Hong Yu

ORCID: 0000-0002-4425-3697
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About
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Research Areas
  • Lung Cancer Research Studies
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • Brain Metastases and Treatment
  • Gastric Cancer Management and Outcomes
  • Bladder and Urothelial Cancer Treatments
  • Radiomics and Machine Learning in Medical Imaging
  • Viral-associated cancers and disorders
  • Estrogen and related hormone effects
  • Cancer Immunotherapy and Biomarkers
  • MicroRNA in disease regulation
  • Epigenetics and DNA Methylation
  • Immune Cell Function and Interaction
  • MRI in cancer diagnosis
  • Medical Imaging Techniques and Applications
  • Bone Tumor Diagnosis and Treatments
  • Sarcoma Diagnosis and Treatment
  • Peptidase Inhibition and Analysis
  • Melanoma and MAPK Pathways
  • Colorectal and Anal Carcinomas
  • Immune cells in cancer
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • RNA modifications and cancer
  • Receptor Mechanisms and Signaling
  • Hypothalamic control of reproductive hormones

Shanghai Jiao Tong University
2023-2024

Shanghai Chest Hospital
2023-2024

Taizhou People's Hospital
2024

Nanjing Medical University
2024

Nantong University
2024

Qingdao University
2017-2023

Affiliated Hospital of Qingdao University
2017-2023

<i>Aims:</i> The <i>GPR54</i> gene has been proved to be important in the process of puberty onset, yet no association study performed evaluate effect polymorphisms on central precocious (CPP). This was designed scan for and investigate relationships between genotypes disease. <i>Methods:</i> 272 Chinese Han girls diagnosed CPP patients were recruited as case group 288 unrelated normal control group. whole directly sequenced randomly selected samples,...

10.1159/000107511 article EN Neuroendocrinology 2007-01-01

Pancreatic adenocarcinoma (PAAD) remains challenging to diagnose and treat clinically due its difficult early diagnosis, low surgical resection rate, high risk of postoperative recurrence metastasis. SMAD4 is a classical mutated gene in pancreatic cancer lost up 60%-90 % PAAD patients, mutation often predicts poor prognosis treatment resistance. In this study, based on the expression profile data The Cancer Genome Atlas database, we identified ceRNA network composed 2 lncRNAs, 1 miRNA, 4...

10.1016/j.heliyon.2024.e24287 article EN cc-by-nc-nd Heliyon 2024-01-01

Chest computed tomography (CT) is a critical tool in the diagnosis of pulmonary cryptococcosis as approximately 30% normal immunity individuals may not exhibit any significant symptoms or laboratory findings. Pulmonary granuloma and lung adenocarcinoma can appear similar on noncontrast chest CT. This study evaluates use an integrated model that was developed based radiomic features combined with demographic radiological to differentiate nodules from adenocarcinomas.Preoperative CT images for...

10.21037/tlcr-23-389 article EN Translational Lung Cancer Research 2023-08-01

Background:: Some patients with suspected brain metastases (BM) could not tolerate longer scanning examinations according to the standardized MRI protocol. Objective:: The purpose of this study was evaluate clinical value contrast-enhanced fast fluid-attenuated inversion recovery (CE FLAIR) imaging in combination T1 weighted T1WI) detecting BM lung cancer and explore a quick effective Material Methods:: In 201 cancers BM, T1WI FLAIR were performed before after administration gadopentetate...

10.2174/0115734056288838240201040400 article EN cc-by Current Medical Imaging Formerly Current Medical Imaging Reviews 2024-02-28

The pathological sub-classification of lung cancer is crucial in diagnosis, treatment and prognosis for patients. Quick timely identification subtypes from imaging examinations rather than histological tests could help guiding therapeutic strategies. aim the study to construct a non-invasive radiomics-based model predicting on brain metastases (BMs) multiple magnetic resonance (MRI) sequences. One hundred sixty-one patients primary with synchronous BMs [121 adenocarcinoma (AD); 40 small cell...

10.21037/tcr-24-1147 article EN Translational Cancer Research 2024-12-01

Primary pulmonary lymphoepithelial carcinoma (PLEC) is a rare subtype of nonsmall cell lung cancer. This study aimed to investigate the clinicopathological and prognostic characteristics resected primary PLEC.In this retrospective study, 95 consecutive patients with PLEC, who received radical surgical resection treatment, were examined from October 2009 January 2022. The features their association survival outcomes analyzed.Primary PLEC predominated in relatively younger nonsmokers, lacked...

10.1002/jso.27309 article EN Journal of Surgical Oncology 2023-05-11

<div>Abstract<p>The tumor microenvironment impacts progression and individual cells, including CD4<sup>+</sup> T which have been detected in bladder cancer tissues. The detailed mechanism of how these cells were recruited to the their impact on progression, however, remains unclear. Using a human clinical sample survey <i>in vitro</i> coculture system, we found that has greater capacity recruit than surrounding normal consequences higher levels included...

10.1158/1535-7163.c.6539107 preprint EN 2023-04-03
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