A5100670013- Sarcoma Diagnosis and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipokines, Inflammation, and Metabolic Diseases
- Metabolism, Diabetes, and Cancer
- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
- Gastric Cancer Management and Outcomes
- Diet, Metabolism, and Disease
- Advancements in Battery Materials
- Pancreatic function and diabetes
- Head and Neck Surgical Oncology
- Management of metastatic bone disease
- Blood Pressure and Hypertension Studies
- Diverticular Disease and Complications
- Cancer Cells and Metastasis
- Pancreatic and Hepatic Oncology Research
- Advanced Battery Materials and Technologies
- Colorectal and Anal Carcinomas
- Heart Rate Variability and Autonomic Control
- Cardiovascular and exercise physiology
- Abdominal vascular conditions and treatments
- Ocular Oncology and Treatments
- Diabetes Treatment and Management
- Urinary and Genital Oncology Studies
- Renal and Vascular Pathologies
National Defense Medical Center
2012-2025
Tri-Service General Hospital
2009-2025
National Tsing Hua University
2024
Cardinal Tien Hospital
2011-2022
Weatherford College
2022
Fu Jen Catholic University
2011-2021
Taoyuan Armed Forces General Hospital
2015-2021
Changhua Christian Hospital
2021
Catholic University of America
2021
Massachusetts General Hospital
2016-2020
Background/Objectives: Gastric cancer is one of the most common and lethal cancers worldwide, with particularly high incidence mortality rates in East Asia Europe. DNAJB4 has been shown to have prognostic implications other types; however, its expression patterns role gastric not extensively studied. This study aimed analyze explore association clinical characteristics, molecular markers, patient outcomes. Methods: We selected suitable tumor samples from 189 patients who had undergone...
Scope Several beneficial biological functions of fucoidan (FO) isolated from brown algae have been demonstrated. The purpose this study was to investigate whether FO derived Sargassum hemiphyllum ameliorates pancreatic β‐cell damage and impaired insulin synthesis under diabetic condition. Methods results effects were studied in streptozotocin (STZ)‐treated line, NIT‐1cells, mice. cell apoptosis, protein analyses, histological examination, function assays performed. increased apoptosis...
Sodium-ion batteries with P2-type layered transition metal oxides (NaxTMO2) as cathode materials hold promise for large-scale energy storage due to their cost-effectiveness and high operating voltage. However, achieving the theoretical capacity is challenging limitations of electrode materials. To overcome this challenge, a K-doped Na0.67Mg2/9Mn2/3Cu1/9O2 material was developed in study enhance electrochemical performance suppress structural evolution. Synthesized via sol–gel method,...
Recently, log odds of positive lymph nodes (LODDS) was proven a better prediction outcomes than other methods in gastric cancer, pancreatic and colon cancer. However, the validity is not yet tested oral cavity squamous cell carcinoma (OSCC). We conducted retrospective study to compare predictive ability LODDS, traditional pN classification node ratio (rN) OSCC patients. In total, 347 patients receiving surgery with or without adjuvant therapy at time diagnosis between 2004 2013 were...
The urine albumin-creatinine ratio (uACR) is a warning for the deterioration of renal function in type 2 diabetes (T2D). early detection ACR has become an important issue. Multiple linear regression (MLR) traditionally been used to explore relationships between risk factors and endpoints. Recently, machine learning (ML) methods have widely applied medicine. In present study, four ML were predict uACR T2D cohort. We hypothesized that (1) outperforms traditional MLR (2) different ranks...
The concept of using single criterion normal blood pressure with systolic (SBP) < 140 mmHg and diastolic (DBP) 90 for all ages is still disputable. aim the study to identify cutoff value normotension in different age sex groups. Totally, 127,922 (63,724 men 64,198 women) were enrolled analysis. Finally, four fifths them randomly selected as group other one validation group. Due tight relationship comorbidities from cardiovascular disease (CVD), metabolic syndrome (MetS) was used a surrogate...
Learning points for cliniciansCOVID-19 vaccine-induced thrombosis with thrombocytopenia syndrome (TTS) has been reported as a very rare complication after the ChAdOx1 nCoV-19 (AstraZeneca) vaccination and usually manifesting cerebral venous or pulmonary artery embolism.In comparison stroke embolism, TTS associated intra-abdominal is less common.Early identification timely treatment are required.
Metabolic syndrome's (MetS) role in predicting cardiovascular diseases and diabetes has been confirmed many large cohort studies. Nontraditionally, hematogram components are significantly related to MetS different age groups. However, little is known about its among the elderly.We enrolled 18,907 subjects over of 65 years who underwent regular health examinations. They were divided into three groups according age: young old (YO: ≥ < 74 old), (OO: 75 84 oldest (ODO: 85 old). The determined,...
Although primary gastrointestinal lymphoma is a rare malignancy, it can cause an intussusception in adults and be clinically challenging condition to manage.Intussusception could progress lifethreatening complications if left untreated or delay chemotherapy inappropriate surgical management used.We report 31-year-old man diagnosed with human immunodeficiency virus who was being treated antiretroviral therapy.He presented nausea, vomiting, poor appetite, intermittent, cramping abdominal pain...
A 59-year-old man presented with persistent urinary obstructive symptoms, gross hematuria, and mucusuria. Subsequently, a prostate-specific antigen (PSA)-negative mucin-producing urothelial type adenocarcinoma of prostate was found. The serum PSA level within the normal limit. Colonoscopy, positron emission tomography, other tumor surveys showed this to be only lesion. Microscopically, there an copious mucin production, formation pools. neoplastic glands were variously arranged in...
A carcinoma ex pleomorphic adenoma (CXPA) is an epithelial malignancy arising in or from a benign salivary adenoma. The parotid gland the most common location of CXPAs. Minor CXPAs nasal cavity are exceedingly rare, with only 6 documented literature.We present 7th case: unusual pedunculated intranasal CXPA, which had favorable outcome after wide endoscopic excision and longest follow-up period reported to date. clinical features, immunohistochemical characteristics, treatment choices,...
Colorectal cancer (CRC) is one of the most common cancers and results in high mortality worldwide, owing to progression, i.e., metastasis. However, molecular mechanism underlying metastatic evolution CRC remains largely unknown. Here, we find that upregulation Ral Guanine Nucleotide Dissociation Stimulator Like 2 (RGL2) commonly detected primary tumors compared normal tissues significantly associated with a poorer prognosis patients. Moreover, RGL2 expression appeared positively correlate...
Amyand's hernia is a rare form of inguinal in which an inflamed appendix incarcerated hernial sac. The clinical presentation varies, depending on the extent inflammation involved sac and presence or absence scrotal abscess. If abscess present, this usually indicates that perforated. However, without availability computed tomography (CT) scans, condition often preoperatively misdiagnosed as strangulated hernia. We describe case 64-year-old man who presented at our emergency room complaining...
Serum gamma-glutamyltransferase (γ-GT) is implicated in the pathogenesis of atherosclerosis and metabolic syndrome (MetS) adults. The relationships between γ-GT cardiometabolic dysregulation remains unclear adolescents. We enrolled 7,072 Taiwanese adolescents followed them for a median 6.8 years. optimal cut-off values (CoVs) baseline to predict future MetS, hypertension (HTN), type 2 diabetes (T2DM) were determined by receiving operating characteristic (ROC) curve. Using these CoVs,...
Type 2 diabetes mellitus (T2DM) patients have a high risk of coronary artery disease (CAD). Thallium-201 myocardial perfusion scan (Th-201 scan) is non-invasive and extensively used tool in recognizing CAD clinical settings. In this study, we attempted to compare the predictive accuracy evaluating abnormal Th-201 scans using traditional multiple linear regression (MLR) with four machine learning (ML) methods. From can determine whether ML surpasses MLR rank variables them previous reports.In...
1519 Background: Angiosarcoma (AS) is a rare soft tissue sarcoma, with an incidence of 300/yr and 5-year DSS 30%. The low has impeded large-scale research efforts that may lead to improved clinical outcomes. To address this, we launched nationwide study, which seeks empower patients (pts) accelerate by sharing their samples information remotely. Methods: With pts advocacy groups developed website allow AS participate across the US. Pts are mailed saliva blood draw kit for germline cell free...
Aim: Elevated levels of C-reactive protein (CRP) and alanine aminotransferase (ALT) are tightly associated with metabolic syndrome (MetS). However, it is unclear whether the combination normal CRP ALT increases probability presence MetS. Materials Methods: We enrolled 433 Chinese in health screening both range. They were divided into four groups: low (BL, baseline ALT), only high (HCRP), (HALT), (BH, ALT) different genders. The receiver operating characteristic curve was used for comparing...