Silvia Pittalis
A5068238409- Viral Infections and Outbreaks Research
- COVID-19 Clinical Research Studies
- HIV Research and Treatment
- Disaster Response and Management
- HIV/AIDS drug development and treatment
- Viral Infections and Vectors
- Surgical site infection prevention
- COVID-19 epidemiological studies
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Cardiac, Anesthesia and Surgical Outcomes
- SARS-CoV-2 detection and testing
- Tuberculosis Research and Epidemiology
- Poxvirus research and outbreaks
- Zoonotic diseases and public health
- Urinary Tract Infections Management
- HIV/AIDS Research and Interventions
- Mosquito-borne diseases and control
- Respiratory viral infections research
- Bacillus and Francisella bacterial research
- Hepatitis C virus research
- Respiratory Support and Mechanisms
- Herpesvirus Infections and Treatments
- Tissue Engineering and Regenerative Medicine
- HIV/AIDS oral health manifestations
University of Rome Tor Vergata
2024
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani
2013-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2006-2022
Fundación Juan March
2012
Regione Puglia
2011
University of Padua
2003
Since May 2022, an outbreak of monkeypox has been ongoing in non-endemic countries. We report four cases Italy young adult men reporting condomless sexual intercourse. The patients are good clinical condition with no need for specific antiviral drugs. Biological samples from seminal fluid were positive viral DNA. For many other viruses found semen there is evidence transmission. possibility transmission virus needs to be investigated.
IntroductionSeveral recent case reports have described common early chest imaging findings of lung pathology caused by 2019 novel Coronavirus (SARS-COV2) which appear to be similar those seen previously in SARS-CoV and MERS-CoV infected patients.ObjectiveWe present some remarkable the first two patients identified Italy with COVID-19 infection travelling from Wuhan, China. The follow-up X-Rays CT scans was also included, showing a progressive adult respiratory distress syndrome...
Abstract Background Remdesivir is a prodrug of the nucleoside analogue GS-441524 and under evaluation for treatment SARS-CoV-2-infected patients. Objectives To evaluate pharmacokinetics remdesivir in plasma, bronchoalveolar aspirate (BAS) CSF two critically ill COVID-19 Methods was administered at 200 mg loading dose on first day followed by 12 days 100 Blood samples were collected immediately after (C0) 1 (C1) 24 h (C24) intravenous administration 3 until 9. BAS Days 4, 7 9 from both...
We report two cases of Corona Virus Disease-19 (COVID-19) in patients with Down Syndrome (DS) and describe the identification, diagnosis, clinical course management infection. Syndrome, which is caused by trisomy 21, characterized immune dysregulation, anatomical differences upper respiratory tract higher rate comorbidities. All these risk factors can contribute to more severe presentations COVID-19 this population. It essential raise awareness relevance SARS-COV-2 infection DS patients, as...
Abstract Background The number of leishmaniasis cases associated with immunosuppression has increased regularly over the past 20 years. Immunosuppression related to HIV infection, immunosuppressive treatment, organ transplantation, and neoplastic diseases increases risk for Leishmania -infected people develop visceral illness. Case presentation Three infantum in corticosteroid (CS)-treated patients are reported: an isolated lingual a farmer treated CS asthma, severe cutaneous lesions woman...
Transmitted drug resistance (TDR) is still a critical aspect for the management of individuals living with HIV-1. Thus, its evaluation crucial to optimize HIV care.
There is still wide variability in surgical antimicrobial prophylaxis (SAP) practice by different teams and specialties, with potential impact on adverse events the emergence of antibiotic resistance.We assessed SAP appropriateness a regional prospective multicenter study basis agreement Surgical Care Improvement Project indicators (SCIP-Inf) Italian guidelines (GL).Prophylaxis was administered 2,664 2,835 procedures (94%): In 2,346 2,468 (95%) as indicated 318 367 (86.6%) which they were...
Transmitted drug-resistance (TDR) remains a critical aspect for the management of HIV-1-infected individuals. Thus, studying dynamics TDR is crucial to optimize HIV care. In total, 4323 HIV-1 protease/reverse-transcriptase sequences from drug-naive individuals diagnosed in north and central Italy between 2000 2014 were analysed. was evaluated over time. Maximum-likelihood Bayesian phylogenetic trees with bootstrap Bayesian-probability supports defined transmission clusters. Most males...
Action on social determinants is a main component of the World Health Organization End Tuberculosis (TB) Strategy. The aim study was to collect information socioeconomic characteristics and biomedical risk factors in migrant TB patients Italy compare it with data collected among Italian patients. A cross-sectional conducted aged ≥18 years over 12-months enrolment period 12 major hospitals. Information education, employment, housing income collected, European Union Statistics Income Living...
Torquetenovirus (TTV) is the most abundant component of human blood virome and its replication controlled by a functioning immune system. In this study, TTV was evaluated in 21 people with acute HIV infection (AHI) reconstitution following antiretroviral therapy (ART). PBMC-associated HIV-1 DNA, as well plasma RNA, were measured real-time PCR. CD4 CD8 differentiation, activation, exhaustion, senescence phenotypes analyzed flow cytometry. Thirteen healthy donors (HD) twenty-eight chronically...
Molecular investigation of primary HIV infections (PHI) is crucial to describe current dynamics transmission. Aim the study was investigate transmission clusters (TC) in PHI referred during years 2013–2020 National Institute for Infectious Diseases Rome (INMI), that Lazio regional AIDS reference centre, and factors possibly associated with inclusion TC. These were identified by phylogenetic analysis, based on population sequencing pol; a more depth analysis performed TC B subtype, using...
HIV testing was offered to 2,185 people receiving mpox (formerly monkeypox) vaccination, who reported not being positive. Among them 390 were current PrEP users, and 131 had taken in the past. Of 958 individuals consenting testing, six newly diagnosed with HIV. Two patients symptomatic primary infection. None of ever PrEP. Mpox vaccination represents an important opportunity for counselling about risk reduction
Sampling Surfaces for Ebola Virus Persistence After Cleaning Procedures in High-Level Isolation Settings: The Experience With 2 Patients at the Lazzaro Spallanzani National Institute Infectious Diseases - Volume 37 Issue 6