Sarah A. Holzman

ORCID: 0000-0002-6308-9917
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About
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Research Areas
  • Urological Disorders and Treatments
  • Renal cell carcinoma treatment
  • Urologic and reproductive health conditions
  • Pediatric Urology and Nephrology Studies
  • Renal and related cancers
  • Ferroptosis and cancer prognosis
  • Urinary Tract Infections Management
  • Cancer Immunotherapy and Biomarkers
  • Hernia repair and management
  • Testicular diseases and treatments
  • Sexual Differentiation and Disorders
  • Periodontal Regeneration and Treatments
  • COVID-19 and healthcare impacts
  • Tissue Engineering and Regenerative Medicine
  • Bladder and Urothelial Cancer Treatments
  • Prostate Cancer Diagnosis and Treatment
  • Patient Satisfaction in Healthcare
  • Facial Trauma and Fracture Management
  • Eosinophilic Disorders and Syndromes
  • Reconstructive Surgery and Microvascular Techniques
  • Genital Health and Disease
  • Immunotherapy and Immune Responses
  • Peptidase Inhibition and Analysis
  • Trauma Management and Diagnosis
  • Cleft Lip and Palate Research

University of California, Irvine
2020-2023

Children's Hospital of Orange County
2020-2023

MedStar Georgetown University Hospital
2020

Georgetown University
2017

Emory University
2014-2016

University of Arkansas Medical Center
1994

Inserm
1983

Université Paris Cité
1983

Prenatal hydronephrosis is one of the most common anomalies detected on prenatal ultrasonography. Patients with and ureteral dilation are at increased risk urinary tract infection (UTI) continuous antibiotic prophylaxis (CAP) recommended. However, current guidelines do not define minimum diameter that would be considered a dilated ureter in these patients.We evaluate definition clinically relevant hydroureter, its association UTI, impact CAP.Patients from seven centers were enrolled into...

10.1016/j.jpurol.2021.09.001 article EN cc-by-nc-nd Journal of Pediatric Urology 2021-09-08

BackgroundAlthough hypospadias outcomes studies typically report a level or type of repair performed, these often lack applicability to each surgical practice due technical variability that is not fully delineated. An example the tubularized incised plate (TIP) urethroplasty procedure, for which modifications have been associated with significantly decreased complication rates in single center series. However, many fail specificity techniques utilized, thereby limiting comparison between...

10.1016/j.jpurol.2022.12.001 article EN cc-by-nc-nd Journal of Pediatric Urology 2023-01-11

Telemedicine has increased during the coronavirus disease 2019 pandemic. Our objective was to determine if patient satisfaction with telemedicine differed from in-person visits in an academic pediatric urology clinic. Following outpatient and visits, validated NRC Health© Patient Survey used assess experience. assessed on a 10-point scale scores of 9–10 considered “satisfied” 1–8 “not satisfied.” Satisfaction between groups were compared using McNemar’s test, Wilcoxon signed rank conditional...

10.1177/13674935211058272 article EN other-oa Journal of Child Health Care 2021-12-06

Hyaluronic acid (HA) solution has the ability to coat and lubricate serosal surfaces, potentially prevent trauma during surgery, which can result in postoperative formation of adhesions abdomen. Previous animal studies utilizing HA have shown a reduction intra-abdominal adhesion formation. Human clinical trials are currently underway. The prevention could conceivably deleterious effects on bowel anastomosis healing. As result, solutions were studied rabbits determine their effect healing...

10.3109/08941939409016509 article EN Journal of Investigative Surgery 1994-01-01

The use of autologous tissue grafts for tunica albuginea repair in Peyronie's disease and congenital chordee is often restricted by limited availability donor site morbidity, therefore new biomaterial options are needed. In this study, bi-layer silk fibroin (BLSF) scaffolds were investigated to support functional regeneration a rabbit corporoplasty model. Eighteen adult male, New Zealand white rabbits randomized nonsurgical controls (NSC, N = 3), or subjected with BLSF (N 5); decellularized...

10.3389/fbioe.2021.791119 article EN cc-by Frontiers in Bioengineering and Biotechnology 2021-12-07

To examine the prognostic value of tumor major histocompatibility complex I (MHCI) expression on survival and recurrence in patients with clear cell renal carcinoma (RCC). Fifty-three that underwent nephrectomy at our institution for RCC (T1-T3) ≥4 years follow-up were queried from database. Immunohistochemical staining MHCI was performed specimens quantified an automated image analysis technique. Patients divided into high low groups order to study relationship between prognosis using...

10.1016/j.ajur.2016.02.001 article EN cc-by-nc-nd Asian journal of urology 2016-02-26

F ree gingival autografts still remain the most predictable method for creating attached gingiva. However, a need exists sources of connective tissue other than patient's own tissue. Yukna et al. have proposed freeze‐dried skin (FDS) allografts as substitute autografts. The purpose present study was to evaluate FDS on humans, clinically and histologically. Ten two free (FG) were performed ten patients, them receiving both FG grafts. Clinical measurements made before surgery, immediately...

10.1902/jop.1983.54.8.463 article EN Journal of Periodontology 1983-08-01

BACKGROUND The treatment of complex tumors in non-functioning renal transplants requiring surgical extirpation is challenging. Here, we report the largest series patients who underwent transplant radical nephrectomy for cell carcinoma (RCC) and nephroureterectomy urothelial (UCC) their transplanted kidneys. MATERIAL AND METHODS From 2004 to 2018, 10 (7 patients) (3 patients). Retrospective analyses, terms complications, oncological recurrence, survival, peri-operative long-term outcomes,...

10.12659/aot.925865 article EN Annals of Transplantation 2020-10-23

<b><i>Introduction:</i></b> In this study we analyzed major histocompatibility complex class I (MHCI) expression as a potential prognostic immune marker for patients with clear cell renal carcinoma (ccRCC). <b><i>Patients and Methods:</i></b> 34 localized ccRCC (pT1-pT3) who had undergone nephrectomy at least 4 years of clinical follow-up data were included in the study. Immunohistochemical staining MHCI was performed on tumor sections. An...

10.1159/000370164 article EN Urologia Internationalis 2015-01-01

10.1016/s0140-6736(00)81801-2 article FR ˜The œLancet 1934-09-01

You have accessJournal of UrologyCME1 May 2022PD48-04 RECURRENT CURVATURE AFTER CORPOROPLASTY WITH TUNICA VAGINALIS FLAP: AN ANALYSIS OF BOYS WHO UNDERWENT VENTRAL PENILE LENGTHENING FOR PROXIMAL HYPOSPADIAS Kathy Huen, Amanda Macaraeg, Carol Davis-Dao, Sarah Holzman, Timothy Boswell, Zayn Suhale, Kai-Wen Chuang, Heidi Stephany, Elias Wehbi, and Antoine Khoury HuenKathy Huen More articles by this author , MacaraegAmanda Macaraeg Davis-DaoCarol Davis-Dao HolzmanSarah Holzman BoswellTimothy...

10.1097/ju.0000000000002616.04 article EN The Journal of Urology 2022-04-07

You have accessJournal of UrologyKidney Cancer: Evalution/Staging III1 Apr 2014MP36-03 MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I EXPRESSION IN CLEAR CELL RENAL CARCINOMA: CORRELATION WITH CLINICAL OUTCOME Sarah Holzman, Adeboye Osunkoya, Brian Pollack, Kenneth Ogan, and Viraj Master HolzmanSarah Holzman More articles by this author , OsunkoyaAdeboye Osunkoya PollackBrian Pollack OganKenneth Ogan MasterViraj View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.1067AboutPDF...

10.1016/j.juro.2014.02.1067 article EN The Journal of Urology 2014-03-28

541 Background: Most patients with clear cell renal carcinoma (ccRCC) initially present localized disease but a fraction subsequently develop metastases. Current predictive models of ccRCC recurrence are imperfect, suggesting need for additional predictors. Metastatic may be modulated by the immune system, that system plays role in tumor progression. Major histocompatibility complex class I (MHC I) expression on cells is critical recognition. Here, we analyzed MHC and its correlation...

10.1200/jco.2014.32.4_suppl.541 article EN Journal of Clinical Oncology 2014-02-01

469 Background: After nephrectomy for clear cell renal carcinoma (ccRCC) approximately one-third of patients develop metastases. Yet, with currently used prognostic tools such as the TNM staging and Fuhrman nuclear grade (FNG) system, it is difficult to accurately assess prognosis each patient. Here, we evaluated Major Histocompatibility Complex Class I (MHCI) expression a potential immune marker in ccRCC. Methods: Fifty-five post-nephrectomy that presented localized ccRCC were included. All...

10.1200/jco.2015.33.7_suppl.469 article EN Journal of Clinical Oncology 2015-03-01
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