Xiaojie Fang

ORCID: 0000-0002-5874-9845
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About
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Research Areas
  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Lymphoma Diagnosis and Treatment
  • Cancer Research and Treatments
  • T-cell and Retrovirus Studies
  • Colorectal and Anal Carcinomas
  • Cancer, Hypoxia, and Metabolism
  • Protein Degradation and Inhibitors
  • MicroRNA in disease regulation
  • Cancer Treatment and Pharmacology
  • Immune Cell Function and Interaction
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer-related gene regulation
  • Histone Deacetylase Inhibitors Research
  • Cancer therapeutics and mechanisms
  • Cancer-related molecular mechanisms research
  • Acute Lymphoblastic Leukemia research
  • Probiotics and Fermented Foods
  • RNA modifications and cancer
  • Diet and metabolism studies
  • Viral-associated cancers and disorders

Sun Yat-sen University
2016-2025

Sun Yat-sen University Cancer Center
2016-2025

The First People’s Hospital of Lianyungang
2023

Guangdong Provincial Hospital of Traditional Chinese Medicine
2021

Numerous studies have demonstrated that aberrant microRNA (miRNA) expression is involved in human disease including cancer. To date, the potential miRNAs regulating lung cancer growth and progression are not fully identified yet.In this study, of miR-142-5p was measured non-small cell tissue lines by qRT-PCR. The functional assays viability, colony formation, migration invasion were performed mimic or inhibitor transfected (in vitro) tumorigenesis nude mice vivo). fluorescence ratios...

10.1159/000484459 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2017-01-01

To investigate the value of pretreatment nasopharyngeal and neck magnetic resonance imaging (NN-MRI) combined with positron emission tomography (PET)/CT-guided therapy for improving survival in upper aerodigestive tract NK/T-cell lymphoma (UADT-NKTL) patients. We performed a prospective cohort study including 171 untreated patients histologically diagnosed UADT-NKTL, whom 71 received PET/CT NN-MRI other 100 alone. The clinical stage every patient was classified according to Ann Arbor TNM...

10.1002/hed.28137 article EN Head & Neck 2025-04-03

Aims To reveal the consistency and discrepancy in gut microbial structure function inflammatory bowel disease (IBD) patients from different regions. Methods Results Gut microbes, antibiotic resistance genes (ARGs) virulence factors (VFGs) were analysed using metagenome data three cohorts. The abundance of Escherichia coli extensively increased IBD patients, whereas Subdoligranulum unclassified decreased dramatically countries. showed a positive correlation with multiple ARGs VFGs cohorts...

10.1111/jam.15154 article EN Journal of Applied Microbiology 2021-05-19

3094 Background: TQB3617 is a first-in-class, oral, small molecular inhibitor of the bromodomain and extra terminal (BET) protein family. This an open-label, Phase I study investigated monotherapy to treat advanced malignant tumors (NCT05110807). Here, we report primary results in patients with (pts/w) hematologic malignancies. Methods: modified 3 + design dose escalation study. Aged ≥18 years old, ECOG PS score 0~2, pts/w malignancy tumor who had failed standard treatment or were unable...

10.1200/jco.2024.42.16_suppl.3094 article EN Journal of Clinical Oncology 2024-06-01

// Xueying Li 1, * , Xiaojie Fang Su 2 Weijing Zhang 3 Nong Yang 4 Yimin Cui 5 He Huang 1 Ruiqing Cai Xiaoting Lin Xiaohong Fu Huangming Hong Tongyu Department of Medical Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory Oncology in Southern China, Collaborative Innovation Center Medicine, Guangzhou, China Clinical Trials Research Lymphoma, The 307th Hospital Chinese People's Liberation Army, Beijing, Hunan Hospital, Changsha, Pharmacy, Peking First These authors...

10.18632/oncotarget.7875 article EN Oncotarget 2016-03-03
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