A5049234033- HIV-related health complications and treatments
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Gout, Hyperuricemia, Uric Acid
- Alcohol Consumption and Health Effects
- Advanced Photonic Communication Systems
- HIV/AIDS drug development and treatment
- Optical Network Technologies
- Health disparities and outcomes
- Liver Disease Diagnosis and Treatment
- Advanced Optical Network Technologies
- Chronic Kidney Disease and Diabetes
- Global Health Care Issues
- Diabetes, Cardiovascular Risks, and Lipoproteins
- HIV, Drug Use, Sexual Risk
- Diet, Metabolism, and Disease
- Acute Kidney Injury Research
- Photonic and Optical Devices
- Viral Infections and Immunology Research
- Healthcare Systems and Reforms
- Birth, Development, and Health
- Renal Diseases and Glomerulopathies
- Gut microbiota and health
- Cardiovascular Health and Risk Factors
- Diet and metabolism studies
Tongren Hospital
2025
Shanghai Jiao Tong University
2025
Hunan Normal University
2019-2025
Zhongshan Hospital
2021-2024
Fudan University
2019-2024
Jiangnan University
2024
Shanghai Blood Center
2021-2024
The First Affiliated Hospital, Sun Yat-sen University
2022-2024
Sun Yat-sen University
2022-2024
Beijing University of Civil Engineering and Architecture
2023
Background The burden of gout is increasing worldwide, which places a heavy on society and healthcare systems. This study investigates the independent effects age, period, cohort prevalence from 1990 to 2019 in China, compares these by gender then predicts future over next decade. Methods data were obtained Global Burden Disease (GBD) 2019. Joinpoint regression model was employed calculate annual percentage change (APC) prevalence, age-period-cohort analysis utilized estimate cohort. ARIMA...
The goal of this study was to assess risk factors associated with HIV/AIDS progression. Between May 2007 and December 2014, 114 subjects were enrolled in Wuxi City examined every 6 months. pol gene sequence amplified ascertain the HIV-1 subtype. A Cox proportional hazards regression model used estimate median follow-up time for all 26.70 months (IQR: 18.50-41.47), while progression 38 progressed 24.80 14.13-34.38). Overall, CRF01_AE subtype correlated a significant accelerated compared...
We experimentally transmit eight wavelength-division-multiplexing (WDM) channels, 16 quadratic-amplitude-modulation (QAM) signals at 32-GBaud, over 1000 km few mode fiber (FMF). In this experiment, we use WDM, division multiplexing, and polarization multiplexing for signal transmission. Through the multiple-input–multiple-output (MIMO) equalization algorithms, achieve total line transmission rate of 4.096 Tbit/s. The results prove that bit error rates (BERs) 16QAM after FMF are below...
We disclose herein a chiral phosphoric-acid-catalyzed enantioselective addition reaction of alcohols to fluoroalkylated biaryl 1,3-oxoazepines, which furnished wide range bridged biaryls bearing quaternary carbon stereocenter on the seven-membered ring in high yields (up 99%) with excellent enantioselectivities 98% ee). Our method can be used for modification several natural products and bioactive molecules. Preliminary studies revealed that obtained this exhibit good vitro bioactivities...
Carotenoids possess essential antioxidant and anti-inflammatory properties; however, the relationships between carotenoids osteoarthritis or degenerative arthritis (OA) remain inadequately understood. This study aimed to investigate correlation diverse serum carotenoid concentrations OA in a large American cohort examine influence of various factors on association OA. Data from 2001–2006 2017–2018 National Health Nutrition Examination Surveys were utilized. In our analysis, we utilized...
Background: There is limited evidence on the relationship between social isolation and renal outcomes. To address this gap, study estimated prospective of with rapid kidney function decline development chronic disease (CKD) in middle-aged elderly Chinese normal function. Methods: We analyzed data from 3,031 participants aged ≥ 45 years baseline glomerular filtration rates (eGFR) 60 ml/min/1.73 m2. All were obtained 2011 2015 waves Longitudinal Study Health Retirement (CHARLS). eGFR was based...
Alcohol consumption is a major threat to global health. The aim of the present study was explore association between alcohol and chronic kidney disease (CKD) in Chinese population.A total 4664 participants, aged ≥18 years, who participated baseline survey 1997 were followed up 2009 China Health Nutrition Survey (CHNS), recruited current study. Data on obtained using standardized questionnaires, with CKD (defined as eGFR <60 mL/min/1.73 m2) outcome. results showed that 37.3% participants had...
HIV infection and normal aging share immune inflammatory changes that result in premature non-communicable diseases (NCDs), but the exact pathophysiology is not yet uncovered. We identified common metabolic pathways underlying various NCDs treated infection.We performed untargeted metabolomics including 87 HIV-negative (-) controls (NCs), HIV-positive (+) NCs, 148 HIV+ subjects with only one type of NCDs, namely, subclinical carotid atherosclerosis, neurocognitive impairment (NCI), liver...
Abstract Background We aimed to explore the association between long-term drinking behavior change patterns with hyperuricemia (HUA) in Chinese community adults. Methods This study was designed as a community-based unbalanced cohort involving 4127 adults aged 18 ~ 75 years, derived from China Health and Nutrition Survey (CHNS) 1997 2009. Drinking were categorized into: never drinking, quitting continued drinking. The alcoholism, type, frequency of further categorized. applied logistic...
Introduction Hypertension and rising serum uric acid (sUA) played a pivotal role in the development of Chronic Kidney Disease (CKD). This study investigates interactive effect sUA hypertension on CKD identifies optimal threshold among individuals with without Chinese community population.
Abstract Background Variation in the relationship between education and health has been studied intensely over past few decades. Although there is research on gender disparity cohort variations educational effect using samples from U.S. Europe, about China’s limited. Given specific social changes China, our study designed to analyze patterns education-health gradient. Method The latent growth-curve modeling was used gradient self-rated among Chinese respondents. employed longitudinal...
Gut microbiota dysbiosis has been associated with many neurological diseases. However, how composition and metabolism relate to neurocognitive impairment (NCI) in HIV-infected individuals is largely unknown. In this study, a total of 102 HIV infected participants were classified into two groups—those NCI those without—using the global deficit score (GDS). Fecal samples collected from for 16S rRNA gene sequencing untargeted metabolomics. The plasma level 25 hydroxy-vitamin D (25(OH)D) was...
In this study, we applied a composite index of neutrophil-lymphocyte * platelet ratio (NLPR), and explore the significance dynamics perioperative NLPR in predicting cardiac surgery-associated acute kidney injury (CSA-AKI).During July 1st December 31th 2019, participants were prospectively derived from 'Zhongshan Cardiovascular Surgery Cohort'. was determined using neutrophil counts, lymphocyte count at two-time points. Dose-response relationship analyses to delineate non-linear odds (OR)...
Based on the admission data, we applied XGBoost algorithm to create a prediction model estimate AKI risk in patients with hepatobiliary malignancies and then compare its capacity logistic model.We reviewed clinical data of 7968 589 liver/gallbladder cancer admitted Zhongshan Hospital during 2014 2015. They were randomly divided into training set test set. Data collected from electronic medical record system. LASSO-logistic used develop models, respectively. The performance measures included...
The terahertz photonics technique has bright application prospects in future sixth-generation (6G) broadband communication. In this study, we have experimentally demonstrated a photonics-assisted record-breaking net bit rate of 417 Gbit/s per wavelength signals delivery fiber-wireless converged communication system supported by advanced digital-signal-processing (DSP) algorithms and polarization multiplexing-based multiple-input multiple-output (MIMO) scheme. the experiment, up to 60 GBaud...
The prevalence and incidence of human immunodeficiency virus type 1 (HIV-1) among men who have sex with (MSM) are on the rise throughout China. With a large population MSM, Jiangsu Province is facing an escalating HIV-1 epidemic. aim this study was to explore phylogenetic temporal dynamics CRF01_AE CRF07_BC antiretroviral therapy (ART)-naïve MSM recently infected in Province. We recruited (Suzhou, Wuxi, Nantong, Taizhou Yancheng) 2012 2015. collected information demographics sexual behaviors...
Neurocognitive impairment (NCI) and gut microbiota dysbiosis are prevalent in patients with HIV infection. Docosahexanoic acid (DHA) supplementation may alleviate multiple neurocognitive diseases symptoms plays important role regulating microbiota. However, it is not known whether DHA algae oil supplements can regulate fecal metabolites. A randomized, double-blind, placebo-controlled trial was performed on 68 HIV-infected NCI. Participants were randomized to receive a 3.15 g daily supplement...
Introduction The question of whether the increased burden chronic kidney disease (CKD) is caused by interaction hyperuricemia and cardiovascular (CVD) risk factors or accelerated aging remains unresolved. purpose this study to better understand effect modification hyperuricemia, risk, age on CKD among Chinese population. Methods This cross-sectional 8243 participants was derived from China Health Nutrition Survey (CHNS) in 2009. Inclusion criteria included ≥18 years, non-pregnancy, no...
Abstract Objective To systemically examine the concomitant impact of adiposity indices on hypertension in children and adolescents. Methods A community-based cohort study by China Health Nutrition Survey (2009-2011) included 262 adolescents aged 7-17. Anthropometric lipid profiles were analyzed for risk using logistic cross-lagged models. Results Of 227 participants (mean age, 16.5 [2.3] years), 147 (53.9%) boys. Over a two-year period, 26.4% developed hypertension, 5.3% had elevated...