- Radiomics and Machine Learning in Medical Imaging
- Water Treatment and Disinfection
- Chemical Analysis and Environmental Impact
- Ferroptosis and cancer prognosis
- Lung Cancer Diagnosis and Treatment
- Education and Work Dynamics
- Gastric Cancer Management and Outcomes
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- RNA Research and Splicing
- Educational Technology and Pedagogy
- Asian American and Pacific Histories
- Sexual function and dysfunction studies
- Vascular Malformations and Hemangiomas
- Korean Peninsula Historical and Political Studies
- Face Recognition and Perception
- Tuberculosis Research and Epidemiology
- Themes in Literature Analysis
- Infectious Diseases and Tuberculosis
- Matrix Theory and Algorithms
- Sexual Differentiation and Disorders
- Physical Education and Training Studies
- Misinformation and Its Impacts
- Educational Reforms and Innovations
- Inflammasome and immune disorders
Liupanshui Normal University
2006-2024
Lu'an First People's Hospital
2024
Anhui Medical University
2024
Xiangya Hospital Central South University
2024
Nanjing Drum Tower Hospital
2024
Central South University
2024
Aviation Industry Corporation of China (China)
2023
Guangxi Medical University
2010-2023
National University of Singapore
2023
Center for High Pressure Science & Technology Advanced Research
2021-2023
Brain invasion in meningioma has independent associations with increased risks of tumor progression, lesion recurrence, and poor prognosis. Therefore, this study aimed to construct a model for predicting brain WHO grade II by using preoperative MRI.One hundred seventy-three patients 111 without were included. Three mainstream features, namely, traditional semantic features radiomics from tumor-to-brain interface regions, acquired. Predictive models correspondingly constructed on each feature...
Abstract Purpose To investigate the application and effectiveness of tension-reducing suture in repair hypertrophic scars. Methods A retrospective analysis clinical data was conducted on 82 patients with scars treated at Department Burns Plastic Surgery Nanjing Drum Tower Hospital from September 2021 to December 2022. Patients were operated combination heart-shaped suturing technique looped, broad, deep buried (LBD) or conventional method. Outcomes surgical treatment assessed before 6 months...
We established and evaluated a radiomics nomogram based on multislice computed tomography (MSCT) arterial phase contrast-enhanced images to distinguish between Crohn's disease (CD) ulcerative colitis (UC) objectively, quantitatively, reproducibly.MSCT phase-enhancement of 165 lesions (99 CD, 66 UC) in 87 patients with inflammatory bowel (IBD) confirmed by endoscopy or surgical pathology were retrospectively analyzed. A total 132 (80%) selected as the training cohort 33 (20%) test cohort....
Exposure to drinking water disinfection byproducts (DBPs) is potentially associated with adverse developmental effects. Iodoacetic acid (IAA), an unregulated DBP, has been shown be cytotoxic, mutagenic, genotoxic, and tumorigenic. However, its endocrine-disrupting effects remain unknown. This study evaluated the IAA-induced disruption of thyroid endocrine system using in vitro vivo assays. Rat pituitary tumor GH3 cells were treated IAA presence absence triiodothyronine (T3). exposure...
Iodoacetic acid (IAA) is the most genotoxic iodinated disinfection byproduct known in drinking water. Previous studies have shown that IAA may be an endocrine disruptor. However, whether has reproductive and developmental toxicity remains unclear. In this study, of was evaluated using a battery vitro vivo reproductive/developmental screening tests. The results E-Screen, uterotrophic, H295R steroidogenesis assays were negative. Hershberger bioassay revealed could induce significant increases...
Iodoacetic acid (IAA) is an emerging and the most genotoxic iodinated disinfection byproduct to date. IAA can disrupt thyroid endocrine function in vivo vitro, but underlying mechanisms remain unclear. In this work, transcriptome sequencing was used investigate effect of on cellular pathways human follicular epithelial cell line Nthy-ori 3-1 determine mechanism synthesis secretion hormone (TH) cells. Results indicated that affected TH pathway reduced mRNA expression stimulating receptor,...
Abstract Objective To investigate the impact of COVID-19 pandemic on life expectancy at birth ( e 0 ) for 51 Asian countries and territories from January 1, 2020 to December 31, 2021. Method Based age-sex-specific mortality used estimating changes in years 2019, 2020, 2021 2022 revision World Population Prospects, we employed Arriaga’s discrete method decompose into both absolute relative contributions age-specific death rate, further obtained contribution by country/territory period (i.e.,...
Purpose: Metastatic prostate cancer (PCa) has become a major obstacle in the treatment of PCa. The study's purpose is to find biomarkers tumor metastasis by proteomics and enzyme-linked immunosorbent assay (ELISA), design related experiments study its role progress Method: We analyzed serum from primary PCa stage metastatic 12 patients protein using isobaric tags for relative absolute quantitation (iTRAQ). An effective diagnostic model based on validated logistic regression was established....
To evaluate the capability of non-enhanced computed tomography (CT) images for distinguishing between orbital cavernous venous malformations (OCVM) and non-OCVM, to identify optimal model from radiomics-based machine learning (ML) algorithms.A total 215 cases OCVM 120 non- were retrospectively analyzed in this study. A stratified random sample 268 patients (80%) was used as training set (172 96 non-OCVM); remaining data testing set. Six feature selection techniques thirteen ML models...
The early diagnosis of colorectal cancer (CRC) is very important for the prognosis patients. It has been suggested that cytosine-phosphate-guanine (CpG) island itga4 highly methylated in adenoma cell lines AA/C1, Vaco 235 and so on. So purpose our study to explore diagnostic accuracy related mechanism integrin alpha 4 (ITGA4) CRC.The Cancer Genome Atlas (TCGA) database was used analyze relationship between expression ITGA4 clinicopathological features overall survival rate disease. Then,...
To explore the correlation between radiomic features and pathology of pure ground-glass opacities (pGGOs), we established a radiomics model for predicting pathological subtypes minimally invasive adenocarcinoma (MIA) precursor lesions.
Abstract Background To investigate the effects of computed tomography (CT) reconstruction slice thickness and contrast‐enhancement phase on differential diagnosis performance radiomic signature in lung adenocarcinoma. Methods A total 187 patients who had been pathologically confirmed with adenocarcinoma nonadenocarcinoma were divided into a training cohort ( n = 149) validation 38). All underwent contrast‐enhanced CT images reconstructed different thickness. The features extracted from scan...
Maintaining a sufficient and competent rural nursing workforce is an important goal of the Chinese health delivery system. However, few studies have investigated training status or conducted needs assessment nurses during this time great transformations in policy. This study was to explore current working township centers (THCs) ascertain their perceived needs.A cross-sectional survey using self-administered structured questionnaire among 240 THC Guangxi Zhuang Autonomous Region, China from...
To improve prognosis of cancer patients and determine the integrative value for analysis disease-free survival prediction, a clinic investigation was performed involving with 146 non-small cell lung (NSCLC) (83 men 73 women; mean age: 60.24 years ± 8.637) history surgery. Their computed tomography (CT) radiomics, clinical records, tumor immune features were firstly obtained analyzed in this study. Histology immunohistochemistry also to establish multimodal nomogram through fitting model...
It is imperative to further the understanding of drug resistance mechanisms ovarian cancer (OC) and identify useful biological markers for prognosis prediction.Cormine, cBioportal, The Cancer Genome Atlas databases were used search microarray data gene methylation related OC, in prognosis, analyze methylated genes potentially inducing OC. Fifty-five DNA-methylated significantly associated with OC screened, regulatory underlying changes levels these systematically integrated.Enrichment...
Abstract Background The overexpression of aberrant cell cycle signaling pathway associated protein has been implicated in multiple malignancies and the identification all-important one among is crux precise targeted therapy. CKAP2L (Cytoskeleton Associated Protein 2 Like) plays a newish role cancer progression through activation process mitosis. In this study, we aim to delineate prominent dysregulated expression comprehensively reveal its deregulation prostate cancer. Method was examined...
With the introduction of national policies related to sports industry, integrated development and tourism has become a new model in various locations.With transformation Guizhou Province's economic mode, ethnic emerged as prominent aspect Guizhou's brand development.It experienced rapid growth recent years made significant contributions Province.This study employs literature review, field research, interview research methods investigate mode minority resources Liupanshui City.The focuses on...
Urolithiasis is a common and recurrent condition in the urological spectrum. Despite various proposed mechanisms, causal relationship between sleep traits risk of urolithiasis remains unclear. We used publicly available genome-wide association study (GWAS) summary data from UK Biobank FinnGen to perform two-sample Mendelian randomization (MR) analysis genetic correlation analysis, evaluating (chronotype, getting up morning, duration, nap during day, insomnia) (calculus kidney ureter,...