A5013574663- Malaria Research and Control
- Patient-Provider Communication in Healthcare
- Immune responses and vaccinations
- Mosquito-borne diseases and control
- Healthcare Systems and Technology
- Patient Satisfaction in Healthcare
- Neonatal Respiratory Health Research
- Family and Patient Care in Intensive Care Units
- Drug-Induced Hepatotoxicity and Protection
- Infant Development and Preterm Care
- Diabetes Management and Research
- Immunodeficiency and Autoimmune Disorders
- Parasites and Host Interactions
- Vaccine Coverage and Hesitancy
- Computational Drug Discovery Methods
- Interprofessional Education and Collaboration
- Education, Healthcare and Sociology Research
- Innovations in Medical Education
- Child Nutrition and Water Access
- Respiratory viral infections research
- Empathy and Medical Education
- Adolescent and Pediatric Healthcare
- Healthcare Quality and Management
- Global Maternal and Child Health
- Social and Educational Sciences
University of Southern Denmark
2016-2025
Lillebaelt Hospital
2016-2025
Esbensen Consulting Engineers (Denmark)
2023
Bandim Health Project
2011-2022
Odense University Hospital
2015-2022
Kolding Hospital
2011-2021
Kiel University
2020
Indepth Network
2020
Statens Serum Institut
2008-2019
Norwegian Association for Development Research
2012-2017
Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the component partner drug. Polymorphisms in Plasmodium falciparum chloroquine resistance transporter ( pfcrt ) P. multidrug 1 pfmdr1 genes are associated with decreased sensitivity to amodiaquine lumefantrine, but effects of these polymorphisms therapeutic responses artesunate-amodiaquine (ASAQ) artemether-lumefantrine (AL) have not been clearly defined. Individual patient data from 31 trials were...
Introduction: Despite the knowledge of good communication as a precondition for optimal care and treatment in health care, serious problems are still experienced by patients well professionals. An orthopedic surgery department initiated 3-day skills training course all staff members expecting an increase patient-centeredness more respectful intercollegial communication. The aim this study was to investigate impact on participants' self-efficacy with focus both colleagues patients. Methods:...
The outcome of communication training is widely measured by self-efficacy ratings, and different questionnaires have been used. Nevertheless, none these formally validated through systematic measurement assessment properties. Consequently, we decided to further develop a questionnaire which has used in previous studies. This study aims examine the content, internal structure, relations with other variables new version (SE-12). was developed on basis theoretical approach applied course,...
Abstract Background and Hypothesis Maternal priming might enhance the beneficial nonspecific effects (NSEs) of live measles vaccination (MV). Children with a bacillus Calmette-Guérin (BCG) vaccine scar have lower mortality rate than those without that is not explained by protection against tuberculosis. We examined hypothesis BCG scarring would stronger effect on child if mother also had scar. Methods In randomized controlled trial (RCT) early MV in children aged 4.5 months, BCG-scar status...
Most healthcare professionals in neonatal intensive care units typically focus on the infants and mothers; fathers often feel powerless find it difficult to establish a father-child relationship. In family-centered settings, exploring fathers' experiences needs is important because men's roles society, especially as fathers, are changing.To describe when their admitted unit discuss these within theoretical framework of masculinity advance understanding generate meaningful knowledge for...
Genetic polymorphisms in P. falciparum can be used to indicate the parasite's susceptibility antimalarial drugs as well its geographical origin. Both of these factors are key monitoring development and spread drug resistance. In this study, we combine multiplex PCR, custom designed dual indexing Miseq sequencing for high throughput SNP-profiling 457 malaria infections from Guinea-Bissau, at cost 10 USD per sample. By amplifying 15 genetic fragments, cover 20 resistance-conferring SNPs...
Abstract Background The bacillus Calmette-Guérin (BCG) vaccine against tuberculosis might reduce the non–tuberculosis-related child mortality rate in low-income settings. We tested hypothesis that BCG vaccination at birth would early childhood hospitalization for infection Denmark, a high-income setting. Hospitalization was secondary outcome randomized trial with primary aim to estimate potential non-specific effects of on all-cause hospitalization. Methods A total 4262 children included...
Background The BCG vaccine is administered to protect against tuberculosis, but studies suggest there may also be non-specific beneficial effects upon the infant immune system, reducing early non-targeted infections and atopic diseases. present randomised trial tested hypothesis that vaccination at birth would reduce childhood hospitalisation in Denmark, a high-income setting. Methods Pregnant women planning give three Danish hospitals were invited participate. After parental consent,...
Healthcare professionals in neonatal intensive care units (NICUs) tend to focus attention on the mothers and newborn infants. Thus, fathers may find it difficult establish an optimal father-child relationship their stress increase persist during hospitalization.To investigate impact of a more father-friendly NICU paternal participation childcare.A quasiexperimental design was conducted Danish-speaking infants 28 or weeks' gestational age. The Parental Stressor Scale: Neonatal Intensive Care...
ABSTRACT Objective To investigate the effect of viral co‐infections on treatment length and failure in children with lower respiratory tract infections (LRTI) supported continuous positive airway pressure (CPAP) or high‐flow nasal cannula oxygenation therapy (HFNC). Methods Patients aged 0–5 years hospitalized LRTI need support between August 1 December 31, 2021, were retrospectively evaluated by patient chart audits. Results A total 148 (median age 10.1 [IQR 2.2–17.6] months) included. Of...
Abstract Aim Estimate the incidence of asthma among children aged 0 to 15 years in Denmark, Finland, Norway and Sweden during 2000–2017. Methods Cases preschool (up 6 years) school‐age (from were identified through national registers using an algorithm including hospital diagnoses prescription medicines. The respective cumulative (CI) was estimated 1‐year age intervals for each country birth year. Results CI algorithm‐based peaked cohorts 2008 or 2009 at 14.8% 11.0% 15.1% 13.7% Sweden. For...
In 2010 a communication program that included mandatory skills training for all employees with patient contact was developed and launched at large regional hospital in Denmark.We describe the program, implementation process, initial assessment of process to date.The cornerstone is course based on Calgary Cambridge Guide experiences several efficacy effectiveness studies conducted same hospital. The specific elements are described steps preliminary feedback from departments will be...
Background Childhood diarrhoea, a major cause of morbidity and mortality in low-income regions, remains scarcely studied many countries, such as Guinea-Bissau. Stool sample drying enables later qPCR analyses pathogens without concern about electricity shortages. Methods Dried stool samples children under five years treated at the Bandim Health Centre Bissau, Guinea-Bissau were screened by for nine enteric bacteria, viruses, four parasites. The findings having not diarrhoea compared age...
Summary Objective To describe the epidemiology of malaria in Guinea‐Bissau, view fact that more funds are available now for control country. Methods From May 2003 to 2004, surveillance was conducted among children less than 5 years age at three health centres covering study area Bandim Health Project (BHP) and outpatient clinic national hospital Bissau. Cross‐sectional surveys were community different seasons. Results Malaria overdiagnosed both hospital. Sixty‐four per cent who presented a...
In 2008, Guinea-Bissau introduced artemether-lumefantrine for treatment of uncomplicated malaria. Previously, 3 times the standard dose chloroquine, that was probably efficacious against Plasmodium falciparum with resistance-associated chloroquine-resistance transporter (pfcrt) 76T allele, routinely used. The present study compared efficacy and tolerability a double chloroquine artemether-lumefantrine.In randomized open-label clinical trial, or (50 mg/kg) were given as 6 divided doses over...
Rationale: Despite the fact that communication has become a core topic in health care, patients still experience information provided as insufficient or incorrect and lack of involvement. Objective: To investigate whether adult orthopaedic patients’ evaluation quality care had improved after skills training course for healthcare professionals. Design methods: The study was designed an intervention offering professionals communicating with colleagues. outcome measured by assessing care. Data...
To evaluate adverse reactions of the Bacillus Calmette–Guérin (BCG) Statens Serum Institut (SSI) (Danish strain 1331) used as intervention in a randomized clinical trial. A multicenter trial, The Danish Calmette Study, randomizing newborns to BCG or no intervention. Follow-up until 13 months age. Pediatric and maternity wards at three university hospitals. All women planning give birth study sites (n = 16,521) during recruitment period were invited participate study. Four thousand one...