A5039828061- Acute Myeloid Leukemia Research
- Hemoglobinopathies and Related Disorders
- Blood disorders and treatments
- Hematopoietic Stem Cell Transplantation
- Bone and Joint Diseases
- COVID-19 Clinical Research Studies
- Childhood Cancer Survivors' Quality of Life
- Bone health and treatments
- Iron Metabolism and Disorders
- Immunodeficiency and Autoimmune Disorders
- Celiac Disease Research and Management
- Platelet Disorders and Treatments
- Pharmacological Effects and Toxicity Studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Blood groups and transfusion
- Neonatal Health and Biochemistry
- Parvovirus B19 Infection Studies
- Neutropenia and Cancer Infections
- Respiratory viral infections research
- Streptococcal Infections and Treatments
- Vascular Anomalies and Treatments
- Retinopathy of Prematurity Studies
- Erythropoietin and Anemia Treatment
- Heparin-Induced Thrombocytopenia and Thrombosis
Istanbul Yeni Yüzyıl University
2019-2024
Diyarbakır Askeri Hastanesi
2018-2022
Sağlık Bilimleri Üniversitesi
2022
Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi
2022
Pamukkale University
2015-2018
Ümraniye Eğitim ve Araştırma Hastanesi
2014-2015
Ifosfamide (IFO) is an alkylating agent used to treat broad range of malignancies. One the life-threatening toxic effects reversible neurotoxicity. In this report; we presented a case report ifosfamide induced encephalopathy (IIE) in child with osteosarcoma order emphize that it important continue treatment as well importance potentially fatal complication.Following 20th week treatment, patient's follow-up diagnosis developed neurological findings. Laboratory analyzes before and after...
Abstract Background The aim of this study was to assess the impact serum panel reactive antibodies (PRA) on outcomes allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric thalassemia patients. Methods A total 73 patients with were included single‐center study. Pre‐transplant PRA levels evaluated, and divided into two groups: PRA‐negative (group 1; n = 44) PRA‐positive 2; 29). Patient characteristics, including age, gender, donor type, source, HLA compatibility, analyzed....
Summary Introduction We evaluated that response to parenteral iron therapy could be helpful in distinguishing the types of deficiency anemia. Patients and Methods This study analyzed responses IV sucrose 15 children with unexplained refractory anemia ( URIDA ). compared results at diagnosis, 6 weeks months after therapy. Results were 11 patients’ iron‐refractory IRIDA ) from our previous study. Result Six start treatment, ferritin, MCV , MCH Hb values normal range 10 patients. The increase...
Adenovirus is an infectious viral agent that causes variety of clinical presentations such as respiratory disease, conjunctivitis, and gastroenteritis.Hepatitis, pancreatitis, myocarditis, encephalitis, disseminated infection are primarily seen in immunocompromised patients.Rarely, adenovirus can present with pertussis-like syndrome.Described here case syndrome associated presenting hyperleukocytosis.
The aim of this study was to evaluate the severity hematological findings according etiology in patients with pancytopenia and bicytopenia.Patients bicytopenia who were examined Diyarbakir Children Hospital Pediatric Hematology Oncology clinic between June 2017-June 2018 evaluated retrospectively.Of 130 included study, 73 (56.2%) male 43 (43.8%) female. mean age 4.9 ± 4.86. Forty-five (34.6%) had 85 (65.3%) bicytopenia. youngest patient 1-month old oldest 18-year-old. blood count parameters...
TC Istanbul Yeni Yuzyil University Faculty of Medicine Pediatric Hematology Oncology, Hematopoetic Stem Cell Transplant Unit, Istanbul, Turkey The authors declare no conflict interest.
Introduction: in this study, it is aimed to emphasize the causes and importance of macrocytosis paediatric practice.
Thrombocytosis is a frequently seen condition during childhood. While it usually develops secondarily due to reasons such as infection or anemia, may rarely develop clonal causes. becomes life-threatening by causing severe complications hemorrhage and thrombosis development. Treatment not recommended in patients who are asymptomatic with platelet count below 1,500,000/mm3, however, treatment required cases symptomatic above 1,500,000/mm3 conditions primary thrombocytosis. This article...
Data on the risk factors and outcomes for pediatric patients with SARS-CoV-2 infection (COVID-19) following hematopoietic stem cell transplantation (HSCT) are limited. The study aimed to analyze clinical signs, factors, ICU admission mortality in a large cohort who underwent allogeneic HSCT prior COVID-19 infection. In this nationwide study, we retrospectively reviewed data of 184 recipients had between March 2020 August 2022. median time from was 209.0 days (IQR, 111.7-340.8; range, 0-3845...
Celiac disease (CD) is an immunological disorder. Clinical manifestations occur as a result of intestinal mucosa damage and malabsorption. CD also associated with extraintestinal autoimmune disorders. The coexistence diseases has been described before. In this article, patient presenting thrombocytopenia discussed.
OBJECTIVE:Celiac disease (CD) and Immune thrombocytopenic purpura (ITP) may occur together as a result of similar autoimmune mechanisms.The aim this study was to assess the frequency CD in group ITP patients literature. METHODS: A total 29 Pamukkale University Faculty Medicine Hospital Pediatric Hematology andOncology Department with were included study.Test performed for antibodies related CD.Positive celiac confirmed biopsy.The results compared RESULTS:Of group, 13 (44.8%) female 16...
Background: Various hematological disorders and malignancies may be encountered with Down syndrome. In this article, findings of children syndrome were investigated.Methods: The results 106 aged 3 months to 17 years assessed retrospectively. compared a patient group consisting non-DS healthy similar age range.Results: When the control group, significant difference was found between frequencies neutropenia, monocytosis, macrocytosis anisocytosis. No detected patients those without when...
Introduction:In this study, the hematologic findings of patients who were diagnosed with H1N1 virus infection and their effects on course disease reviewed. Method: Twenty-one children received diagnosis H1N1infection included in study.Blood count results days 1, 3 7 examined.The frequency 1 st day was compared those groups same age number patients.Time onset prognostic evaluated.Results: Seven 21 (33.3%) female, 14 (66.7%) male.The mean 5.1 years.Seven had leukopenia, (14.3%)had...
Deferasirox is an iron chelator that used in B-thalassemia worldwide. Nephrotoxicity one of the common side effects deferasirox. can be seen form nephritis and tubulopathy. A 6-year-old male whose ferritin levels were above 3500 ng/mL reported this article. was increased from 30 mg/kg/day to 40 because high ferritin. In complete urinalysis patient after 3 weeks later +3 protein detected, spot urine protein/creatinine ratio 2.5. without symptoms findings, deferasirox discontinued. his...
Background: Infections and nutritional deficiencies are the most common causes of leucopenia neutropenia. In this study, we aimed to find incidence vitamin B12 deficiency in patients with leukopenia neutropenia secondary infection.Methods: Between September 2018 December 2018, who were referred Diyarbakır Children Hospital's Pediatric Hematology Oncology Clinic for and/ or thought develop infection retrospectively evaluated.Results: Of 60 that evaluated, 23(38.3%) female 37(61.7%) male. The...
Purpose: Immune thrombocytopenia (ITP) is one of the most common hematologic disorders in childhood. Approximately 20-25% patients with newly diagnosed ITP become chronic. We aimed to investigate risk factors that may affect chronicity ITP. Materials and methods: A total 75 pediatric who were admitted Pediatric Hematology Department Pamukkale University Faculty Medicine Hospital between January 2013 July 2018 included study. 17 cases excluded, because 13 those had lack data system 4...
BACKGROUND/AIMS: Although advances for treating beta-thalassemia major have improved the survival of patients, endocrine complications are still quite common in these patients.These continue to negatively affect and quality life patients with thalassemia major.This study aimed determine frequency distribution investigate relationship between serum ferritin levels children adolescents followed up diagnosis MATERIALS AND METHODS: Fifty-eight (female/male: 27/31, mean age 12.6±5.16years)...
Introduction: Jeune syndrome affects an estimated 1 in 100.000 to 130.000 people. The causes breathing disorders and upper or lower respiratory tract infections because of thoracic cage which is smaller narrower than usual. Case: Here we report a male newborn presented with narrow short limbs. Radiological evaluation PA chest graphy showed abnormal ribs. 3D CT decreased antero-posterior diameter cavity, horizontally located round ended ribs, shallow acetabular cavity. Abdomen...
<h3>Background and aims</h3> Normal hearing in early infancy is essential forspeech, language, social emotional development of human beings. Congenital loss has an impact on normal speech language. Newborn screenings been proposed for the diagnosis treatment infants with loss, thereby improve language outcomes these babies. Our aim was to evaluate relationships between risk factors impairment auto acoustic emission (OAE) auditory brainstem responses (ABR) results patient’s follow-up at...
ÖZLeishmaniasis, sıklıkla 5 yaş altında görülen retiküloendotelyal sistemi tutan enfeksiyon hastalığıdır.Visseral enfeksiyon, uzun süreli ateş, kilo kaybı, halsizlik, pansitopeni, hepatosplenomegaliye sebep olabilir.Türkiye'de Visseral Leishmaniasis'ten (VL) sorumlu etken Leishmania infantum'dur.Bu yazıda İndirekt Floresan
GirişÇocukluk çağı akut lösemilerinde olaysız sağkalım %80-90 oranındadır.Buna rağmen uzun dönemde yaşam kalitesinin azalması ilaç toksisitesinin kronik etkileri ile ilgilidir (1).Osteonekrozis bu komplikasyonlardan biri olup sıklığı %1,6-9,3 arasındadır (2).Osteonekrozis, yük binen eklemlerde daha fazla olmak üzere, eklem fonksiyon bozukluğu ve izleminde günlük aktivitesinde azalma olarak tanımlanmaktadır.Klinik, sessiz başlayıp zamanla tutulan ağrı, hareket kısıtlılığı şişliği