A5022943650- Climate variability and models
- Meteorological Phenomena and Simulations
- Oceanographic and Atmospheric Processes
- Tropical and Extratropical Cyclones Research
- Energy Load and Power Forecasting
- Cancer, Hypoxia, and Metabolism
- Arctic and Antarctic ice dynamics
- Cancer Cells and Metastasis
- Impact of Technology on Adolescents
- Atmospheric and Environmental Gas Dynamics
- Plant Water Relations and Carbon Dynamics
- Salivary Gland Tumors Diagnosis and Treatment
- RNA modifications and cancer
- Remote Sensing and Land Use
- Photodynamic Therapy Research Studies
- Perfectionism, Procrastination, Anxiety Studies
- MicroRNA in disease regulation
- Autoimmune Neurological Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Hydrological Forecasting Using AI
- Visual and Cognitive Learning Processes
- Technology Adoption and User Behaviour
- Cardiovascular Disease and Adiposity
- Spatial Cognition and Navigation
- Cancer-related molecular mechanisms research
Hanyang University
2012-2025
Yonsei University
2013-2024
Severance Hospital
2023
Pusan National University
2011-2022
Computational Physics (United States)
2019-2020
Los Alamos National Laboratory
2019-2020
Yonsei University College of Dentistry
2013-2019
Barcelona Supercomputing Center
2016-2019
Universitat Politècnica de Catalunya
2016-2019
Seoul National University Hospital
2015-2018
Objective To evaluate the seizure characteristics and outcome after immunotherapy in adult patients with autoimmune encephalitis (AE) new-onset seizure. Methods Adult (age ≥18 years) AE who underwent were followed-up for at least 6 months included. Seizure frequency was evaluated 2–4 weeks onset of initial categorized as “seizure remission”, “> 50% reduction”, or “no change” based on degree its decrease. Results Forty-one presented analysed. At immunotherapy, 51.2% free, 24.4% had...
Crosstalk between cancer cells and carcinoma-associated fibroblasts (CAFs) has earned recognition as an interaction that plays a pivotal role in carcinogenesis. Thus, we attempted to clarify whether increase the level of CAFs promotes progression by proportionally enhancing CAFs. We first analyzed clinical correlation levels found made noticeable difference on prognosis patients with oral squamous cell carcinoma (OSCC). In vivo animal study also demonstrated tumor volume depended dose was...
With the recent advancement in transcriptome-wide profiling approach, numerous non-coding transcripts previously unknown have been identified. Among transcripts, long RNAs (lncRNAs) received increasing attention for
Abstract The complex interaction between the Pacific Decadal Oscillation (PDO) and East Asian winter temperatures remains unclear. This study reveals that since early 2000s, Asia has experienced a strengthening of Aleutian Low Siberian High during negative PDO phases, leading to an intensified monsoon (EAWM). increased pressure gradient Low, driven by warming in western associated with phase, significantly contributed shift toward cooling (105°–150° E, 20°–50° N) 2000s. Observations model...
Molecular crosstalk between cancer cells and fibroblasts has been an emerging hot issue in understanding carcinogenesis. As oral submucous fibrosis (OSF) is inflammatory fibrotic disease that can potentially transform into squamous cell carcinoma, OSF considered to be appropriate model for studying the role of during early stage In this sense, study aims at investigating whether areca nut (AN)-exposed cause DNA damage epithelial cells. For study, immortalized hNOF (hTERT-hNOF) was used. We...
The present study applied the technology acceptance model to examine determinants leading learners' behavioral intention use a multimedia-based learning system. Four exogenous constructs—multimedia self-efficacy, perceived richness of multimedia presentation, learner control, and system responsiveness—were externally added framework improve its predictive power for specific context. In addition, second-order construct cognitive engagement was created based upon dimensions curiosity,...
Abstract Climate variability and change in the Southern Hemisphere (SH) are influenced by Annular Mode (SAM) closely related to changes kinematic properties of SH surface zonal winds. The SAM winds have strong effects on atmospheric oceanic circulation system. In this study we investigate trend position strength wind stress (TAUX), using two ensembles simulations covering historical record from Energy Exascale Earth System Model (E3SM‐HIST Atmospheric Intercomparison Project) for 1979–2014....
Abstract Aims . To evaluate the efficacy and safety of mega‐dose phenobarbital (MDPB; enteral or parenteral >10 mg/kg/day) for treating super‐refractory status epilepticus (SRSE; continuous recurrent ≥24 hours after onset anaesthetic treatment) in adult patients. Methods Adult patients with SRSE who were treated MDPB our institution from March 2005 to September 2014 reviewed. We collected data on basic demographics, clinical features, functional status, anticonvulsant treatment, possible...
[1] Using the APEC Climate Center (APCC) operational multimodel ensemble (MME) hindcasts of precipitation and temperature at 850 hPa for boreal winters period 1981–2003, along with those individual models as well corresponding observed reanalyzed data, we propose use a “climate” filter to diagnose improve prediction skills. The “filter” is based on strong association between El Niño–Southern Oscillation (ENSO)-associated Walker circulation tropical Pacific rainfall. reproducibility this...
Abstract Objective Maternal immune activation (MIA) is associated with an increased risk of autism spectrum disorder (ASD) in offspring. Herein, we investigate the altered expression microRNAs (miRNA), and that their target genes, brains MIA mouse Methods To generate model mice, pregnant mice were injected polyriboinosinic:polyribocytidylic acid on embryonic day 12.5. We performed miRNA microarray mRNA sequencing order to determine differential between controls, at 3 weeks age. further...
The characteristics and predictability of climate anomalies over the tropical Indian Ocean (TIO) South Asian region during boreal summer (June-July-August) 2010 are investigated on basis atmospheric regional model simulations five forecasts obtained from Asia-Pacific Economic Cooperation Climate Center coupled models. robust features basin-wide TIO warming enhanced (suppressed) rainfall north maritime continent (head Bay Bengal parts monsoon trough region). Our experiments corroborate that...
ABSTRACT The current status and future changes in the frequency intensity of climatological blocking activity over North Pacific region are investigated using historical two Representative Concentration Pathway ( RCP4.5 8.5) simulations coupled climate models from phase 5 Coupled Model Intercomparison Project CMIP5 ) for boreal winters (December–February) a 30‐year period. change examined terms projected meridional thickness gradient, Hadley circulation changes, probability distribution...
The prediction skills of climate model simulations in the western tropical Pacific (WTP) and East Asian region are assessed using retrospective forecasts seven state-of-the-art coupled models their multi-model ensemble (MME) for boreal summers (June–August) during period 1983–2005, along with corresponding observed reanalyzed data. summer rainfall anomalies Asia is difficult, while WTP has a strong correlation between observation. We focus on developing new approach to further enhance...
Abstract The authors propose the use of a “climate filter” concept to enhance prediction skill multimodel ensemble (MME) suite for East Asian summer monsoon (EASM) precipitation and temperature at 850 hPa. method envisages grading models on basis degree reproducibility association EASM variability with few relevant climate drivers respective model hindcasts period 1981–2003. analysis identifies previous winter Niño-3.4 spring North Atlantic Oscillation indices as most suitable in designing...