A5100378525- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Circular RNAs in diseases
- Tendon Structure and Treatment
- Reproductive Biology and Fertility
- Mesenchymal stem cell research
- Burn Injury Management and Outcomes
- Brain Metastases and Treatment
- Advanced Image Fusion Techniques
- Sexual Differentiation and Disorders
- Immune Response and Inflammation
- Astrophysics and Star Formation Studies
- RNA Interference and Gene Delivery
- Advanced Image Processing Techniques
- Management of metastatic bone disease
- Cancer Genomics and Diagnostics
- Ovarian cancer diagnosis and treatment
- Cellular transport and secretion
- Esophageal Cancer Research and Treatment
- Seed Germination and Physiology
- Circadian rhythm and melatonin
- Nerve injury and regeneration
- Atomic and Molecular Physics
- Adipose Tissue and Metabolism
Anhui Provincial Hospital
2014-2024
Hainan Branch of People's Liberation Army General Hospital
2024
University of Science and Technology of China
2008-2024
Anhui Medical University
2014-2022
First Affiliated Hospital of Anhui Medical University
2022
The University of Texas MD Anderson Cancer Center
2022
Chongqing Academy of Animal Science
2019
Logistics University of People's Armed Police Force
2018
Tianjin University
2018
Jining First People's Hospital
2017
An increasing number of studies have demonstrated that some microRNAs participate in the regulation growth and development adipocytes. The present study shows microRNA-425-5p (miR-425) is a novel strong regulator adipogenesis adipolysis Forced expression miR-425 mice promoted body fat accumulation obesity due to high-fat intake, whereas silencing prevented from being obese. Mechanically, controlled by PPARγ during process MiR-425 overexpression resulted reduction proliferation 3t3-L1...
MicroRNAs (miRNAs) play an important role in the development and progression of human diseases. The identification disease-associated miRNAs will be helpful for understanding molecular mechanisms diseases at post-transcriptional level. Based on different types genomic data sources, computational methods miRNA-disease association prediction have been proposed. However, individual source tends to incomplete noisy; therefore, integration various inferring reliable associations is urgently...
One of the mechanisms by which cancer cells acquire hyperinvasive and migratory properties with progressive loss epithelial markers is epithelial-to-mesenchymal transition (EMT). We have previously reported that in different types, including nonsmall cell lung (NSCLC), microRNA-183/96/182 cluster (m96cl) highly repressed undergone EMT. In present study, we used a novel conditional m96cl mouse to establish accelerated growth Kras mutant autochthonous adenocarcinomas. contrast, ectopic...
Laboratory low-pressure cold plasma discharges, which are used to simulate some hot core environments in the star-forming region, have been investigated by employing single-photon vacuum ultraviolet (VUV) photoionization mass spectrometry. Enols with two four carbon atoms were detected discharges of alcohols, indicating that enols can result from alcohol destruction induced and cosmic radiation accelerated electrons abundant interstellar medium. This observation, together detection ethenol...
Melatonin (MT) can improve the effect of cryopreservation on oocytes by suppressing oxidative stress and maintaining permeability oolemma. In this study, MT was firstly applied to human oocytes’ explore prolonged developmental competence its role. Collected in vitro-matured were cryopreserved MT-containing or MT-free medium for 0 6 months; after warming, viable assessed viability, intracellular protein expression, mitochondrial function, oxidation-antioxidant system. Meanwhile, fresh set as...
Toll‑like receptors (TLRs) are expressed in human bone marrow‑derived mesenchymal stromal cells (BM‑MSCs), and the activation of TLRs is important proliferation, differentiation, migration hematopoiesis‑supporting functions BM‑MSCs. However, molecular mechanisms underlying these processes remain to be elucidated. MicroRNAs (miRNAs) involved various biological by mediating mRNA degradation or inhibiting translation target genes. The present study aimed identify whether regulate expression...
This study aimed to evaluate whether palliative surgery for metastatic lesion could provide a survival benefit in breast cancer (MBC) patients with solitary metastasis. De novo MBC distant lesions were enrolled utilizing the Surveillance, Epidemiology, and End Results (SEER) database. Propensity score matching (PSM) was conducted form matched pairs of group non-surgery group. The cancer-specific (BCSS) overall (OS) outcomes between 2 groups compared following 3 sample models: entire cohort...
// Jianjun Liu 1,* , Mingxue Su 2,* Jing Wang 3,* Gan Zhang 1 Zhou Anqing Zixue Ren Xucai Zheng Shikai Hong Shengying and Rongxin Department of Head - Neck Thoracic Surgery, Anhui Provincial Cancer Hospital, West branch Province Hefei, China 2 Infectious Disease Epidemiology, Lu’an People’s Lu’an, 3 Urologic * These authors have contributed equally to this work Correspondence to: Zhang, email: Wang, Keywords : neoadjuvant radiotherapy; gastric cancer; survival analysis;...
Abstract Background This study aimed to investigate the unique electroencephalography (EEG) patterns in neuronopathic Gaucher disease (GD) patients and explore correlations between EEG findings neurological phenotypes so as optimize clinical outcomes. Methods A retrospective analysis was conducted on 74 recordings from 50 GD January 2012 July 2022. Results Twenty-three exhibited abnormal recordings, including 11 of GD1 type (the transitional type) 12 with GD. Of patients, 9 epilepsy were...
Abstract Background: Developing biocompatible nerve conduits that accelerate peripheral regeneration, lengthening and functional recovery remains a challenge. The combined application of microtissues platelet-rich plasma (PRP) provides abundant Schwann cells (SCs) various natural growth factors can compensate for the deficiency SCs in bridge, as well limitations applying single type factor. Multimodal ultrasound evaluation provide additional information on stiffness microvascular flow...