A5005942463- Dementia and Cognitive Impairment Research
- Geriatric Care and Nursing Homes
- Frailty in Older Adults
- Health Systems, Economic Evaluations, Quality of Life
- Health disparities and outcomes
- Palliative Care and End-of-Life Issues
- Pharmaceutical Practices and Patient Outcomes
- Health and Well-being Studies
- Older Adults Driving Studies
- Intergenerational Family Dynamics and Caregiving
- Chronic Disease Management Strategies
- Emergency and Acute Care Studies
- Health Policy Implementation Science
- Urban Transport and Accessibility
- Family and Patient Care in Intensive Care Units
- Intensive Care Unit Cognitive Disorders
- Cancer survivorship and care
- Health and Medical Research Impacts
- Cancer-related cognitive impairment studies
- Family Caregiving in Mental Illness
- Technology Use by Older Adults
- Ethics in Clinical Research
- Mental Health and Patient Involvement
- Patient-Provider Communication in Healthcare
- Health Sciences Research and Education
Indiana University – Purdue University Indianapolis
2016-2025
Regenstrief Institute
2016-2025
Indiana Clinical and Translational Sciences Institute
2019-2025
Indiana University School of Medicine
2015-2025
Indiana University
2015-2025
Indiana University Indianapolis
2015-2025
Case Western Reserve University
2022-2024
University School
2018-2024
University Hospitals of Cleveland
2022-2024
Birmingham and Solihull Mental Health NHS Foundation Trust
2024
Abstract Introduction Mild cognitive impairment remains substantially underdiagnosed, especially in disadvantaged populations. Failure to diagnose deprives patients and families of the opportunity treat reversible causes, make necessary life lifestyle changes receive disease‐modifying treatments if caused by Alzheimer's disease. Primary care, as entry point for most, plays a critical role improving detection rates. Methods We convened Work Group national experts develop consensus...
The benefits and harms of screening Alzheimer disease related dementias (ADRDs) are unknown. This study addressed the question whether outweigh for ADRDs among older adults in primary care.Single-blinded, two-arm, randomized controlled trial (October 2012-September 2016) urban, suburban, rural care settings Indiana. A total 4005 patients (aged ≥65 years) were to ADRD (n = 2008) or control 1997).Patients screened using Memory Impairment Screen Mini-Cog referred a voluntary follow-up...
Objectives To determine individuals’ perceptions concerning dementia screening and to evaluate the possibility of an association between their willingness undergo screening. Design Cross‐sectional study primary care patients aged 65 older. Setting Urban clinics in Indianapolis, Indiana, 2008 2009. Participants Five hundred fifty‐four without a documented diagnosis dementia. Measurements The Perceptions Regarding Investigational Screening for Memory Primary Care Questionnaire ( PRISM ‐ PC )...
Background/Objectives Post‐marketing comparative trials describe medication use patterns in diverse, real‐world populations. Our objective was to determine if differences rates of adherence and tolerability exist among new users acetylcholinesterase inhibitors ( AC h EI 's). Design Pragmatic randomized, open label trial 's currently available the United States. Setting Four memory care practices within four healthcare systems greater Indianapolis area. Participants Eligibility criteria...
Examine the feasibility, acceptability, and preliminary effects of Telephone Acceptance Commitment Therapy Intervention for Caregivers (TACTICs) on dementia caregivers' anxiety, depression, caregiver burden, suffering, anticipatory grief. A 2-arm pilot randomized trial with caregivers ≥ 21 years old clinically elevated anxiety or anxiety-related functional interference. Two cohorts were recruited at beginning end first year COVID-19 pandemic. participants received 6 telephone sessions...
Abstract Background Participant recruitment and retention are critical to the success of clinical trials, yet challenges such as low enrollment rates high attrition remain ongoing obstacles. RecruitGPS is a scalable dashboard with integrated control charts address these issues by providing real-time data monitoring analysis, enabling researchers better track improve retention. Objective This study aims identify inefficiencies users encounter when interacting dashboard. By identifying issues,...
The number of people with dementia is expected to grow substantially across the world due population aging, but cognitive impairment remains undetected and undiagnosed, especially in early stages. Newly available diagnostic tools such as digital assessments blood biomarker tests may be well suited increase rates detection primary care. objective Davos Alzheimer's Collaborative Healthcare System Preparedness (DAC-SP) Early Detection Flagship Program was improve rate care non-specialty...
Abstract The Alzheimer’s Disease in Older Adults with Chronic Conditions (ADACC) Network is funded by the National Institute on Aging as a U24 cooperative agreement. ADACC an inclusive, multidisciplinary group across multiple institutions that charged task of developing evidence-based strategies for use and implementation disease related dementias (AD/ADRD) biomarkers among older adults cognitive impairment chronic conditions (MCCs). This report summarizes highlights First Annual Symposium...
Background An Alzheimer's disease (AD) diagnosis made in the earliest symptomatic stages substantially benefits patients and their care partners. However, little is known regarding clinical, healthcare system-level, patient-specific barriers that hinder timely treatment. Objective To explore real-world practices surrounding diagnostic journey management of mild cognitive impairment (MCI)/AD dementia patients. Methods Data were drawn from Adelphi Real World Dementia Disease Specific...
Abstract INTRODUCTION It is unknown how prepared primary care practices are to deliver recommended dementia care. METHODS A nationally representative survey of US focused on delivery processes, including those for patients with Alzheimer's disease and related dementias (ADRD). RESULTS total 1245 3498 (36%) responded. Most reported systems detect ADRD (67%) refer diagnostic testing (75%). Fewer required ADRD‐related training (45%–46%) or maintained an registry (29%). Practices that scored...
Background The 5-Cog paradigm is a 5-minute brief cognitive assessment coupled with clinical decision support tool designed to improve clinicians’ early detection of impairment, including dementia, in their diverse older primary care patients. battery uses picture- and symbol-based assessments questionnaire. It low cost, simple, minimizes literacy bias, culturally fair. component the helps nudge appropriate provider response an abnormal battery. Objective objective our study evaluate...
Objective . To understand older primary care patients’ perceptions of the risks and benefits dementia screening to measure association between attitudes behaviors. Methods Eligible patients completed Perceptions Regarding Investigational Screening for Memory in Primary Care (PRISM-PC) questionnaire then were asked undergo by a telephone instrument. Results Higher scores on PRISM-PC items that about associated with decreased odds refusing screening. Participants who refused had significantly...
Objectives To examine racial and ethnic differences in initiation time to discontinuation of antidementia medication Medicare beneficiaries. Design Retrospective cohort study. Setting Secondary analysis 2009–10 enrollment, claims, Part D prescription data for a 10% national sample U.S. fee‐for‐service Participants Beneficiaries aged 65 older with Alzheimer's disease or related dementia ( ADRD ) before 2009 no fills medications the first half (N = 84,043). Measurements Initiation was defined...
Abstract Background and Objectives To identify the implementation barriers, facilitators, conditions associated with successful outcomes from a clinical demonstration project to reduce potentially avoidable hospitalizations of long-stay nursing facility residents in 19 Indiana homes. Research Design Methods Optimizing Patient Transfers, Impacting Medical quality, Improving Symptoms—Transforming Institutional Care (OPTIMISTIC) is multicomponent intervention that includes enhanced geriatric...
Abstract Background Caregivers of patients with Alzheimer’s disease or a related dementia (ADRD) report high levels distress, including symptoms anxiety and depression, caregiving burden, existential suffering; however, those support healthy coping strategies have less stress burden. Acceptance Commitment Therapy (ACT) aims to foster greater acceptance internal events while promoting actions aligned personal values increase psychological flexibility in the face challenges. The objective this...
To examine the effect of Medicare Annual Wellness Visit (AWV) on detection cognitive impairment and follow-up care for older adults.Retrospective matched-cohort study.United States.A 5% random sample fee-for-service beneficiaries continuously enrolled 12 months before after an index ambulatory visit occurring from 2011 to 2013 with no claims evidence index.Outcomes include 12-month post-index claims-based measurements impairment, including new Alzheimer's disease related dementia (ADRD)...
Background In today’s digital age, web-based apps have become integral to daily life, driving transformative shifts in human behavior. “AgileNudge+” (Indiana University Center for Health Innovation and Implementation Science) is a solution simplify the process of positive behavior change using nudging as an intervention. By integrating knowledge from behavioral economics with technology, AgileNudge+ organizes multiple steps, simplifies complex tasks, minimizes errors by enhancing user...
Measure perceived involvement in medical decision making and determine if anticipatory grief is associated with problem solving among family caregivers of older adults cognitive impairment.Retrospective analysis baseline data from a caregiver intervention (n = 73). Multivariable regression models testing the association between caregivers' grief, measured by Anticipatory Grief Scale (AGS), problem-solving abilities, social inventory-revised: short form (SPSI-R: S).47/73 (64%) reported...
Considering limited data exploring reimbursement trends at the subspecialty level within head and neck surgical oncology, we sought to characterize these for neck-specific codes from 2000 2020.Using Centers Medicare Medicaid Services' Physician Fee Schedule Look-Up Tool, data, adjusted 2020 U.S. dollars, 37 oncologic procedure were collected 2020.From 2020, despite gross all procedures increasing by 23.2%, when inflation, physician decreased 19.4%. Only 4 of examined increased in net over...
Abstract Background As part of the debate about screening for dementia, it is critical to understand why patients agree or disagree diagnostic assessment after a positive test. We used Perceptions Regarding Investigational Screening Memory in Primary Care (PRISM‐PC) questionnaire measure characteristics who screened dementia but refused further assessment. Methods Survey ≥65 years old without diagnosis attending primary care clinics Indianapolis, IN, 2008 and 2009. Results Five hundred...
Problem Despite the more than $32 billion National Institutes of Health has invested annually, evidence-based health care services are not reliably implemented, sustained, or distributed in delivery organizations, resulting suboptimal and patient harm. New organizational approaches frameworks that reflect complex nature systems needed to achieve this goal. Approach To guide implementation at their institution, authors used a number behavioral theories develop Agile Implementation (AI)...