A5056109933- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Particle Detector Development and Performance
- Dark Matter and Cosmic Phenomena
- Cosmology and Gravitation Theories
- Computational Physics and Python Applications
- Neutrino Physics Research
- Black Holes and Theoretical Physics
- Astrophysics and Cosmic Phenomena
- Radiation Detection and Scintillator Technologies
- Rheumatoid Arthritis Research and Therapies
- Osteoarthritis Treatment and Mechanisms
- Medical Imaging Techniques and Applications
- Particle Accelerators and Free-Electron Lasers
- Systemic Lupus Erythematosus Research
- Magnetic Properties of Alloys
- Atomic and Subatomic Physics Research
- Vasculitis and related conditions
- Distributed and Parallel Computing Systems
- Stochastic processes and financial applications
- Rare-earth and actinide compounds
- Cold Atom Physics and Bose-Einstein Condensates
- Statistical Methods in Clinical Trials
- Quantum optics and atomic interactions
Université de Strasbourg
2016-2025
Institut Pluridisciplinaire Hubert Curien
2016-2025
Centre National de la Recherche Scientifique
2016-2025
Institute of High Energy Physics
2013-2024
A. Alikhanyan National Laboratory
2014-2024
Laboratoire de physique des lasers
2015-2024
Sorbonne Université
2006-2024
Université Sorbonne Paris Nord
2006-2024
University of Antwerp
1990-2024
Stanford University
2007-2023
Abstract The revised criteria for the classification of rheumatoid arthritis (RA) were formulated from a computerized analysis 262 contemporary, consecutively studied patients with RA and control subjects rheumatic diseases other than (non‐RA). new are as follows: 1) morning stiffness in around joints lasting at least 1 hour before maximal improvement; 2) soft tissue swelling (arthritis) 3 or more joint areas observed by physician; 3) proximal interphalangeal, metacarpophalangeal, wrist...
Abstract For the purposes of classification, it should be specified whether osteoarthritis (OA) knee is unknown origin (idiopathic, primary) or related to a known medical condition event (secondary). Clinical criteria for classification idiopathic OA were developed through multicenter study group. Comparison diagnoses included rheumatoid arthritis and other painful conditions knee, exclusive referred paraarticular pain. Variables from history, physical examination, laboratory tests,...
Abstract Objective. To standardize outcome measures in systemic lupus erythematosus (SLE). Three indices were identified which could adequately describe (disease activity, damage from disease, and health status); we here the development of Disease Activity Index. Methods. Twenty‐four variables as important factors a disease activity index. These used to generate 574 patient profiles, rated on scale 0–10 by 14 rheumatologists. A second rating 10 profiles yielded scores that not significantly...
Abstract Clinical criteria for the classification of patients with hip pain associated osteoarthritis (OA) were developed through a multicenter study. Data from 201 who had experienced most days prior month analyzed. The comparison group other causes pain, such as rheumatoid arthritis or spondylarthropathy. Variables medical history, physical examination, laboratory tests, and radiographs used to develop different sets serve investigative purposes. Multivariate methods included traditional...
Abstract Criteria for the classification of giant cell (temporal) arteritis were developed by comparing 214 patients who had this disease with 593 other forms vasculitis. For traditional format , 5 criteria selected: age ≥50 years at onset, new onset localized headache, temporal artery tenderness or decreased pulse, elevated erythrocyte sedimentation rate (Westergren) mm/hour, and biopsy sample including an artery, showing necrotizing arteritis, characterized a predominance mononuclear...
Abstract Criteria for the classification of Takayasu arteritis were developed by comparing 63 patients who had this disease with 744 control other forms vasculitis. Six criteria selected traditional format : onset at age ≤40 years, claudication an extremity, decreased brachial artery pulse, >10 mm Hg difference in systolic blood pressure between arms, a bruit over subclavian arteries or aorta, and arteriographic evidence narrowing occlusion entire its primary branches, large proximal...
Abstract Criteria for the classification of Churg‐Strauss syndrome (CSS) were developed by comparing 20 patients who had this diagnosis with 787 control other forms vasculitis. For traditional format , 6 criteria selected: asthma, eosinophilia >10% on differential white blood cell count, mononeuropathy (including multiplex) or polyneuropathy, non‐fixed pulmonary infiltrates roentgenography, paranasal sinus abnormality, and biopsy containing a vessel extravascular eosinophils. The presence...
Abstract Criteria for the classification of Wegener's granulomatosis (WG) were developed by comparing 85 patients who had this disease with 722 control other forms vasculitis. For traditional format , 4 criteria selected: abnormal urinary sediment (red cell casts or >5 red blood cells per high power field), findings on chest radiograph (nodules, cavities, fixed infiltrates), oral ulcers nasal discharge, and granulomatous inflammation biopsy. The presence 2 more these was associated a...
Abstract Objective . To determine the risk and causes of death to quantify mortality predictors in patients with rheumatoid arthritis (RA). Methods RA (n = 3,501) from 4 centers (Saskatoon n 905, Wichita 1,405, Stanford 886, Santa Clara 305) were followed for up 35 years; 922 died. Results The overall standardized ratio (SMR) was 2.26 2.24, 1.98, 3.08, 2.18) increased time. Mortality strikingly specific causes: infection, lymphoproliferative malignancy, gastroenterologic, RA. In addition, as...
Criteria for the classification of polyarteritis nodosa were developed by comparing 118 patients who had this disease with 689 control other forms vasculitis. For traditional format classification, 10 criteria selected: weight loss greater than or equal to 4 kg, livedo reticularis, testicular pain tenderness, myalgias, mononeuropathy polyneuropathy, diastolic blood pressure 90 mm Hg, elevated urea nitrogen serum creatinine levels, presence hepatitis B reactants in serum, arteriographic...
Abstract Clinical criteria for the classification of symptomatic idiopathic (primary) osteoarthritis (OA) hands were developed from data collected in a multi‐center study. Patients with OA compared group patients who had hand symptoms other causes, such as rheumatoid arthritis and spondylar‐thropathies. Variables medical history, physical examination, laboratory tests, radiographs analyzed. All pain, aching, or stiffness hands. classified having clinical if on examination there was hard...
A sample size calculation for logistic regression involves complicated formulae. This paper suggests use of formulae comparing means or proportions in order to calculate the required a simple model. One can then adjust multiple model by variance inflation factor. method requires no assumption low response probability as previous publication. similarly linear models. also compares accuracy some existing sample-size software with computer power simulations. An example illustrates methods. ©...
Abstract Criteria for identifying Henoch‐Schönlein Purpura (HSP) and distinguishing HSP from other forms of systemic arteritis were developed by comparing the manifestations in 85 patients who had with those 722 control vasculitis. By traditional format choosing different combinations candidate criteria their ability to separate cases controls, 4 identified: age ≤20 years at disease onset, palpable purpura, acute abdominal pain, biopsy showing granulocytes walls small arterioles or venules....
Background —The purpose of this study was to evaluate the safety and efficacy a temperature-controlled radiofrequency catheter ablation system. Methods Results patient population included 1050 patients who had undergone atrioventricular nodal reentrant tachycardia (AVNRT), an accessory pathway (AP), or junction (AVJ). Ablation successful in 996 patients. The probability success highest among AVJ, lowest AP, between for AVNRT. A major complication occurred 32 Four variables predicted (AVJ,...
<b>Background:</b> The relation between knee meniscal structural damage and cartilage degradation is plausible but not yet clearly proven. <b>Objectives:</b> To quantitate the volume changes in osteoarthritis using magnetic resonance imaging (MRI), determine whether alteration predicts loss over time. <b>Methods:</b> 32 patients meeting ACR criteria for symptomatic were studied. MRI acquisitions done every six months two years. volumes of different regions measured. Three indices change...
We report the observation of X(3872) in J/psipi(+)pi(-) channel, with J/psi decaying to mu(+)mu(-), pp collisions at sqrt[s]=1.96 TeV. Using approximately 230 pb(-1) data collected Run II D0 detector, we observe 522+/-100 candidates. The mass difference between state and is measured be 774.9+/-3.1(stat)+/-3.0(syst) MeV/c(2). have investigated production decay characteristics find them similar those psi(2S) state.
The factors associated with mortality were examined in a prospective longitudinal study, over an average of 12 years, 94% followup patients diagnosed as having rheumatoid arthritis. Of 805 patients, 233 died during the period study. Survivorship arthritis was approximately 50% less than that population controls. decreased by traditional demographic variables greater age and male sex; however, significant independent effect reflecting disease severity (American Rheumatism Association...
To determine the neurocognitive effects of continuous positive airway pressure (CPAP) therapy on patients with obstructive sleep apnea (OSA).The Apnea Positive Pressure Long-term Efficacy Study (APPLES) was a 6-month, randomized, double-blind, 2-arm, sham-controlled, multicenter trial conducted at 5 U.S. university, hospital, or private practices. Of 1,516 participants enrolled, 1,105 were and 1,098 diagnosed OSA contributed to analysis primary outcome measures.Active sham CPAP MEASUREMENTS:...
We evaluated methods of grading radiologic progression osteoarthritis (OA). Sets radiographs were assessed separately by 8 readers who blinded to the time sequence. Included patients with OA hands (24 pairs), hips (40 and knees (32 pairs). Most films taken 12-60 months apart. The relative contribution individual joints (such as particular interphalangeal joints), observations narrowing or spurs), a single joint compartment medial lateral knee) toward evidence was evaluated, well reliability...