A5029672818- Respiratory viral infections research
- Neonatal Respiratory Health Research
- Immune responses and vaccinations
- Vaccine Coverage and Hesitancy
- Immunodeficiency and Autoimmune Disorders
- Tracheal and airway disorders
- Congenital Diaphragmatic Hernia Studies
- Asthma and respiratory diseases
- Pneumonia and Respiratory Infections
- Child and Adolescent Health
- Virology and Viral Diseases
- SARS-CoV-2 and COVID-19 Research
- Infant Nutrition and Health
- Influenza Virus Research Studies
- Dermatology and Skin Diseases
- Pediatric health and respiratory diseases
- Ethics and Legal Issues in Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Allergic Rhinitis and Sensitization
- Streptococcal Infections and Treatments
- Ethics in Clinical Research
- Pericarditis and Cardiac Tamponade
- Adolescent and Pediatric Healthcare
- Infant Development and Preterm Care
- Viral Infections and Immunology Research
Copenhagen University Hospital
2016-2025
Rigshospitalet
2016-2025
University of Copenhagen
2012-2025
Capital Region of Denmark
2025
Statens Serum Institut
2008-2020
Bandim Health Project
2000-2015
University of Colorado Denver
2003-2014
Copenhagen Prospective Studies on Asthma in Childhood
2012
Gentofte Hospital
2012
Ophthalmology Clinic
2012
Observational studies have suggested that BCG may nonspecific beneficial effects on survival. Low-birth-weight (LBW) children are not given at birth in Guinea-Bissau; we conducted a randomized trial of (early BCG) vs delayed BCG.In the period 2004-2008 recruited 2320 LBW Bissau. The were visited home 2, 6, and 12 months age. With pretrial infant mortality 250 per 1000, hypothesized 25% reduction for children.Infant was only 101 1000 during trial. In primary analysis, reduced insignificantly...
Respiratory infections substantially impact pediatric health. The COVID-19 pandemic introduced widespread non-pharmaceutical interventions, which influenced the incidence of common respiratory infections. This comprehensive study investigates these interventions on syncytial virus, influenza, and invasive pneumococcal disease in Danish children. We conducted a descriptive based cohort 1,790,464 children from 2012 to 2022. analyzed data microbiology tests hospital contacts assess infection...
Severe respiratory syncytial virus (RSV) infection is associated with asthma but the nature of this association imperfectly understood.To examine between severe RSV and in a population-based sample twins.Data on hospitalization due to was gathered for all twins born Denmark 1994 2000 (8,280 pairs) linked information obtained from hospital discharge registries parent-completed questionnaires. Genetic variance components models direction causation were fitted observed data.RSV positively (r =...
Background. Little is known about how chronic conditions other than prematurity, heart disease, and Down syndrome affect the risk severity of hospitalization for respiratory syncytial virus (RSV). We assess RSV in children with this register-based, population-based cohort study. Methods. Data on tests, maternal smoking, siblings, single parenthood, mode delivery, gestational age at birth, major surgery, asthma diagnosis, conditions, discharge dates were obtained from Danish database,...
Abstract Objectives To assess the risk of acute and post-acute adverse events after SARS-CoV-2 infection in children adolescents Denmark to evaluate real world effectiveness BNT162b2 mRNA vaccine (Pfizer-BioNTech) among adolescents. Design Cohort study. Setting Nationwide Danish healthcare registers. Participants All people younger than 18 years who were either tested for using reverse transcriptase polymerase chain reaction (RT-PCR) or vaccinated with 1 October 2021. Main outcome measures...
Abstract Background The bacillus Calmette-Guérin (BCG) vaccine against tuberculosis might reduce the non–tuberculosis-related child mortality rate in low-income settings. We tested hypothesis that BCG vaccination at birth would early childhood hospitalization for infection Denmark, a high-income setting. Hospitalization was secondary outcome randomized trial with primary aim to estimate potential non-specific effects of on all-cause hospitalization. Methods A total 4262 children included...
Background The BCG vaccine is administered to protect against tuberculosis, but studies suggest there may also be non-specific beneficial effects upon the infant immune system, reducing early non-targeted infections and atopic diseases. present randomised trial tested hypothesis that vaccination at birth would reduce childhood hospitalisation in Denmark, a high-income setting. Methods Pregnant women planning give three Danish hospitals were invited participate. After parental consent,...
In this prospective nationwide multicenter study from Denmark, myopericarditis after Pfizer-BioNTech mRNA COVID-19 vaccination was identified in 13 males and 2 females between May 15 September 15, 2021, among 133,477 vaccinated 127,857 12–17 years of age, equaling 97 16 per million. conclusion, the incidence appears higher than reports United States.
Measles is a highly contagious viral disease. Vaccinated mothers transfer fewer antibodies during pregnancy, resulting in shortened infant immunity. Earlier primary vaccination might avert the gap protection.
This study examined whether atopic disposition, wheezing, and disorders increased the risk of hospitalizations because respiratory syncytial virus in children between birth 18 months age.Relative risks for hospitalization were studied a nested 1:5 case-control design using exposure information obtained from interviews with mothers 2564 case 12,816 control who had been followed prospectively until age as participants Danish National Birth Cohort. Information on children's ages at...
<h3>Aim</h3> To examine the relationship between birth weight and risk of asthma in a population twins. <h3>Methods</h3> Birth all live twins (8280 pairs) born Denmark 1994 2000 was linked to information on obtained from parent-completed questionnaires at age 3–9 years. Conditional logistic regression used calculate asthma. <h3>Results</h3> Subjects with history years weighed average 122 g (95% CI 85 160) less than subjects who had not developed asthma, p<0.001. There linear increase...
We estimated differences in the severity of respiratory syncytial virus infection attributable to genetic and environmental factors.Record linkage data on hospitalizations were gathered all twins (12,346 pairs) born Denmark between 1994 2003. Latent-factor models effects fitted observed by using maximal likelihood methods.Identical resembled each other significantly more than did fraternal for hospitalization (concordance rate: 0.66 vs 0.53), which suggests influences disease severity....
Background. Live vaccines may have nonspecific beneficial effects on morbidity and mortality. This study examines whether children who had the live-attenuated oral polio vaccine (OPV) as most recent a different rate of admissions for infectious diseases than with inactivated diphtheria-tetanus-pertussis-polio-Haemophilus influenzae type b (DTaP-IPV-Hib) or live measles-mumps-rubella (MMR) their vaccine. Methods. A nationwide, register-based, retrospective cohort 137 403 Danish born...
The aim of this study is to identify the risk factors for hospitalization respiratory syncytial virus (RSV) infection in Danish children.This a population-based cohort with follow-up till 24 months age. A total 421,943 children were divided into 5 groups based on gestational age (23-32, 33-35, 36, 37-41 and 42-45 weeks).In adjusted Cox regression models, chronic disease, asthma before RSV siblings associated an increased all independent Plurality was decreased born between 23 36 weeks...