A5049430015- Hematopoietic Stem Cell Transplantation
- Pediatric health and respiratory diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Renal Diseases and Glomerulopathies
- Immunodeficiency and Autoimmune Disorders
- Neutropenia and Cancer Infections
- Childhood Cancer Survivors' Quality of Life
- Polyomavirus and related diseases
- Immune Response and Inflammation
- Adolescent and Pediatric Healthcare
- Immune cells in cancer
- EEG and Brain-Computer Interfaces
- Chronic Myeloid Leukemia Treatments
- Parasitic Infections and Diagnostics
- Bartonella species infections research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Transplantation: Methods and Outcomes
- Kruppel-like factors research
- Calcium signaling and nucleotide metabolism
- Chemotherapy-induced cardiotoxicity and mitigation
- Hepatitis B Virus Studies
- Insects and Parasite Interactions
- Mesenchymal stem cell research
- Antifungal resistance and susceptibility
- PARP inhibition in cancer therapy
Jagiellonian University
2006-2021
Uniwersytecki Szpital Dziecięcy
2006-2021
Chronic granulomatous disease (CGD) is phagocytic cell metabolic disorder resulting in recurrent infections and granuloma formation. This paper reports the favourable outcome of allogeneic transplantation six high-risk CGD patients. The following donors were used: HLA-matched, related (two) unrelated (three), HLA-mismatched, (one). One patient was transplanted twice using same sibling donor because graft rejection at 6 months after reduced-intensity conditioning transplant (fludarabine...
Total parenteral nutrition (TPN) is still of great importance for haematopoietic stem cell transplantation (HSCT) patients because one the major adverse effects high-dose therapy followed by HSCT an inadequate oral intake. The aim study was analysis TPN young in period. Twenty-two 1·8–20·8 year-old, median 5·4, treated with and autologous malignancy were included into study. Grafts contained 1·35–7·9 × 10 6 , 3·75 CD34 + cells/kg. Engraftment occurred as follows: granulocytes >0·5 9 /l on...
Visfatin (VF) is an adipocytokine that performs many functions, including enhancing cell proliferation and biosynthesis of nicotinamide mononucleotides dinucleotides. It also seems to be involved in the development glucose metabolism disturbances. The goal study was determination VF concentrations children with leukemia who are treated stem transplantation. were measured plasma before after oral tolerance test (OGTT; 60 120 minutes) 22 hematopoietic transplantation (HSCT) healthy control...
Abstract: OS is a variant of SCID characterized by generalized erythroderma, alopecia, eosinophilia, and elevated IgE levels. It fatal unless treated with allogeneic HSCT, which the only curative approach. However, treatment related complications graft rejection are major obstacles to success treatment. In this report, we describe patient OS, complicated prolonged cytomegalovirus infection, successfully reduced intensity conditioning HSCT from sibling donor.
Infections are still a major reason of morbidity and one the most common causes death after hematopoietic cell transplantation (HCT). Antimicrobial prophylaxis plays crucial role in decreasing non-relapse mortality HCT. The objective this guideline paper is presentation current recommendations antimicrobial for children adults transplantation, prepared cooperation Polish scientific hematological societies. Recommendations were by working group finally approved all 23 transplant centers...
Toxocariasis was diagnosed in 3 out of 22 children (14%) treated our center with high-dose chemotherapy and autologous hematopoietic stem cell transplantation (HSCT). The patients were coming from rural areas the southeastern Poland did not present any clinical symptoms toxocariasis upon admission to hospital. Although no neurological ophtalmological abnormalities noticed, atypical form toxacariasis based on elevated eosinophils counts, positive serological tests, biochemical liver damage....
Infections in immunocompromised patients after hematopoietic stem cell transplantation can have a severe and atypical course. Some opportunistic pathogens are difficult to detect microbiological tests, that is why treatment success depends on an accurate clinical diagnosis. This article presents case of 7-year-old girl with aplastic anemia treated bone marrow post-transplantation period complicated by persistent, hectic fever, peak episodes 39-40°C, lasting several weeks. Repeated tests...
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