin, gentamicin the quinolones ciprofloxacin nalidixic acid were Vet method. s compared to find possible associations...
In pigs, antimicrobial use (AMU) practices vary at different production phases between herds and countries. Antimicrobial resistance (AMR) development is linked to AMU but recognized as a multi-factorial issue, thus, any information increasing knowledge of AMR relationships valuable. We described screened the carriage phenotypes indicator Escherichia coli in 25 selected Finnish piglet-producing finishing that formed nine birth-to-slaughter lines. Moreover, we studied associations both herd...
A total of 502 Campylobacter jejuni isolates from poultry in 12 different European countries (10 them the largest production Europe) were whole genome sequenced to examine genomic diversity fluoroquinolone resistant (FQ‐R) and susceptible (FQ‐S) C. across producing determine whether emergence resistance among is related transmission through or selection use individual countries. high was observed. The clustered four main clusters. All trees revealed that according presence/absence gyrA...
Abstract Background Extended-spectrum β-lactamase producing Enterobacterales (ESBL-E) are important causative agents for infections in humans and animals. At the Equine Veterinary Teaching Hospital of University Helsinki, first caused by ESBL-E were observed at end 2011 leading to enhanced infection surveillance. Contact patients screened culturing sites rectal screening. This study was focused on describing epidemiology microbiological characteristics from equine EVTH during 2011–2014,...
Over the past two decades, livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) has become widely prevalent in pig production Europe. The carriage status of LA-MRSA is known to vary among individual pigs, but bacterial load pigs rarely been studied. We assessed quantity nasal and skin samples investigated genetic diversity strains together with sequenced from national surveillance pathology Finnish Food Authority. On farms assumed MRSA-positive status, farm 1 2, 10...
Monien maa- ja elintarviketalouden kannalta merkittävien bakteeritaudinaiheuttajien luotettava tunnistus on ongelmallista. Näihin lukeutuvat perunan uusi, siemenlevintäinen taudinaiheuttaja pohjanrupibakteeri (Streptomyces turgidiscabies), voimakasta hermomyrkkyä tuottava, vakavia ruokamyrkytyksiä halvauksia aiheuttava, elintarvikkeissa kulkeutuva Clostridium botulinum, sekä ihmisille tautia aiheuttavat enterohemorragiset Escherichia coli -bakteerit (EHEC-bakteerit;...