A5030300491- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Medical Image Segmentation Techniques
- Optical Coherence Tomography Applications
- Cardiovascular Function and Risk Factors
- Advanced Vision and Imaging
- Autoimmune and Inflammatory Disorders Research
- Retinal and Macular Surgery
- Systemic Lupus Erythematosus Research
- Angiogenesis and VEGF in Cancer
- Impact of Light on Environment and Health
- Cardiomyopathy and Myosin Studies
- Advanced Neuroimaging Techniques and Applications
- Image and Object Detection Techniques
- Virtual Reality Applications and Impacts
- Advanced MRI Techniques and Applications
- Advanced Image and Video Retrieval Techniques
- Video Surveillance and Tracking Methods
- Systemic Sclerosis and Related Diseases
- Renal and Vascular Pathologies
- Digital Imaging for Blood Diseases
- Augmented Reality Applications
St. Franziskus Hospital
2017-2025
University of Münster
2005-2011
Abstract Neovascular age-related macular degeneration (nAMD) is one of the major causes irreversible blindness and characterized by accumulations different lesions inside retina. AMD biomarkers enable experts to grade could be used for therapy prognosis individualized treatment decisions. In particular, intra-retinal fluid (IRF), sub-retinal (SRF), pigment epithelium detachment (PED) are prominent grading neovascular AMD. Spectral-domain optical coherence tomography (SD-OCT) revolutionized...
Abstract Concepts for ventricular function tend to assume that the majority of myocardial cells are aligned with their long axes parallel epicardial surface. We aimed validate existence aggregates orientated axis intruding obliquely between and endocardial surfaces quantitate amount angulation. To compensate changing angle myocytes relative equatorial plane ventricles varying depths within walls, so‐called helical angle, we used pairs cylindrical knives different diameters punch semicircular...
Background: Anti-Vascular Endothelial Growth Factor (VEGF) therapy is an effective for improving and stabilizing the vision of patients with neovascular age-related macular degeneration (nAMD). However, treatment requirements, particularly number intraocular injections, can vary significantly among patients. This study aimed to analyze vascular characteristics neovascularizations (MNVs) identify potential biomarkers that could predict required injection frequency throughout disease course....
Abstract Purpose To investigate the progression characteristics of ellipsoid zone ( EZ ) loss in eyes with macular telangiectasia type 2 (MacTel) as reflected by area and linear measurements, their relevance for visual acuity. Methods Participants were selected from MacTel Study cohort. Linear measurements performed Spectral‐Domain Optical Coherence Tomograph (SD‐OCT) volume scans. Progression correlations between analysed using mixed effects models. Results A total 134 70 patients included...
To evaluate whether optical coherence tomography angiography (OCTA) can detect altered vessel density (VD) at the optic nerve head (ONH) in glaucoma patients. Special attention is paid to accuracy of OCTA technique for distinguishing healthy from glaucomatous eyes.A total 171 eyes were examined by system AngioVue™ (Optovue): 97 diagnosed with and 74 control eyes. The papillary peripapillary VD was measured. Furthermore, correlated different structural functional measurements. In order test...
Abstract The purpose of this study was to ascertain whether a correlation exists between glaucoma-associated alteration ocular vascular haemodynamics and endothelin-1 (ET-1) levels exist. Eyes patients with cataract (n = 30) or glaucoma 68) were examined optical coherence tomography (OCT) OCT-angiography (OCT-A; AngioVue™-RTVue-XR; Optovue, Fremont, California, USA). peripapillary the macular vessel density (VD) values measured. Inferior superior retinal nerve fibre layer (RNFL) thickness...
Background: The clinical appearance of macular neovascularization (MNV) in age-related degeneration (nAMD) varies widely, but so far, this has had no relevance terms therapeutic approaches or prognosis. Therefore, our purpose was to investigate if and which differences exist the vascular architecture MNV quantify them. Methods: In 90 patients with newly diagnosed nAMD, identified by means optical coherence tomography angiography (OCTA), automated quantitative analysis carried out. analyzed...
A fully-articulated visual representation of a user in an immersive virtual environment (IVE) can enhance the user's subjective sense feeling present world. Usually this requires to wear full-body motion capture suit track real-world body movements and map them model. In paper we augmented virtuality approach that allows incorporate realistic view oneself environments using cameras attached head mounted displays. The described system easily be integrated into typical reality setups....
A mobile computer vision system is presented that helps visually impaired pedestrians cross roads. The detects pedestrian lights in the environment and gives feedback about current phase of crucial light. For this purpose live video stream a phone analyzed four steps: localization, classification, analysis, time-based verification. In particular, temporal analysis allows us to alleviate inherent problems such as occlusions (by vehicles), falsified colors, others, further increase decision...
Objective. Enthesitis-related arthritis (ERA) represents a subgroup of juvenile idiopathic (JIA) that is regularly accompanied by anterior uveitis. This study describes the prevalence and characteristics ERA-related Methods. Cross-sectional data from National Pediatric Rheumatological Database (NPRD) were used to characterize uveitis (ERA-U). In addition sociodemographic variables, we documented occurrence course disease, including symptoms, visual acuity, complications, as well JIA such...
Optical coherence tomography angiography (OCT-A) enables detailed visualisation of the vascular structure choroidal neovascularisation (CNV). The aim this study was to determine whether mathematically ascertained OCT-A parameters type 1 and 2 CNV in exudative age-related macular degeneration (AMD) change during antivascular endothelial growth factor (anti-VEGF) treatment. were also compared with previously obtained activity (fluid distribution on spectral domain OCT (SD-OCT)) establish they...
Abstract Purpose To characterize the choriocapillaris (CC) structure in relation to subretinal fluid (SRF) as a possible systematic error source using spectral domain (SD-OCTA) compared swept-source optical coherence tomography angiography (SS-OCTA). Methods This is prospective case-control study of 23 eyes. Ten patients with acute central serous chorioretinopathy (CSC), three partial macular-off retinal detachment (RD) and ten healthy, age-matched controls were included. Abnormal CC...
Pairs of cylindrical knives were used to punch semicircular slices from the left basal, sub-basal, equatorial, and apical ventricular wall porcine hearts. The sections extended epicardium endocardium. Their shape compensated for depth-related changing orientation myocytes relative equatorial plane. analyzed by diffusion tensor magnetic resonance imaging. primary eigenvector was determined in each pixel calculate number angle intrusion long axis aggregated epicardial surface. Arrays axially...
In this paper we propose an algorithm for combining multiple image segmentations to achieve a final improved segmentation. contrast previous works consider the most general class of segmentation combination, i.e. each input has arbitrary number regions. Our approach is based on random walker which able provide high-quality starting from manually specified seeds. We automatically generate such seeds ensemble. An information-theoretic optimality criterion proposed determine The experimental...
To analyze the binding patterns of serum autoantibodies from juvenile idiopathic arthritis (JIA) and JIA-associated uveitis (JIAU) patients to proteomes different ocular tissues identify potential autoantigens in JIAU. Proteomes porcine iris, ciliary body, or retina tissue were isolated, separated using 2D-gel electrophoresis, transferred a blotting membrane. The pattern antibodies JIA JIAU healthy controls proteins was visualized by anti-human IgG secondary chemiluminescence reaction....
Background Macular telangiectasia type 2 (MacTel) is a neurodegenerative disease resulting in photoreceptor loss. Optical coherence tomography (OCT) reveals outer retina-associated hyperreflectivity (ORaH) as part of this process. The purpose study was to describe the incidence and phenotypical variation ORaH. Methods Different parameters ORaH were analysed: OCT characteristics (Spectralis SD-OCT), correlation with vascular changes (OCT angiography; OCTA 3×3 mm Optovue) hyperpigmentation...