A5001616198- Cystic Fibrosis Research Advances
- Child Nutrition and Feeding Issues
- Thyroid Disorders and Treatments
- Gut microbiota and health
- Diet and metabolism studies
- Thyroid Cancer Diagnosis and Treatment
- Vitamin D Research Studies
- Pharmacology and Obesity Treatment
- Nutritional Studies and Diet
- Adolescent and Pediatric Healthcare
- Neonatal Respiratory Health Research
- Pregnancy and Medication Impact
- Breastfeeding Practices and Influences
- Respiratory and Cough-Related Research
- Health and Lifestyle Studies
- Tracheal and airway disorders
- Neuroscience of respiration and sleep
- Hair Growth and Disorders
- Pituitary Gland Disorders and Treatments
- Bariatric Surgery and Outcomes
- Dysphagia Assessment and Management
- Infant Nutrition and Health
- Infant Development and Preterm Care
- Pharmaceutical studies and practices
- Craniofacial Disorders and Treatments
Hospital Universitario Ramón y Cajal
2015-2025
Instituto Cajal
2023
Instituto Ramón y Cajal de Investigación Sanitaria
2020-2023
Universidad de Alcalá
2023
Vall d'Hebron Hospital Universitari
2021
Cystic Fibrosis Trust
2020
Hospital Regional Universitario de Málaga
1997-2013
Cork University Hospital
2013
University College Cork
2013
Instituto de Salud Carlos III
2011
The association between thyroid function during pregnancy and the later mental psychomotor development of child is supported by numerous experimental, clinical, epidemiological studies.The aim study was to evaluate psychological infants aged 3 18 months whose mothers had received 300 microg potassium iodide first trimester their compare with no iodine supplements.The included 133 women who 61 neuropsychological status children evaluated Bayley Scales Infant Development, measurements were...
The association between iodine deficiency and poor mental psychomotor development is known. However, most studies were undertaken in areas of very low intake. We investigated whether a similar found schoolchildren from southern Europe with median urinary output 90 μg/liter. Urinary levels measured 1221 children who also completed questionnaire about their usual dietary habits. Intelligence quotient (IQ) was by Cattell's g factor test. IQ significantly higher above 100 risk having an below...
Eur J Clin Invest 2011; 41 (11): 1202–1209 Background Different studies, mostly cross-sectional, have found an association between low levels of thyroid hormones, even within the normal range, and a greater body mass index. The aim this study was to determine function risk for obesity. Materials methods In population-based prospective study, measurements were made anthropometric parameters, hormone urinary iodine in cohort Pizarra Study (n = 937), repeated 6 years later 784). At second...
Abstract This is a prospective, multicenter study of cohort 224 cystic fibrosis (CF) patients treated with CF transmembrane conductance regulator (CFTR) modulators (CFTRm). Our aim was to prospectively analyze the effect CFTRm treatment on fat‐soluble vitamin serum levels. Demographic and clinical data were recorded, levels analyzed at baseline, 6 12 months after starting treatment. Two groups separately: receiving dual therapy lumacaftor/ivacaftor or tezacaftor/ivacaftor (Lum/Tez+Iva),...
Background Most patients with cystic fibrosis (CF) suffer from pancreatic insufficiency, leading to fat malabsorption, malnutrition and abdominal discomfort. Until recently, no specific tool was available for assessing gastro-intestinal related quality of life (GI QOL) in CF. As the Horizon2020 project MyCyFAPP aims improve GI QOL by using a newly designed mobile application, sensitive reliable outcome measure needed. We aimed study applicability existing child-specific Pediatric Quality...
The aim of this study was to monitor the impact a preoperative low-calorie diet and bariatric surgery on bacterial gut microbiota composition functionality in severe obesity compare sleeve gastrectomy (SG) versus Roux-en-Y gastric bypass (RYGB). also aimed incorporate big data analysis for omics results machine learning by Lasso-based detect potential markers excess weight loss. Forty patients who underwent were recruited (14 SG, 26 RYGB). Each participant contributed 4 fecal samples...
The aim of this study was to determine the relationship between auditory capacity and urinary iodine, taking into account thyroid volume function, in a population school-age children. Audiometry carried out 150 children (ages 6-14 years), together with measurements volume, thyrotropin (TSH), free T3, T4, thyroglobulin, antiperoxidase anti-TSH receptor antibodies, as well iodine casual urine sample. Children TSH >5 microU/mL were excluded from study. In palpable goiter, there an inverse...
Little information is available as to whether doses of iodide similar those recommended in clinical practice for the prevention iodine deficiency pregnant women affect thyroid function. The aim present study was analyse can function adults, and evaluate its effect on plasma markers oxidative stress, inflammation acute-phase proteins. A total thirty healthy volunteers (ten men twenty women) with normal were randomly assigned three groups ( n 10). Each group received a daily dose 100, 200 or...
Introduction: In recent years, guidelines for vitamin D supplementation have been updated and prophylactic recommended doses increased in patients with cystic fibrosis (CF). Objective: To evaluate safety efficacy of these new recommendations. Results: Two cohorts pancreatic insufficient CF were compared before (cohort 1: 179 patients) after 2: 71 American Foundation European Society recommendations published. Cohort 2 received higher Vitamin doses: 1509 (1306–1711 95% CI) vs 1084 (983–1184...
Provide data on a cross-sectional study of neurodevelopmental delays in positional plagiocephaly (PP) based severity and flattening side early childhood patients.
Objetives/Background: Vitamin D Binding Protein (VDBP) and free vitamin are new markers that being studied as a possible of status. The main aim our study was to analyse the VDBP genotype quantify levels in sample cystic fibrosis (CF) patients. Methods: Multicentre, cross-sectional prospective including patients with CF, exocrine pancreatic insufficiency who were clinically stable. We investigated (total free) different haplotypes. Free measured using an electro-chemiluminescence assay....
An increasing number of people are facing the burden obesity. Besides medical problems that related to obesity, reviewed literature shows this disease has become a social stigma affects health-related quality life obese people. The study focused specifically on how
Background A method to adjust Pancreatic Enzyme Replacement Therapy in Cystic Fibrosis is not currently available. Objectives To assess the vivo efficacy of a dose enzymatic supplement CF extrapolated from previous vitro digestion studies (theoretical optimal dose, TOD). Secondly, how individual patient characteristics influence expected coefficient fat absorption (CFA) and thus identify an correction factor improve TOD. Methods prospective interventional study 43 paediatric patients with 5...