A5082633221- Neurological disorders and treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Spine and Intervertebral Disc Pathology
- Cerebrospinal fluid and hydrocephalus
- Spinal Fractures and Fixation Techniques
- Epilepsy research and treatment
- Neurosurgical Procedures and Complications
- Meningioma and schwannoma management
- Spinal Hematomas and Complications
- Musculoskeletal pain and rehabilitation
- Neuroscience and Neural Engineering
- Vascular Malformations Diagnosis and Treatment
- Parkinson's Disease Mechanisms and Treatments
- Anesthesia and Pain Management
- EEG and Brain-Computer Interfaces
- Spinal Cord Injury Research
- Scoliosis diagnosis and treatment
- Spinal Dysraphism and Malformations
- Transcranial Magnetic Stimulation Studies
- Pain Management and Opioid Use
- Pituitary Gland Disorders and Treatments
- Olfactory and Sensory Function Studies
- Cervical and Thoracic Myelopathy
- Opioid Use Disorder Treatment
Allegheny General Hospital
2007-2025
Allegheny Health Network
2018-2024
Neurological Surgery
2015-2024
Neurosciences Institute
2023
St. Joseph's Hospital and Medical Center
2016-2021
Barrow Neurological Institute
2016-2021
Cleveland Clinic
2021
Temple University
2018
Jefferson Hospital for Neuroscience
2014-2015
Thomas Jefferson University
2012-2015
OBJECT Flow diverters are increasingly used for treatment of intracranial aneurysms. In most series, the Pipeline Embolization Device (PED) was large, giant, complex, and fusiform Little is known about use PED in small The purpose this study to assess safety efficacy aneurysms (≤ 7 mm). METHODS A total 100 consecutive patients were treated with at authors' institution between May 2011 September 2013. Data on procedural retrospectively collected. RESULTS mean aneurysm size 5.2 ± 1.5 mm. Seven...
The pipeline embolization device (PED) has been used for treatment of unruptured aneurysms. Little is known about the use PED in ruptured aneurysms.To assess safety and efficacy intracranial aneurysms.This a case series with prospective data collection on 20 patients freshly aneurysms who were treated (with or without adjunctive coiling) at 2 cerebrovascular centers. Patients loaded aspirin clopidogrel received an infusion tirofiban intraoperatively.Hunt Hess grades I 7 (35%), II 9 (45%),...
Lateral lumbar interbody fusion (LLIF) is a useful minimally invasive technique for achieving anterior and preserving or restoring lordosis. However, circumferential via posterior instrumentation after an LLIF can be challenging, requiring either repositioning the patient placing pedicle screws in lateral position. Here, authors explore alternative single-position approach: prone (PL) position.A cadaveric feasibility study was performed using 2 human specimens. A retrospective 2-center early...
Abstract Objective. Transcranial electrical stimulation (TES) is an effective technique to modulate brain activity and treat diseases. However, TES primarily used stimulate superficial regions unable reach deeper targets. The spread of injected currents in the head affected by volume conduction additional spreading as they move through layers with different conductivities, discussed [1]. In this paper, we introduce DeepFocus, a aimed at stimulating deep structures brain’s “reward circuit”...
The use of flow-diversion to treat ophthalmic segment aneurysms (OSA) has not been well evaluated.To assess the visual outcomes, obliteration rate, and need for retreatment OSA treated by pipeline embolization device (PED).Patients who underwent treatment with PED from 2009 2014 were selected retrospectively reviewed. Patient's age, sex, mode presentation, aneurysm size recorded. complication rates, (due recurrence or worsening symptoms), occlusion evolution symptoms, headache/retro-orbital...
Abstract BACKGROUND Multimodal analgesia regimens have been suggested to improve pain control and reduce opioid consumption after surgery. OBJECTIVE To institutionally implement an evidence-based quality improvement initiative standardize optimize treatment following neurosurgical procedures. Our goal was objectively evaluate efficacy of this multimodal protocol. METHODS A retrospective cohort analysis pain-related outcomes posterior lumbar fusion procedures performed. We compared patients...
Closed-suction drains are commonly placed after thoracolumbar surgery to reduce the risk of post-operative hematoma and neurologic deterioration, may stay in place for a longer period time if output remains high. Prolonged maintenance surgical site drains, however, is associated with an increased infection (SSI). The present study aims examine literature regarding extended duration (≥24 h) prophylactic antibiotic use patients undergoing posterior closed-suction drainage.
Abstract BACKGROUND Tethering after spinal surgery is caused by adhesions that arise from intradural tissue manipulation. Microsurgical detethering the only treatment for symptomatic patients, but retethering occurs commonly and no widely available to prevent this complication. OBJECTIVE To apply human amniotic membrane (HAM) grafts, which are immune-privileged known possess antifibrogenic properties, in patients requiring microsurgical detethering. For first-in-human use, we evaluated...
An advantage of lateral lumbar interbody fusion (LLIF) surgery is the indirect decompression neural elements that occurs because resulting disc height restoration, spinal realignment, and ligamentotaxis. The degree to which varies; no method exists for effectively predicting patients will respond. In this study, authors identify preoperative predictive factors central canal.
It is common practice to use a new contralateral bur hole for ventriculoperitoneal shunt (VPS) placement in subarachnoid hemorrhage (SAH) patients with an existing ventriculostomy. At Thomas Jefferson University and Hospital Neuroscience, the authors have primarily used ventriculostomy site VPS. The purpose of this study was compare safety 2 techniques SAH.The rates VPS-related hemorrhage, infection, proximal revision were compared between 523 undergoing VPS (same 464 59 patients).The rate...
Objective/Background This study aims to measure olfactory acuity in chronic migraine subjects, at baseline and on days, compare age‐ sex‐matched controls. Olfactory impairment is common neurological disorders. While smell hypersensitivity has been established with migraine, not well studied. Methods We recruited 50 subjects from the J efferson H eadache C enter Using U niversity of P ennsylvania S mell I dentification T est ( UPSIT ), a validated test olfaction, was measured during for...
Optimal postoperative pain control is critical after spinal fusion surgery. There remains significant variability in the use of intravenous opioid patient-controlled analgesia (PCA) and few data evaluating its utility compared with nurse-controlled (NCA) among patients lumbar fusion.To investigate efficacy PCA NCA to improve opiate prescription practices.A retrospective review from a single institution was conducted consecutive treated posterior for degenerative pathology. Patients were...