A5086384315- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Cardiovascular Health and Risk Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Advanced Glycation End Products research
- Insect symbiosis and bacterial influences
- Lipoproteins and Cardiovascular Health
- Cytokine Signaling Pathways and Interactions
- Cancer Cells and Metastasis
- Cardiovascular Function and Risk Factors
- Eating Disorders and Behaviors
- Histone Deacetylase Inhibitors Research
- Ubiquitin and proteasome pathways
- Metal-Organic Frameworks: Synthesis and Applications
- Blood Pressure and Hypertension Studies
- Cardiovascular Disease and Adiposity
- Insect-Plant Interactions and Control
- Effects and risks of endocrine disrupting chemicals
- RNA Research and Splicing
- Dementia and Cognitive Impairment Research
- Heavy metals in environment
- Insect and Pesticide Research
- Genetic Associations and Epidemiology
- Renal Diseases and Glomerulopathies
- Trace Elements in Health
Shanghai East Hospital
2025
Soochow University
2023-2024
Center for Excellence in Molecular Plant Sciences
2022
Chinese Academy of Sciences
2022
Shanghai Normal University
2022
Collaborative Innovation Center of Advanced Microstructures
2021
Nanjing University
2021
Sun Yat-sen Memorial Hospital
2020
Sun Yat-sen University
2020
Summary Caterpillar oral secretion (OS) contains active molecules that modulate plant defense signaling. We isolated an effector‐like protein (Highly Accumulated Secretory Protein 1, HAS1) from cotton bollworm ( Helicoverpa armigera ) is the most highly accumulated secretory of nondigestive components in OS and belongs to venom R‐like protein. Elimination HAS1 by plant‐mediated RNA interference reduced suppression on response plants. Plants expressing are more susceptible insect herbivory...
Abstract Background Enolase 1 (ENO1) is a conserved glycolytic enzyme that regulates glycolysis metabolism. However, its role beyond in the pathophysiology of multiple myeloma (MM) remains largely elusive. Herein, this study aimed to elucidate function ENO1 MM, particularly impact on mitophagy under bortezomib-induced apoptosis. Methods The bone marrow clinical MM patients and healthy normal donors was used compare expression level ENO1. Using online databases, we conducted an analysis...
Although early detection and systemic therapies have improved the diagnosis clinical cure rate of breast cancer, cancer remains most frequently occurring malignant in women due to a lack sufficiently effective treatments. Thus, develop potential targeted thus benefit more patients, it is helpful understand how cells work. ZIC family members been shown play important roles neural development carcinogenesis. In our study, we found that ZIC2 downregulated tissues at both mRNA protein levels....
[Background] Metal exposure is suspected to be correlated kidney function. However, the combined effects of co-exposing multiple metals, especially both toxic and protective have not been completely evaluated. [Method] A prospective cohort study was conducted with “135” for evaluation how plasma metal levels are function in a midlife elderly community southern China. An amount 1368 subjects without disease at baseline were enrolled final analysis. By using linear regression logistic models,...
The interplay between cardiovascular health metrics (CVHMs) and microvascular disease (MVD) in relation to the risk of incident coronary heart (CHD) among individuals with type 2 diabetes mellitus (T2DM) remains be evaluated.
The relationship between coffee consumption and diabetes-related vascular complications remains unclear. To eliminate confounding by smoking, this study assessed the relationships of with major cardiovascular disease (CVD) microvascular (MVD) in never-smokers type 2 diabetes mellitus (T2DM). Included were 9964 T2DM from UK Biobank without known CVD or cancer at baseline (7781 free MVD). Participants categorized into four groups according to daily (0, 0.5–1, 2–4, ≥5 cups/day). included...
Wide phthalate exposure has been associated with both declines in renal function and an elevated risk of mortality. Whether phthalate-associated premature mortality differs by status remains unclear.
Lipoprotein(a) (Lp(a)) is a largely genetically determined biomarker for cardiovascular disease (CVD), while its potential interplay with family history (FHx) of CVD, measure both genetic and environmental exposures, remains unclear. We examined the associations Lp(a) in terms circulating concentration or polygenetic risk score (PRS), FHx CVD incident heart failure (HF). Included were 299,158 adults from UK Biobank without known HF at baseline. Hazards ratios (HRs) 95% Cls estimated by Cox...
Whether estimated glomerular filtration rates (eGFRs) by differing biomarkers are differentially associated with mortality or whether the associations differ diabetes status remains unclear, especially in Chinese population.We included 6995 participants without (mean age: 60.4 years) and 1543 61.8 years). Each eGFR measure was divided into normal (≥90 mL/min/1.73 m2 ), modestly declined (60 to <90 chronic kidney disease (CKD) (<60 ) groups. Cox proportional hazards models were used estimate...
Comprehensive Summary Three heteronuclear Ir III ‐Co II arrays, [Co(H 2 O) 6 ] [Ir(ppyCOO)(ppyCOOH)(bpy)] [Ir(ppyCOO) (bpy)] (NO 3 ) ⋅10.5H O (2), ]{Co(H 4 }[Ir(ppyCOO) ⋅15H (3) and {Co(H }⋅2CH OH⋅3H (4), have been synthesized by combining paramagnetic Co ion with luminescent ‐metalloligand, [Ir(ppyCOOH) (bpy)][Ir(ppyCOO) (bpy)]⋅5H (1), where ppyCOOH = 3‐(pyridin‐2‐yl)benzoic acid bpy 2,2'‐bipyridyl. Owing to the variable charged states of compound 1 at different pH, compounds are discrete...