- Radiomics and Machine Learning in Medical Imaging
- Medical Image Segmentation Techniques
- Surgical Simulation and Training
- Diet and metabolism studies
- 3D Printing in Biomedical Research
- Innovations in Medical Education
- Cancer Cells and Metastasis
- Advanced X-ray and CT Imaging
- AI in cancer detection
- Cell Image Analysis Techniques
- Biomedical and Engineering Education
- Anatomy and Medical Technology
- Electrical and Bioimpedance Tomography
Indiana University Bloomington
2023-2025
University of Colorado Denver
2025
University of Colorado Anschutz Medical Campus
2022
Abstract Functional tissue units form the basic building blocks of organs and are important for understanding modeling healthy physiological function organ changes that occur during disease states. In this comprehensive catalog 22 anatomically based, nested functional from 10 human organs, we document definition, physical dimensions, blood vasculature connections, cellular composition. All anatomy terms mapped to multi-species Uber-anatomy Ontology (Uberon) cells Cell support computational...
Abstract The Human BioMolecular Atlas Program (HuBMAP) aims to construct a 3D Reference (HRA) of the healthy adult body. Experts from 20+ consortia collaborate develop Common Coordinate Framework (CCF), knowledge graphs and tools that describe multiscale structure human body (from organs tissues down cells, genes biomarkers) use HRA characterize changes occur with aging, disease other perturbations. v.2.0 covers 4,499 unique anatomical structures, 1,195 cell types 2,089 biomarkers (such as...
Abstract More than 150 scientists from 17 consortia are collaborating on an international project to build a Human Reference Atlas, which maps all 37 trillion cells in the healthy adult human body. The initial release of this atlas provided hierarchical lists anatomical structures, cell types, and biomarkers 11 organs. Here, we describe methods used as part initiative first open, computer-readable, comprehensive database blood vasculature, called Atlas-Vasculature Common Coordinate Framework...
Abstract Efficient algorithms are needed to segment vasculature in new three-dimensional (3D) medical imaging datasets at scale for a wide range of research and clinical applications. Manual segmentation vessels images is time-consuming expensive. Computational approaches more scalable but have limitations accuracy. We organized global machine learning competition, engaging 1,401 participants, help develop deep methods 3D blood vessel segmentation. This paper presents detailed analysis the...
Mastery of embryonic heart development is challenging but critical for medical professionals due to the frequency and variety congenital cardiac defects that arise when process goes awry. Unfortunately, teaching learning embryology difficult a lack accurate effective visual resources depict this complex spatiotemporal event. To end, an interactive mobile application named Embryonic Virtual Heart Application (EVHA) was developed as accessible learner platform featuring set anatomically 3D...
Abstract Functional tissue units (FTUs) form the basic building blocks of organs and are important for understanding modeling healthy physiological function organ changes during disease states. In this first comprehensive catalog FTUs, we document definition, physical dimensions, vasculature, cellular composition 22 anatomically correct, nested functional in 10 human organs. The includes datasets, illustrations, an interactive online FTU explorer, a large printable poster. All data code...
With the transition to integrative, systems-based anatomical instruction in medical school curricula, use of traditional, regionally-based, cadaveric dissection has decreased while prosections increased. Recent studies have demonstrated value such for nervous system through an en bloc extraction central system. However, comparable approaches circulatory not been reported, and there are currently no instructions that do require polymer injection into vessels prior embalming. Thus, goal this...