M. Vimalin Jeyalatha

ORCID: 0000-0002-6414-8675
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About
Contact & Profiles
Research Areas
  • Corneal Surgery and Treatments
  • Ocular Surface and Contact Lens
  • Corneal surgery and disorders
  • Advanced Glycation End Products research
  • Ocular Diseases and Behçet’s Syndrome
  • Ocular Infections and Treatments
  • Glaucoma and retinal disorders
  • Mycobacterium research and diagnosis
  • Peripheral Neuropathies and Disorders
  • Wound Healing and Treatments
  • Facial Rejuvenation and Surgery Techniques
  • Air Quality and Health Impacts
  • Nanoparticles: synthesis and applications
  • Tuberculosis Research and Epidemiology
  • Tannin, Tannase and Anticancer Activities
  • dental development and anomalies
  • RNA Interference and Gene Delivery
  • Multiple Sclerosis Research Studies
  • Sinusitis and nasal conditions
  • Nasolacrimal Duct Obstruction Treatments
  • Medicinal Plant Research
  • Immunotherapy and Immune Responses
  • Hedgehog Signaling Pathway Studies
  • Ocular Disorders and Treatments
  • Glycosylation and Glycoproteins Research

Xiamen University
2017-2022

Sankara Nethralaya
2011-2022

Larsen & Toubro (India)
2022

Birla Institute of Technology and Science, Pilani
2014-2015

Oil and Natural Gas Corporation (India)
2015

Medical Research Foundation
2015

To determine if a high-fat diet (HFD) induces meibomian gland (MG) inflammation in mice.Male C57BL/6J mice were fed standard (SD), HFD, or HFD supplemented with the peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist rosiglitazone for various durations. Body weight, blood lipid levels, and eyelid changes monitored at regular intervals. MG sections subjected to hematoxylin eosin staining, LipidTox TUNEL assay, immunostaining. Quantitative RT-PCR western blot analyses performed...

10.1167/iovs.62.10.13 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2021-08-16

Purpose: To investigate a novel strategy in constructing tissue-engineered corneal stromal equivalent based on amniotic membrane and keratocytes. Methods: The ultrathin (UAM) was laminated, with cells (CSCs) distributed between the space of layered UAMs. Calcein AM staining used to evaluate cellular viability, morphology, arrangement. Immunostaining, qRT-PCR, Western blot were performed detect gene protein expression Optical coherence tomography visualized cross sections thickness UAM...

10.1167/iovs.18-24869 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2019-02-01

Abstract Amniotic membrane (AM) has been widely used as a temporary or permanent graft in the treatment of various ocular surface diseases. In this study, we compared epithelial wound healing and tissue remodeling after reconstruction with intact amniotic (iAM) denuded (dAM). Partial limbal bulbar conjunctival removal was performed on New Zealand rabbits followed by transplantation cryo-preserved human iAM dAM. vivo observation showed that ingrowth faster dAM to AM transplantation....

10.1038/s41598-018-24694-4 article EN cc-by Scientific Reports 2018-04-17

A novel probe, based on vancomycin and 4-nitrobenzoxadiazole was synthesized characterized, used for the rapid specific detection of Gram positive bacteria – major pathogens responsible eye infections in ocular specimens.

10.1039/d2sd00061j article EN cc-by Sensors & Diagnostics 2022-01-01

Uveitis develops as a late complication of leptospirosis in 40% patients and often occurs year after acute illness.1 Since number microbial pathogens autoimmune diseases are associate...

10.3109/09273948.2011.592259 article EN Ocular Immunology and Inflammation 2011-08-11

Background: Uncontrolled collagen degradation is the characteristics of keratoconus.Degradation type 1 releases telopeptides.The role telopeptides on apoptosis corneal stromal cells have not been studied so far.Methods: Human primary was cultivated and treated with varying concentrations synthetic (3.012µg, 6.125µg, 12.25µg, 23.5µg, 47µg 94µg) incubated for 24 hours, 48 hours 72 hours.MTT TUNEL assay performed following incubation.The difference between number viable present in untreated...

10.9734/or/2014/12138 article EN Ophthalmology Research An International Journal 2014-01-10

Proteins and antigens present on the cell surface are usually determined by immunofluorescence staining. Uniform distribution of cells is required to appreciate presence proteins. Improper smearing or crushing corneal epithelial can potentially destroy cellular integrity. Thus a simplified, systemic method was designed smear scraped from cornea. The procedure includes trypsinisation for dissociation cytospinning concentrating in smear. standardized protocol found be efficient maintaining...

10.1097/pai.0000000000000168 article EN Applied immunohistochemistry & molecular morphology 2015-12-02

10.1016/s0002-9440(20)30029-8 article EN publisher-specific-oa American Journal Of Pathology 2020-03-01

Here, we communicate the draft genome sequence of an ocular Mycobacterium tuberculosis strain (SNMICRO 2047-20) that was isolated from vitreous fluid a patient diagnosed with endophthalmitis. The 4,391,538 bp long 3,898 protein-encoding genes and clustered to East African-Indian lineage.

10.1128/mra.00791-22 article EN Microbiology Resource Announcements 2022-12-21
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