A5082494281- Salmonella and Campylobacter epidemiology
- Brucella: diagnosis, epidemiology, treatment
- Antibiotic Resistance in Bacteria
- Bacteriophages and microbial interactions
- Escherichia coli research studies
- Galectins and Cancer Biology
- Monoclonal and Polyclonal Antibodies Research
- Burkholderia infections and melioidosis
- Vibrio bacteria research studies
- Cancer Research and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial Genetics and Biotechnology
- Enterobacteriaceae and Cronobacter Research
- Drug Transport and Resistance Mechanisms
- Glycosylation and Glycoproteins Research
- Genomics and Phylogenetic Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- RNA and protein synthesis mechanisms
- Probiotics and Fermented Foods
- Animal Diversity and Health Studies
- Mycobacterium research and diagnosis
- Antibiotic Use and Resistance
- Cancer therapeutics and mechanisms
- Bacterial biofilms and quorum sensing
- Plant Pathogenic Bacteria Studies
Université de Tours
2013-2025
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2025
Infectiologie Animale et Santé Publique
2015-2024
Institut National de la Recherche Agronomique
2007-2019
Institut National de la Recherche Agronomique du Niger
2006-2013
Physiologie de la Reproduction et des Comportements
2013
Biologie des Oiseaux et Aviculture
1996-2005
Chang Gung Children's Hospital
2005
Centro de Investigación y Tecnología Agroalimentaria de Aragón
2003
Centre d'Immunologie et des Maladies Infectieuses
2003
Small Gram-negative cocco-bacilli resembling Brucella strains have been reported from marine mammals since the mid-1990s. Their placement in genus has supported by following characteristics: they are aerobic, non-motile and catalase-positive, do not produce acid carbohydrates a DNA–DNA relatedness value of >77 % with six established members genus. Twenty-eight European isolates were distinguished recognized species their pattern utilization eleven substrates oxidative metabolism tests...
This study describes the characterization of recently described Salmonella genomic island 1 (SGI1) (D. A. Boyd, G. Peters, L.-K. Ng, and M. R. Mulvey, FEMS Microbiol. Lett. 189:285-291, 2000), which harbors genes associated with ACSSuT phenotype in a Canadian isolate enterica serovar Typhimurium DT104. A 43-kb region has been completely sequenced found to contain 44 predicted open reading frames (ORFs) comprised approximately 87% total sequence. Fifteen ORFs did not show any significant...
Two Gram-negative, non-motile, non-spore-forming, coccoid bacteria (strains CCM 4915T and 4916), isolated from clinical specimens of the common vole Microtus arvalis during an epizootic in Czech Republic 2001, were subjected to a polyphasic taxonomic study. On basis 16S rRNA (rrs) recA gene sequence similarities, both isolates allocated genus Brucella. Affiliation Brucella was confirmed by DNA–DNA hybridization studies. Both strains reacted equally with M-monospecific antiserum lysed...
A Gram-negative, non-motile, non-spore-forming coccoid bacterium (strain BO1(T)) was isolated recently from a breast implant infection of 71-year-old female patient with clinical signs brucellosis. Affiliation strain BO1(T) to the genus Brucella confirmed by means polyamine pattern, polar lipid profile, fatty acid quinone system, DNA-DNA hybridization studies and insertion sequence 711 (IS711)-specific PCR. Strain harboured four five copies Brucella-specific element IS 711, displaying unique...
National Salmonella surveillance systems from France, England and Wales, Denmark, the United States identified recent emergence of multidrug-resistant isolates enterica serotype Kentucky displaying high-level resistance to ciprofloxacin. A total 489 human cases were during period 2002 (3 cases) 2008 (174 cases). These belonged a single clone defined by multilocus sequence type ST198, XbaI-pulsed-field gel electrophoresis cluster X1, presence genomic island 1 variant SGI1-K. This was probably...
Two Gram-negative, non-motile, non-spore-forming coccoid bacteria (strains F8/08-60 T and F8/08-61) isolated from clinical specimens obtained baboons ( Papio spp.) that had delivered stillborn offspring were subjected to a polyphasic taxonomic study. On the basis of 16S rRNA gene sequence similarities, both strains, which possessed identical sequences, assigned genus Brucella . This placement was confirmed by extended multilocus analysis (MLSA), where strains whole-genome sequencing...
Two slow-growing, Gram-negative, non-motile, non-spore-forming, coccoid bacteria (strains F60T and F965), isolated in Austria from mandibular lymph nodes of two red foxes (Vulpes vulpes), were subjected to a polyphasic taxonomic analysis. In recent study, both isolates assigned the genus Brucella but could not be attributed any existing species. Hence, we have analysed strains further detail determine their exact position genetic relatedness other members Brucella. The genome sizes F965 3...
An evaluation of a multiplex PCR assay (Bruce-ladder) was performed in seven laboratories using 625 Brucella strains from different animal and geographical origins. This robust test can differentiate single step all the classical species, including those found marine mammals S19, RB51, Rev.1 vaccine strains.
Salmonella genomic island 1 (SGI1) is a containing an antibiotic resistance gene cluster identified in several enterica serovars. The SGI1 cluster, which complex class integron, confers the common multidrug phenotype of epidemic S. Typhimurium DT104. occurrence serovars Typhimurium, Agona, Paratyphi B, Albany, Meleagridis and Newport indicates horizontal transfer potential SGI1. Here, we report that could be conjugally transferred from donor strains to non-SGI1 Escherichia coli recipient...
ABSTRACT The occurrence of active efflux and cell wall modifications were studied in Salmonella enterica serovar Typhimurium mutants that selected with enrofloxacin whose phenotypes resistance to fluoroquinolones could not be explained only by mutations the genes coding for gyrase or topoisomerase IV. Mutant BN18/21 exhibited a decreased susceptibility ciprofloxacin (MIC = 0.125 μg/ml) but did have mutation gyrA gene. Mutants BN18/41 BN18/71 had same substitution, Gly81Cys GyrA, different...
ABSTRACT Strains of multidrug-resistant Salmonella enterica serovar Typhimurium DT104 (DT104) and S. Agona (Agona) have been found to harbor genomic island 1 (SGI1), a 43-kb region that contains many the drug resistance genes. Such strains are resistant ampicillin ( pse-1 ), chloramphenicol/florfenicol floR streptomycin/spectinomycin aadA2 sulfonamides sul1 tetracycline [ tet (G)] (commonly called ACSSuT phenotype). All five genes in 13-kb multidrug (MDR) consisting an unusual class I...
Salmonella enterica serovar Typhimurium phage type DT204 strains isolated from cattle and animal feed in Belgium were characterized for high-level fluoroquinolone resistance mechanisms [MICs to enrofloxacin (Enr) ciprofloxacin (Cip), 64 32 μg/ml, respectively]. These during the periods 1991-1994, 2000 clonally related as shown by pulsed-field gel electrophoresis (PFGE). Selected studied carried several mutations quinolone target genes, i.e., a double mutation resistance-determining region...
In the sequenced genome of Salmonella enterica serovar Typhimurium strain LT2, an open reading frame (STM0580) coding for a putative regulatory protein TetR family is found upstream ramA gene. Overexpression results in increased expression AcrAB efflux pump and, consequently, multidrug resistance (MDR) several bacterial species. The inactivation gene susceptible resulted MDR phenotype with fourfold increases MICs unrelated antibiotics, such as quinolones/fluoroquinolones, phenicols, and...
While the spread of Salmonella enterica serotype Kentucky resistant to ciprofloxacin across Africa and Middle-East has been described recently, presence this strain in humans, food, various animal species (livestock, pets, wildlife) environment is suspected other countries different continents. Here, we report results an in-depth molecular epidemiological study on a global human non-human collection S. (n = 70). We performed XbaI-pulsed field gel electrophoresis multilocus sequence typing,...
Multidrug-resistant Salmonella enterica serovar Typhimurium definitive phage type 104 (DT104) strains harbor a genomic island, called island 1 (SGI1), which contains an antibiotic resistance gene cluster conferring to ampicillin, chloramphenicol, florfenicol, streptomycin, sulfonamides, and tetracyclines. They may be additionally resistant quinolones. Among the genes there are two, i.e., floR tet(G), code for efflux pumps of major facilitator superfamily with 12 transmembrane segments that...