- Acute Ischemic Stroke Management
- Inflammatory Biomarkers in Disease Prognosis
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Liver Disease Diagnosis and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cerebrovascular and Carotid Artery Diseases
- Diabetes Management and Research
- Obstructive Sleep Apnea Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipokines, Inflammation, and Metabolic Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sepsis Diagnosis and Treatment
- Mosquito-borne diseases and control
- Pulmonary Hypertension Research and Treatments
- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Studies
- Sleep and Wakefulness Research
- EEG and Brain-Computer Interfaces
- Traffic Prediction and Management Techniques
- Acute Kidney Injury Research
- Nitric Oxide and Endothelin Effects
- Atherosclerosis and Cardiovascular Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Diabetic Foot Ulcer Assessment and Management
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024
Beijing Hospital
2024
Southwest University
2023
Wenzhou Medical University
2008-2022
Ruian People's Hospital
2020-2021
Gansu University of Traditional Chinese Medicine
2017
Abstract Background The triglyceride–glucose (TyG) index, which is a reliable surrogate marker of insulin resistance (IR), has been associated with cardiovascular diseases. However, evidence the impact TyG index on severity coronary artery disease (CAD) limited. This study investigated relationship between and CAD individuals different glucose metabolic statuses. Methods enrolled 2792 participants in China January 1, 2018 December 31, 2021. All were divided into groups according to tertiles...
Stress hyperglycemia is strongly associated with poor clinical outcomes in patients acute coronary syndrome (ACS). Recently, the stress ratio (SHR) has been proposed to represent relative hyperglycemia. Studies regarding relationship between SHR and mortality artery disease (CAD) are limited. This study aimed clarify association in-hospital CAD. A total of 19,929 CAD who were hospitalized Beijing Hospital enrolled this study. Patients an estimated glomerular filtration rate < 30 ml/min,...
Systemic immune-inflammation index (SII), a novel inflammation derived from counts of circulating platelets, neutrophils and lymphocytes, has been studied in developing incident cancer. However, the clinical value SII acute ischemic stroke (AIS) patients had not further investigated. Therefore, we aimed to explore association between severity as well 3-month outcome AIS patients.A total 216 receiving intravenous thrombolysis (IVT) 875 healthy controls (HCs) were retrospectively recruited....
Stress hyperglycemia ratio (SHR), calculated as glucose/glycated hemoglobin, has recently been developed for assessing stress and could provide prognostic information various diseases. However, calculating SHR using random blood glucose (RBG) drawn on admission or fasting (FBG) lead to different results. This study intends evaluate the association between functional outcomes in patients with acute ischemic stroke (AIS) recombinant tissue plasminogen activator (r-tPA) intravenous...
Sleep is vital to human health, and sleep staging an essential process in assessment. However, manual classification inefficient task. Along with the increased demand for portable quality detection devices, lightweight automatic needs be developed.This study proposes a novel attention-based deep learning model called LWSleepNet. A depthwise separable multi-resolution convolutional neural network introduced analyze input feature map captures features at multiple frequencies using two...
Mounting researches have illuminated that the neutrophil-related ratios were related to prognosis of acute ischemic stroke (AIS). However, few compared their predictive value and accuracy. To make such comparison identify best indicator on 90-day outcome, we investigated biomarkers including neutrophil ratio (Nr), count (Nc), lymphocyte (L), neutrophil-to-lymphocyte (NLR), platelet (P or PLT), platelet-to-neutrophil (PNR), NLR-to-platelet (NLR/PLT), eosinophil (E), neutrophil-to-eosinophil...
Triglyceride-glucose (TyG) index, as an effective surrogate marker of insulin resistance, has shown predictive value in the risk heart failure patients with coronary artery disease (CAD). This study aims to investigate correlation between TyG index and myocardial work measurements CAD, explore its role detecting early subclinical cardiac dysfunction.
Background and Purpose Blood eosinophil counts are thought to be associated with atherosclerosis in acute ischemic stroke (AIS) AIS severity. We aimed investigate 1): the temporal profile of patients treated recombinant tissue plasminogen activator (r-tPA); 2): The association between dynamic 3-month outcomes different etiologies; 3): incremental predictive ability adding conventional model; 4): longitudinal change neutrophil-to-lymphocyte ratio (NLR) compared its prognostic value...
To observe the analgesic effect of acupuncture and to explore its central mechanism in rheumatoid arthritis rabbits. Methods: A total 60 flap-eared white rabbits were randomly assigned into a normal control group (n=6), model body-acupuncture (n=24), buccal (n=24). The later 2 groups further 0, 0.5, 1, h subgroups, with 6 cases each group. was established by induction egg-albumin. In body group, bilateral "Xiyan" "Zusanli" punctured for 15 s while applied "Xi" s, needle retaining 30 min....
Background and Purpose: The eosinophil-to-neutrophil ratio (ENR) was recently reported as a novel inflammatory marker in acute ischemic stroke (AIS). However, few studies the predictive value of ENR AIS patients, especially for those with intravenous thrombolysis. Methods: Two hundred sixty-six patients receiving thrombolysis were retrospectively recruited this study followed up 3 months 1 year. Modified Rankin Scale (mRS) time death recorded. Poor outcome defined mRS 3–6. After excluding...
We aimed to evaluate and compare the association between globulin albumin ratio (GAR) prealbumin (GPR) 3-month functional prognosis of acute ischemic stroke (AIS) patients receiving intravenous thrombolysis therapy.234 AIS undergoing were retrospectively enrolled with from February 2016 October 2019. Blood sample was collected within 24 h after admission. Poor outcome defined as modified Rankin Scale (mRS) ≥ 3 a favorable mRS < 3. Severe National Institutes Health Stroke (NIHSS) score > 10...
Objectives: To evaluate the efficacy of hydrocortisone in patients with septic acute kidney injury (SAKI).Methods: This retrospective cohort study consisted all consecutive SAKI who were admitted to Taizhou First People's Hospital from March 2016 February 2018. The treated usual care including antibiotics, fluid resuscitation, and blood glucose control regarded as group, those received add-on by clinicians' discretion was considered intervention group. Hydrocortisone administered a 50 mg...
Abstract Background: The triglyceride-glucose (TyG) index, as a reliable surrogate marker of insulin resistance, is independently associated with the prognosis cardiovascular diseases. This current study aimed to investigate relationship between TyG index and in-hospital all-cause mortality coronary artery disease (CAD) in patients different glucose metabolic statuses. Methods: enrolled 10 964 CAD China January 1, 2016 December 30, 2021. All were divided into groups according tertiles T1...
Abstract Background The red cell index (RCI) was described as a biomarker for evaluating respiratory function in previous studies, but the relationship between RCI and stroke, remained mystery. present study aimed to probe association at 24‐hr 3‐month mortality functional outcomes among acute ischemic stroke (AIS) patients treated with recombinant tissue plasminogen activator (r‐tPA). Methods A total of 217 AIS January 2016 2019 were recruited this retrospective study. grouped terms...
Background and Aims:To evaluate the efficacy safety of venlafaxine HCL sustained release capsules in treatment depression adolescents.Methods:A randomized,double blind double dummy clinical trial enrolled 60 adolescents patients with depression, who were randomized 1:1 to administer 150 mg or fluoxetine 20 daily for 8 weeks.The both groups was evaluated based on Hamilton Depression Scale Clinical General Impression pre- post-treatment.Results:The scores at end therapy significantly reduced...
Abstract BackgroundStress hyperglycemia manifests as transient in the context of illness with or without known diabetes, which may cause poor clinical outcome acute ischemic stroke (AIS) patients. The present study intended to evaluate association between stress ratio (SHR) and 1-year after treatment recombinant tissue plasminogen activator (r-tPA) for AIS patients compare predictive effect fasting glucose concentration, glycosylated hemoglobin (HbA1c) SHR. MethodsData from 205 following...
Abstract Background: Chronic obstructive pulmonary disease (COPD) has always attracted attention due to its high prevalence and mortality. How predict diagnose COPD assess the severity of is our top priority. We aimed evaluate association between red cell index (RCI) COPD, compare predictive value among RCI, neutrophil-lymphocyte ratio (NLR) platelet-lymphocyte (PLR) indicating COPD. Methods: A total 207 participants were recruited (100 patients 107 healthy controls). divided into two groups...