A5101502305- Occupational and environmental lung diseases
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lung Cancer Treatments and Mutations
- Cerebrovascular and Carotid Artery Diseases
- Microfluidic and Capillary Electrophoresis Applications
- Medical Research and Treatments
- Neurological Disease Mechanisms and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Radiation Dose and Imaging
- Cancer Immunotherapy and Biomarkers
- Cardiovascular Health and Disease Prevention
- Dialysis and Renal Disease Management
- Infrared Thermography in Medicine
- Cholinesterase and Neurodegenerative Diseases
- Immune Response and Inflammation
- Mechanisms of cancer metastasis
- Biomarkers in Disease Mechanisms
- Chromatin Remodeling and Cancer
- Peptidase Inhibition and Analysis
- Geometric Analysis and Curvature Flows
- Advanced Drug Delivery Systems
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024
Seattle University
2023
University of Utah
2023
Shanghai Jiao Tong University
2015-2023
McMaster University
2023
College of Charleston
2023
Massachusetts Institute of Technology
2023
University of Oxford
2023
Universidad Carlos III de Madrid
2023
University of North Carolina at Chapel Hill
2023
Western blotting is a commonly used protein assay that combines the selectivity of electrophoretic separation and immunoassay. The technique limited by long time, manual operation with mediocre reproducibility, large sample consumption, typically 10-20 μg per assay. blots are also usually to measure only one an additional housekeeping for normalization. Measurement multiple proteins possible; however, it requires stripping membranes antibody then reprobing second antibody. Miniaturized...
Abstract Immune checkpoint inhibitor (ICI) rechallenge in non‐small cell lung cancer (NSCLC) is a promising therapeutic strategy. The situation for ICI can be divided into three categories: adverse events (AEs); resistance to ICIs, and becomes compulsive because of tumor relapse while the patients had completed 2 year course immunotherapy. However, these categories are still controversial should explored further. Through voting at 6th Straits Summit Forum on Lung Cancer, this study we...
Soy phytoestrogen is often used as hormone replacement therapy to alleviate the symptoms of menopause in postmenopausal women. Since estrogen has been considered an important risk factor for development breast carcinoma, we need know whether it safe these women with cancer take soy foods that are rich phytoestrogen. In present study, investigated efficacy on tumor proliferation, apoptosis, and angiogenesis mammary tumors had already formed ovariectomized rats. We found phytochemical...
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> A voltage-controlled integrated antenna oscillator (VCIAO) integrating a differential (VCO) with double-sided parallel-strip line (DSPSL)-fed quasi-Yagi based on the DSPSL is presented in this paper. The used not only as radiating element, but also output power combiner and resonating load of VCO without any matching circuits or transition between them. two sub-oscillators opposite sides...
To explore the relationship between circulating sclerostin levels and pulse wave velocity (PWV) in prevalent hemodialysis (HD) patients.154 HD patients were enrolled examined for serum level, carotid-femoral (cf-PWV), abdominal artery calcification calcaneus bone marrow density.Serum level was significantly elevated with arterial stiffness. Univariate correlation showed correlated intact parathyroid hormone cf-PWV density. Multiple linear regression analysis ≤300 pg/ml that pressure, logAACs...
Crescent formation indicates severe glomerular pathology, and hypothyroidism usually predicts poor prognosis for diseases. However, the relationship between thyroid function progression of chronic kidney disease (CKD) is unclear. This study analysed prognostic predictive value serum free triiodothyronine (FT3) to thyroxine (FT4) ratio its correlation with renal in patients CKD crescent formation.This single-centre included 162 crescents confirmed by pathology March 2012 December 2014....
Background Coal workers' pneumoconiosis (CWP) is characterized by progressive pulmonary fibrosis. Inflammation crucial in the host response to silica and it contributes Cyclooxygenase‐2 involved this process. The association between single‐nucleotide polymorphisms cyclooxygenase‐2 gene with risk was investigated. Methods An study conducted analyzing two of (rs689466 rs20417) a case–control involving 90 patients healthy individuals (controls). Genotyping performed TaqMan method. Results...
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma. Conventional chemotherapy (CHOP: cyclophosphamide, doxorubicin, vincristine, prednisone) seems unsatisfactory, so modifications CHOP are used to improve efficacy. DLBCL a highly variable tumor, with different responses therapy. The aim this study explore association between immunophenotype and treatment response. Patients Methods: We analyzed expression Bcl-6, CD10, MUM1 in 130 cases using...
BackgroundRBM10 is commonly mutated in lung adenocarcinoma (LUAD). However, its role the pathogenesis of LUAD remains undefined. EGFR-mutant represents a distinct subset non-small cell cancer (NSCLC). The function RBM10 tumor supposed to differ between and EGFR-wt LUAD. This study aimed interrogate prevalence mutation large cohort Chinese patients with investigate association clinical molecular characteristics LUAD.MethodsTumor sequencing data from 2,848 were retrospectively reviewed...
SMARCA4-deficient non-small cell lung cancer (NSCLC) is a more recently recognized subset of NSCLC. We describe the 18F-fluorodeoxyglucose (FDG) PET/CT findings in rare case NSCLC and response to therapy. A 45-year-old male patient with history heavy smoking (10 years) underwent an dynamic (chest) + static (whole-body) scan for diagnosis pre-treatment staging. 18F-FDG showed FDG-avid mass upper lobe left (SUVmax 22.4) lymph nodes (LN) pulmonary hilar region 5.7). In addition, there are...
Immune checkpoint inhibitors (PD-1/PD-L1 and CTLA-4 blockade) have revolutionized the treatment landscape in non-small cell lung cancer (NSCLC). Secondary resistance to immunotherapy (IO), which poses a substantial challenge clinical settings, occurs several initial responders. Currently, new approaches been extensively evaluated investigational studies for these patients tackle this difficult problem; however, lack of consistency definition, uniform criteria enrollment trials,...
Objective To explore the relationship between serum sclerostin level, and mineral metabolism, bone density, abdominal aortic calcification in maintenance hemodialysis (MHD) patients. Methods Serum levels from 175 cases of MHD patients were measured by ELISA. Calcaneus density (BMD) was quantitative ultrasound (QUS). The detected abdomen lateral plain radiographs. Interrelations among above parameters examined statistically. Results The median concentration 160.50(100.67, 256.39)...