A5017534587- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Zoonotic diseases and public health
- Animal Disease Management and Epidemiology
- Microbial infections and disease research
- Toxoplasma gondii Research Studies
- Parasitic Infections and Diagnostics
- Herpesvirus Infections and Treatments
- Viral Infections and Vectors
- Parasitic infections in humans and animals
- Yersinia bacterium, plague, ectoparasites research
- Congenital Anomalies and Fetal Surgery
- Parasite Biology and Host Interactions
- Diagnosis and treatment of tuberculosis
- Mosquito-borne diseases and control
- Brucella: diagnosis, epidemiology, treatment
- Leptospirosis research and findings
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 and COVID-19 Research
- Vector-borne infectious diseases
- Wildlife Ecology and Conservation
- Parasitic Diseases Research and Treatment
- Rabies epidemiology and control
- Infectious Diseases and Tuberculosis
- Vector-Borne Animal Diseases
Laboratoire de Recherches sur le Développement de l'Elevage
2008-2024
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2015-2024
Office National de la Chasse et de la Faune Sauvage
2010-2024
Modèles Insectes de l'Immunité Innée
2020-2023
Centre hospitalier régional d'Orléans
2019
Centre de Recherche en Nutrition Humaine d'Auvergne
2009-2010
Département Santé Animale
2010
Département Génétique Animale
2010
École Nationale Vétérinaire d'Alfort
2005
Wildlife species as reservoirs of infectious pathogens represent a serious constraint in the implementation disease management strategies. In Mediterranean island Corsica, dynamics hepatitis E virus (HEV) and Aujeszky's (ADV) are suspected to be influenced by interactions between wild domestic pigs. To improve our understanding these influences, we first compared seroprevalences both viruses pig populations from different locations with contrasted levels wild-domestic interactions, ADV...
Understanding the pathogenesis of SARS-CoV-2 infection is key to developing preventive and therapeutic strategies against COVID-19, in case severe illness but also when disease mild. The use appropriate experimental animal models remains central vivo exploration physiopathology antiviral strategies. This study describes intranasal ferrets hamsters with low doses low-passage clinical French isolate UCN19, describing levels, excretion, immune responses pathological patterns both species....
Mycobacterium bovis infection was first described in free-ranging wildlife France 2001, with subsequent detection hunter-harvested ungulates and badgers areas where outbreaks of bovine tuberculosis (TB) were also detected cattle. Increasing concerns regarding TB led the French General Directorate for Food (DGAL) main institutions involved animal health management, to establish a national surveillance system wildlife. This is known as 'Sylvatub'. The coordinates activities various local...
SUMMARY The risk for a pathogen to cross the species barrier depends on rate of efficient contacts between species. However, contact rates have rarely been estimated from observations. Here we estimate and exposure chamois Rupicapra rupicapra Alpine ibex Capra exposed domestic pasteurellosis brucellosis carried by sheep or cattle herds summering in mountain pastures. We use field observation data animal positions treated geographic information system (GIS). Comparing 10 pastures, show that...
The purpose of this study was to develop a standardized tool for the assessment surveillance systems on zoonoses and animal diseases. We reviewed three existing methods combined them semi-quantitative associating their strengths providing way display multilevel results. developed set 78 criteria divided into ten sections, representing functional parts system. Each criterion given score according prescription scoring guide. Three graphical outputs were generated using specific combination...
Animal tuberculosis (TB) is a multi-host zoonotic disease whose prevalence in cattle herds Europe has been increasing, despite huge investment eradication. The composition of the host community fundamental driver pathogen transmission, and yet this not formally quantified for animal TB Europe. We communities TB, using stochastic models to estimate number infected domestic wild hosts three regions: officially TB-free Central–Western Europe, two largely TB-endemic regions, Iberian Peninsula...
The Eurasian wild boar (Sus scrofa) is increasingly considered as a relevant actor in the epidemiology of animal tuberculosis (TB). Therefore, monitoring TB becomes key tool for establishing comprehensive control schemes this disease. To estimate exposure free living to Mycobacterium complex (MTC) France, bovine-purified protein derivative based ELISA was used test 2,080 archived serum samples hunter-harvested animals 58 French "départements". Two cut-off values were diagnostic...
SUMMARY Knowledge of the factors affecting presence Toxoplasma gondii in wildlife is limited. Here we analyse which local landscape characteristics are associated with toxoplasmosis wild boar, Sus scrofa , on island Corsica, France. Meat juice samples from 1399 boars collected during two hunting seasons were tested for T. antibodies using modified agglutination test (titre 1:4). The overall seroprevalence was 0·55 (95% CI 0·50–0·59) first year and 0·33 0·29–0·35) second year. Seroprevalence...
The zoonotic agent of bovine tuberculosis (bTB), Mycobacterium bovis, can be transmitted between domestic and wild animals, threatening wildlife populations control programs for bTB in cattle. In Corsica, a French Mediterranean island where species have close interactions, cases been reported cattle, pigs, boar. Moreover, genotypes M. bovis found animals from the same area were identical. These data strongly suggest that are associated an epidemiologic bTB-transmission cycle. More...
Human cystic echinococcosis (hydatid disease) caused by the Echinococcus granulosus tapeworm continues to be a substantial cause of morbidity and mortality in many parts world. France is still considered as endemic area, but current infestation E. intermediate hosts remains currently unknown due absence official data reporting for last 20 years. A 1-year prevalence survey was conducted 24 slaughterhouses ten departments South France. We demonstrate that parasite present at low study area (4...
In September 2016, a cluster of seven kayakers with clinical symptoms leptospirosis onset since July 2016 was reported to French health authorities. Human and animal investigations were undertaken describe the outbreak, identify likely place source infection implement necessary control measures. We identified 103 patients between 1 June 31 October who lived in Ille-et-Vilaine district Brittany. Of these, 14 (including original seven) contacts river Vilaine during incubation period defined as...
In recent years, outbreaks caused by multi-host pathogens (MHP) have posed a serious challenge to public and animal health authorities. The frequent implication of wildlife in such disease systems lack guidelines for mitigating these diseases within wild populations partially explain why the are particularly challenging. To face challenges, French Ministry Agriculture launched multi-disciplinary group experts that set out discuss main specific concepts management MHP how integrate...
In France, animal tuberculosis (TB) due to Mycobacterium bovis (M. bovis) affects a multi-host community that include cattle and wildlife species such as wild boars (Sus scrofa), badgers (Meles meles), or deer (Cervus elaphus, Capreolus capreolus). The involvement of foxes in the epidemiology TB is fairly described countries facing multispecies concerns. After discovery grouped cases French endemic region, study was implemented core four areas Dordogne, Charente, Landes (departments...
A greater knowledge of the ecology natural foci tick-borne encephalitis virus (TBEV) is essential to better assess temporal variations risk for humans. To describe seasonal and inter-annual TBEV-cycle epidemiological parameters related TBEV nymph-to-larva transmission, exposure small mammals TBEV, tick aggregation on mammals, a longitudinal survey in ticks was conducted over 3-year period mountain forest Alsace, eastern France. prevalence questing nymphs lower 2013 than 2012 2014, probably...
Although control measures to tackle bovine tuberculosis (bTB) in cattle have been successful many parts of Europe, this disease has not eradicated areas where Mycobacterium bovis circulates multi-host systems. Here we analyzed the resurgence 11 M. genotypes (defined based on spoligotyping and MIRU-VNTR) detected 141 farms between 2007 2019, an area Southwestern France wildlife infection was also from 2012 65 badgers. We used a spatially-explicit model reconstruct simultaneous diffusion...