Frederic Gunnemann

ORCID: 0000-0003-0942-892X
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Glaucoma and retinal disorders
  • Retinal Imaging and Analysis
  • Retinal and Macular Surgery
  • Retinal and Optic Conditions
  • Peripheral Artery Disease Management
  • Coronary Interventions and Diagnostics
  • Cerebrovascular and Carotid Artery Diseases
  • Retinal Development and Disorders
  • Angiogenesis and VEGF in Cancer
  • Corneal surgery and disorders
  • Cerebral Venous Sinus Thrombosis
  • Advanced Biosensing Techniques and Applications
  • Renal and Vascular Pathologies
  • Optical Coherence Tomography Applications
  • Intraocular Surgery and Lenses

St. Franziskus Hospital
2016-2021

University of California, Los Angeles
2020-2021

Doheny Eye Institute
2021

Purpose To evaluate the various patterns of subretinal fluid (SRF) in eyes with age-related macular degeneration (AMD) absence neovascularisation (MNV) and to assess long-term outcomes these eyes. Methods This retrospective study included only non-neovascular AMD associated SRF. Eyes evidence MNV were excluded. Spectral-domain optical coherence tomography (SD-OCT) was obtained at baseline follow-up, qualitative quantitative SD-OCT analysis drusen including drusenoid pigment epithelial...

10.1136/bjophthalmol-2020-317326 article EN British Journal of Ophthalmology 2020-09-12

Pneumatic retinopexy (PnR) is associated with superior visual acuity and reduced vertical metamorphopsia compared pars plana vitrectomy (PPV) for primary rhegmatogenous retinal detachment (RRD). It important to determine postoperative photoreceptor integrity both surgical techniques.To compare on spectral domain-optical coherence tomography (SD-OCT) between PnR PPV at 12 months postoperatively.Post hoc analysis of the Retinopexy Versus Vitrectomy Management Primary Rhegmatogenous Retinal...

10.1001/jamaophthalmol.2021.0803 article EN JAMA Ophthalmology 2021-04-22

Abstract Purpose To investigate the progression characteristics of ellipsoid zone ( EZ ) loss in eyes with macular telangiectasia type 2 (MacTel) as reflected by area and linear measurements, their relevance for visual acuity. Methods Participants were selected from MacTel Study cohort. Linear measurements performed Spectral‐Domain Optical Coherence Tomograph (SD‐OCT) volume scans. Progression correlations between analysed using mixed effects models. Results A total 134 70 patients included...

10.1111/aos.14110 article EN Acta Ophthalmologica 2019-04-09

Purpose: To analyze the evolution of type 1 neovascularization associated with vascularized serous pigment epithelial detachment (vsPED) using three-dimensional, volumetric, en face optical coherence tomography angiography (OCTA). Methods: This was a retrospective case series from four tertiary medical centers. OCTA images were analyzed at baseline and 3-, 6-, 12-, 18-, 24-month follow-up visit when available. Visual acuity, number injections, PED maximal height area volume, choroidal (CNV)...

10.1167/iovs.18-26478 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2019-08-01

Background Macular telangiectasia type 2 (MacTel) is a neurodegenerative disease resulting in photoreceptor loss. Optical coherence tomography (OCT) reveals outer retina-associated hyperreflectivity (ORaH) as part of this process. The purpose study was to describe the incidence and phenotypical variation ORaH. Methods Different parameters ORaH were analysed: OCT characteristics (Spectralis SD-OCT), correlation with vascular changes (OCT angiography; OCTA 3×3 mm Optovue) hyperpigmentation...

10.1136/bjophthalmol-2020-317997 article EN British Journal of Ophthalmology 2021-01-07

Purpose: To evaluate the depth and pattern of retinal hemorrhage in acute central vein occlusion (CRVO) to correlate these with visual anatomic outcomes. Methods: Retinal hemorrhages were evaluated color fundus photography fluorescein angiography at baseline follow-up. Snellen acuity (VA), foveal thickness (CFT), extent ischemia, development neovascularization analyzed. Results: 108 eyes from patients evaluated. Mean age was 63.6 ± 16.1 years a predilection for right eye (73.1%). Average...

10.1167/iovs.61.5.54 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2020-05-27

Zusammenfassung Hintergrund Ziel der vorliegenden Studie war es, Veränderungen von Typ-2-CNV (klassische CNV) in OCT-Angiografie (OCT-A) unter Anti-VEGF-Therapie aufzuzeigen und die Abgrenzbarkeit Läsion vom umgebenden Gewebe unterschiedlichen Segmentierungen zu untersuchen. Methode Bei 12 Patienten wurde Fluoreszenzangiografie (FAG) im SD-OCT eine gut abgrenzbare mit assoziierten exsudativen diagnostiziert. allen zudem OCT-A (Avanti, Optovue) vorgenommen. Diese Befunde wurden initial, nach...

10.1055/s-0043-118346 article DE Klinische Monatsblätter für Augenheilkunde 2017-09-01

Anti-VEGF therapy is the standard treatment for exudative neovascular age-related macular degeneration (nAMD) caused by development of neovascularisation (MNV) with associated fluid exudation. The therapeutic strategies (T&E or PRN) assumed a scarring transformation MNV and exit were formulated accordingly. present study investigates this hypothesis as real-life long-term analysis.

10.1055/a-2239-6394 article EN Klinische Monatsblätter für Augenheilkunde 2024-01-05

Background Retinal pigment epithelium (RPE) tears are a typical complication of vascular detachment in age-related macular degeneration (AMD). During proactive intense anti-VEGF therapy, stabilisation or improvement function may occur. With the new method OCT angiography (OCT-A), retinal vessels and flow density can be quantified. This pilot study investigates changes choriocapillars (CC) areas with increasing FAF following an RPE-tear. Methods In six eyes RPE-tear, prospectively initially...

10.1055/s-0043-118344 article DE Klinische Monatsblätter für Augenheilkunde 2017-09-01

Zusammenfassung Hintergrund Ziel der vorliegenden erweiterten Fallbeschreibung ist die Darstellung choroidaler Neovaskularisationen (CNV) bei vaskularisierten Pigmentepithelabhebungen (PE-Abhebung) initial und unter Anti-VEGF-Therapie mittels OCT-Angiografie (OCT-A) im Vergleich zur konventionellen Diagnostik. CNV-Größe Flow-Areal wurden in OCT-A quantifiziert diese Befunde mit anderen SD-OCT-Charakteristika Läsion verglichen. Patienten Methode Bei 8 vaskularisierter PE-Abhebung wurde...

10.1055/s-0043-118345 article DE Klinische Monatsblätter für Augenheilkunde 2017-09-01
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