A5041930273- Wheat and Barley Genetics and Pathology
- Thyroid Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Antimicrobial Resistance in Staphylococcus
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Streptococcal Infections and Treatments
- RNA modifications and cancer
- Pneumonia and Respiratory Infections
- Peroxisome Proliferator-Activated Receptors
- Multiple Myeloma Research and Treatments
- Cancer, Lipids, and Metabolism
- Thyroid and Parathyroid Surgery
- Circular RNAs in diseases
- Plant Disease Resistance and Genetics
- Bacterial Infections and Vaccines
- Head and Neck Anomalies
- Ubiquitin and proteasome pathways
- Cancer Immunotherapy and Biomarkers
- Fibroblast Growth Factor Research
- Salivary Gland Disorders and Functions
- Head and Neck Surgical Oncology
- RNA Research and Splicing
- Celiac Disease Research and Management
- Bacterial Identification and Susceptibility Testing
Capital Medical University
2012-2025
Beijing Tongren Hospital
2017-2025
Ministry of Education of the People's Republic of China
2020-2025
University of Electronic Science and Technology of China
2024
Guangxi University of Chinese Medicine
2024
Nanjing Medical University
2023-2024
Jiangsu Province Hospital
2023-2024
National Institute for Viral Disease Control and Prevention
2023
Beijing Institute of Neurosurgery
2023
Hebei Medical University
2022
A wheat cultivar “Chinese Spring” chromosome substitution line CS-1Sl(1B), in which the 1B was substituted by 1Sl from Aegilops longissima, developed and found to possess superior dough breadmaking quality. The molecular mechanism of its super quality conformation is studied aspects high glutenin genes, protein accumulation patterns, polymeric proteins, bodies, starch granules, disulfide isomerase (PDI) PDI-like expressions. Results showed that introduced HMW-GS 1Sl×2.3* 1Sly16* possesses...
It has been demonstrated that PPARG may interact with the PTEN-PI3K/AKT pathway, contributing to its involvement in chemotherapy treatment of hypopharyngeal squamous cell carcinoma (HSCC). However, underlying mechanism remains largely unknown. In this study, gene expression profiles 17 HSCC patients, comprising 8 chemotherapy-sensitive patients (CSP) and 9 chemotherapy-nonsensitive (CNSP), were collected analyzed investigate patterns, correlations, influencing factors PPARG-PTEN-PI3K/AKT...
Low-molecular-weight glutenin subunits (LMW-GS), encoded by Glu-3 complex loci in hexaploid wheat, play important roles the processing quality of wheat flour. To date, molecular characteristics and effects on dough individual alleles their encoding proteins have been poorly studied. We used a Glu-A3 deletion line Chinese Spring (CS-n) variety to conduct first comprehensive study functional properties LMW-GS allele Glu-A3a.The Glu-A3a at locus CS its CS-n were identified characterized...
Exosomes are small vesicles with a diameter of 30~150 nm secreted by cells, which rich in mRNA, microRNA, and long noncoding RNA (lncRNA). The biological functions most exosomal lncRNAs not well understood. Studies have shown that tumor exosome FGD5-AS1 plays an important role the proliferation, migration, invasion cells. In this study, SW1736 KAT18 TC cells high expression were screened. collected. collected exosomes then added to HUVEC After incubation for 24 h, effects on proliferation...
SUMMARY The characteristics of 359 group A streptococcal (GAS) isolates collected from Chinese paediatric patients in two periods (1993–1994, 2005–2006) were studied. Isolates assigned to emm types and assayed for eight superantigen (SAg) genes ( speA , speC speH speI speG speJ ssa SMEZ ). Types 1 12 consistently the most prevalent during periods, while others varied frequency. GAS carrying six or more SAg increased 46·53% (1993–1994) 78·39% (2005–2006); P <0·05) but declined <0·05)....
A wheat cultivar ''Chinese Spring'' chromosome substitution line CS-1S l (1B), in which the 1B was substituted by 1S from Aegilops longissima, developed and found to possess superior dough breadmaking quality.The molecular mechanism of its super quality conformation is studied aspects high glutenin genes, protein accumulation patterns, polymeric proteins, bodies, starch granules, disulfide isomerase (PDI) PDI-like expressions.Results showed that introduced HMW-GS 62.3* y16* possesses long...
Colorectal carcinoma is currently the third most frequent cancer worldwide. Conventional open surgery was replaced by laparoscopic anterior resection with total mesorectal excision for treatment of sigmoid and rectal carcinomas; however, it needed an incision to harvest specimen, which contributed complications. In 2013, trans-anal natural orifice specimen extraction (Ta-NOSE-LAR) treat performed in our hospital first time. The aim this study investigate outcomes Ta-NOSE-LAR carcinoma....
This prospective, multicentre, nasal carriage study in Chinese children with upper respiratory infection was carried out over the period from 2000 to 2002. Overall, prevalence of pneumococcal 24.9%. Antimicrobial susceptibility tests were performed for 887 isolates Streptococcus pneumoniae which 33.5% intermediately susceptible penicillin and 6.4% resistant. Multidrug resistance very common. Pneumococcal strains ( n = 625) serotyped, showing 72.2% covered by 23-valent polysaccharide vaccine...
Abstract Aim: To investigate the characteristic of community‐associated methicillin‐resistant staphylococcus aureus (CA‐MRSA) skin and soft tissue infections (SSTIs) among children in China. Methods: Forty‐seven with CA‐MRSA SSTIs were enrolled this study. Clinical information was collected analysed. The strains from analysed by multilocus sequence typing (MLST), cassette chromosome mec (SCCmec) spa typing. Panton‐Valentine leukocidin (PVL) gene also detected. Results: majority 47 cases...
To investigate the prognosis and related factors impacting renal response in newly diagnosed multiple myeloma (NDMM) patients with impairment.
Abstract Long non‐coding RNA DLX6 antisense 1 (DLX6‐AS1) lists a critical position in thyroid carcinoma (TC) development. However, the overall comprehension about DLX6‐AS1, microRNA (miR)‐193b‐3p and homeobox A1 (HOXA1) TC is not thoroughly enough. Concerning to this, this work pivoted on DLX6‐AS1/miR‐193b‐3p/HOXA1 axis cell growth autophagy. tissues adjacent normal were collected, which expression of miR‐193b‐3p HOXA1 was tested, together with their interactions. cells transfected...
To investigate the pattern of antibiotic use in pulmonology wards four children's hospitals China from 2002 to 2006.The Anatomical Therapeutic Chemical Classification/Defined Daily Doses (ATC/DDD) methodology was used. Aggregate data on (ATC code-J01) were expressed numbers DDD/100 bed-days for inpatients.The overall consumption drugs 83.7, 49.9, 53.6 and 79.3 bed-days, respectively. Injectables among most widely used antibiotics. In addition, there a considerable variation both amount...
The upregulation of peroxisome proliferator-activated receptor gamma (PPARG) has been shown to increase the chemosensitivity several human cancers. This study is aimed at studying if PPARG sensitizes hypopharyngeal squamous cell carcinoma (HSCC) in chemotherapeutic treatments and dissecting possible mechanisms observed effects. We integrated large-scale literature data HSCC gene expression identify regulatory pathways that link HSCC. Expression levels molecules within were compared 21...
Abstract Background We performed a paired analysis to compare the therapeutic effect between induction chemotherapy‐based organ‐preservation approach and immediate total laryngectomy in hypopharyngeal squamous cell carcinoma patients requiring laryngectomy. Methods 351 who were treated with compared 110 The main measures outcomes progression‐free survival (PFS), overall (OS), larynx function preservation (LFPS). Results No statistical difference was observed for 3‐, 5‐, 10‐year PFS OS two...