A5051637122- Bladder and Urothelial Cancer Treatments
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Urinary and Genital Oncology Studies
- Prostate Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Prostate Cancer Treatment and Research
- Urological Disorders and Treatments
- Cancer Immunotherapy and Biomarkers
- Spinal Cord Injury Research
- Renal and related cancers
- Diversity and Career in Medicine
- Venous Thromboembolism Diagnosis and Management
- Single-cell and spatial transcriptomics
- Global Health Workforce Issues
- Brain Metastases and Treatment
- Cancer-related cognitive impairment studies
- Dementia and Cognitive Impairment Research
- Renal and Vascular Pathologies
- Advanced Neuroimaging Techniques and Applications
- Health and Wellbeing Research
- Multiple and Secondary Primary Cancers
- Nanoplatforms for cancer theranostics
- Tissue Engineering and Regenerative Medicine
- Immune cells in cancer
Harvard University
2018-2024
Massachusetts General Hospital
2018-2024
Brigham and Women's Hospital
2018-2024
Baylor College of Medicine
2023-2024
Beth Israel Deaconess Medical Center
2024
Stanford University
2012-2021
Stanford Medicine
2016-2021
VA Palo Alto Health Care System
2015-2019
Stanford Health Care
2018
Beijing Administration Institute
2018
The treatment of low-risk primary prostate cancer entails active surveillance only, while high-risk disease requires multimodal including surgery, radiation therapy, and hormonal therapy. Recurrence development metastatic remains a clinical problem, without clear understanding what drives immune escape tumor progression. Here, we comprehensively describe the microenvironment localized in comparison with adjacent normal samples healthy controls. Single-cell RNA sequencing high-resolution...
Intraoperative optical biopsy technologies may aid in the identification of important anatomical landmarks and improve surgical outcomes robotic assisted radical prostatectomy. We evaluate feasibility confocal laser endomicroscopy during prostatectomy.A total 21 patients with proven prostate cancer scheduled for prostatectomy were recruited. After intravenous administration fluorescein 15 underwent vivo intraoperative prostatic periprostatic structures using a 2.6 or 0.85 mm imaging probe....
White light endoscopy is widely used for diagnostic imaging of the interior organs and body cavities, but inability to correlate individual 2D images with 3D organ morphology limits its utility quantitative or longitudinal studies disease physiology cancer surveillance. As a result, most videos, which carry enormous data potential, are only real-time guidance discarded after collection. We present computational method reconstruct visualize model from an endoscopic video that captures shape...
Tissue diagnosis of upper tract urothelial carcinoma (UTUC) is limited by variance in tumor sampling standard ureteroscopic biopsy. Optical imaging technologies can potentially improve UTUC diagnosis, surveillance, and endoscopic treatment. We previously demonstrated vivo optical biopsy the bladder using confocal laser endomicroscopy (CLE). In this study, we evaluated a new 0.85-mm probe urinary feasibility compatibility with ureteroscopes to achieve UTUC.Fourteen patients scheduled for...
We analyzed structural magnetic resonance imaging data from 58 cognitively normal and 101 mild cognitive impairment subjects. used a general linear regression model to study the association between performance with hippocampal atrophy ventricular enlargement using radial distance method.<b><i></i></b>Bilateral was associated baseline longitudinal memory performance. Left predicted decline in visuospatial function. The multidomain analysis did not reveal any...
Purpose: Urology is one of the most competitive specialties for residency matches in United States. Data reported by American Urological Association from match cycles spanning 2014 to 2021 reveal a median 0.34% (0%-3%) unfilled spots, 1.48 (1.28-1.87) applicants per position, and 75% (63%-87%) rate. Recent research has shown that program directors value applicants' highly. We sought assess productivity matched urology applicants, identify trends volume over time, investigate potential...
Objective To examine the incidence of perioperative complications after radical cystectomy ( RC ) and assess their impact on 90‐day postoperative mortality during index stay upon readmission. Patients methods A total 57 553 patients with bladder cancer (unweighted cohort: 9137 patients) treated RC, at 360 hospitals in USA between 2005 2013 within Premier Healthcare Database, were used for analysis. The was primary outcome. Multivariable regression to predict probability mortality; models...
No AccessUrology PracticeUrology Practice Perspectives1 Mar 2024International Medical Graduates in Urology: Tracking Success Through Research David Eugenio Hinojosa-Gonzalez, Shane Kronstedt, Gal Saffati, Wesley A. Mayer, Ruslan Korets, Dimitar Zlatev, Anton Wintner, and Brian H. Eisner Hinojosa-GonzalezDavid Hinojosa-Gonzalez *Corresponding Author: MD, Scott Department of Urology, Baylor College Medicine, 7200 Cambridge St, Houston, TX 77030 ( E-mail Address: [email protected]...
We analyzed the baseline and 3-year T1-weighted magnetic resonance imaging data of 110 amnestic mild cognitive impairment (MCI) participants with minimal hippocampal atrophy at from Alzheimer’s Disease Cooperative Study group MCI Donepezil/Vitamin E trial. Forty-six subjects converted to Alzheimer disease (AD) (MCIc), whereas 64 remained stable (MCInc). used radial distance technique examine differences in lateral ventricle shape size between MCIc MCInc associations ventricular enlargement...
This study assesses the use of confocal laser endomicroscopy to diagnose and grade bladder cancer applied crowdsourcing determine barriers learning how using endomicroscopy.
In many individuals with spinal cord injury a return of volitional bladder voiding is considered more important than regaining motor function. Recently predictive model using only composite bilateral lower extremity scores for levels L2-S1 (range 0 to 50) was proposed by the EMSCI (European Multicenter Study about Spinal Cord Injury) group. The showed exceptional power an AUC 0.912. We sought further validate in national cohort.We created models United States NSCID (National Injury Database)...
Introduction Clean intermittent catheterization (CIC) is the gold standard for neurogenic bladder management in most patients with spinal cord injury (SCI). There nonetheless a lack of long‐term adherence to CIC, up 50% discontinuance at 5‐year follow‐up. We hypothesize that limitations upper extremity (UE) motor function represent strong predictor CIC adoption. Methods assessed Forms I and II data from 2000‐2013 National SCI Database. Bladder was determined initial discharge 1‐year Upper...
Three-dimensional (3D) organ-mimicking phantoms provide realistic imaging environments for testing various aspects of optical systems, including evaluating new probe designs, characterizing the diagnostic potential technologies, and assessing novel image processing algorithms prior to validation in real tissue.We introduce characterize use a material, Dragon Skin (Smooth-On Inc.), fabrication technique, air-brushing, 3D phantom that mimics appearance organ under multiple modalities.We...
The aim of this study was to characterize the demographics, usage patterns and complication rates clomiphene use in male patients.We retrospectively analyzed patients from ages 20 55 years old who were prescribed citrate 2001 2014 using Truven Health MarketScan, a US claims database. We collected data regarding associated medical diagnoses, diagnostic testing, duration use, reported side effects including thrombotic events, vision problems, gynecomastia, mental disorders, liver disease,...
Bladder dysfunction after spinal cord injury (SCI) often requires clean intermittent catheterization (CIC) or other management strategies. A common dilemma in those desiring to perform CIC independently but lacking the appropriate upper extremity (UE) motor function is timing of reconstructive surgery.We assessed National Spinal Cord Injury Data Set for years 2000-2016. Our cohort consisted persons with cervical SCI, who underwent complete examination upon discharge from rehabilitation and...
107 Background: A core tenant of major cancer society guidelines regarding prostate screening (PSAS) is that providers discuss both the advantages and disadvantages with eligible patients in a shared decision making (SDM) process. We sought to determine contemporary trends SDM regards PSAS. Methods: Consistent AUA for PSAS, data was abstracted from 2012-2016 Behavioral Risk Factor Surveillance System men 55-69, without personal history cancer, having answered all questions within PSAS...