A5088413538- Shoulder Injury and Treatment
- Orthopedic Surgery and Rehabilitation
- Osteoarthritis Treatment and Mechanisms
- Shoulder and Clavicle Injuries
- Cell Adhesion Molecules Research
- Glycosylation and Glycoproteins Research
- Nerve Injury and Rehabilitation
- Thermal Regulation in Medicine
- Infrared Thermography in Medicine
- Elbow and Forearm Trauma Treatment
- Foot and Ankle Surgery
- Knee injuries and reconstruction techniques
- Genetic and Kidney Cyst Diseases
- Gear and Bearing Dynamics Analysis
- Colorectal Cancer Treatments and Studies
- Hernia repair and management
- Gastric Cancer Management and Outcomes
- Angiogenesis and VEGF in Cancer
- Thermoregulation and physiological responses
- Hip and Femur Fractures
- Abdominal Surgery and Complications
- Heparin-Induced Thrombocytopenia and Thrombosis
- Periodontal Regeneration and Treatments
- Chemical Synthesis and Analysis
- Pediatric Hepatobiliary Diseases and Treatments
Otaru Municipal Hospital
2018-2023
Hokkaido University
2011-2019
Sapporo City General Hospital
2016
The University of Tokyo
2014
Rheumatoid arthritis (RA), a chronic systemic inflammatory disorder that principally attacks synovial joints, afflicts over 2 million people in the United States. Interleukin (IL)-17 is considered to be master cytokine chronic, destructive arthritis. Levels of ganglioside GM3, one most primitive glycosphingolipids containing sialic acid structure, are remarkably decreased synovium patients with RA. Based on increased secretions observed vitro experiments, GM3 might have an immunologic role....
Glycosphingolipids (GSLs) are ubiquitous membrane components that modulate transmembrane signaling and mediate cell-to-cell cell-to-matrix interactions. GSL expression is decreased in the articular cartilage of humans with osteoarthritis (OA). This study was undertaken to determine functional role GSLs metabolism related OA pathogenesis mice.We generated mice knockout chondrocyte-specific Ugcg gene, which encodes an initial enzyme major synthesis, using Cre/loxP system (Col2-Ugcg(-/-) mice)....
Abstract We developed an ultra‐purified in situ forming gel as injectable delivery vehicle of bone marrow stromal cells (BMSCs). Our objective was to assess reparative tissues treated with autologous BMSCs implanted using the implantation system into osteochondral defects a canine model. Forty‐eight patella groove knee joint were created 12 adult beagle dogs (two each knee). The divided defect group ( n = 16), acellular novel material (material) and current (material BMSCs) 16). at 16 weeks...
Objectives The purpose of this study was to investigate the nerve injury rate for 1 million venipunctures and efficacy attempts avoid severe injury. Methods We collected data outpatients from whom a venipuncture blood sample obtained in our hospital 2005 2014. Every procedure performed by trained nurse or clinical technologist at center sampling hospital. In addition, series lectures specialist is held various times. All complaints related were reported division safety management followed up...
We have developed an ultrapurified low endotoxin alginate (UPLE alginate), which can drastically reduce levels. Our purposes were to examine the effects of UPLE administration on osteoarthritis (OA) progression and determine adequate molecular weight for therapeutic effects.To induce knee OA, 35 Japanese White rabbits underwent anterior cruciate ligament transection. Intra-articular injections 0.3 mL solution each material started at 4 weeks postoperatively a total 5 weekly injections....
This study aimed to elucidate the therapeutic effects of intra-articular administration ultra-purified low endotoxin alginate (UPLE-alginate) on osteoarthritis (OA) using a canine anterior cruciate ligament transection (ACLT) model.We used 20 beagle dogs. ACLT was performed left knee each dog and sham operation right as control. All animals were randomly divided into control (saline) groups. Animals in groups received weekly injections with 0.7 mL normal saline or 0.5% UPLE-alginate,...
The aim of this study was to clarify the effects morphological patterns sigmoid notch on stress distribution across articular surface distal radioulnar joint using a computed tomography osteoabsorptiometry method. Fourteen wrists from 13 patients were classified into two groups according type notch, namely 'C' and ski-slope sigmoids, percentages high-density areas quantitatively analysed. percentage area dorsal region in group significantly greater than that (16% vs 4.1%) volar 2.4%)....
Shoulder injury related to vaccine administration, defined as shoulder pain and limited range of motion occurring after administration in the upper arm, has been previously reported. The symptom resolved completely treatment with oral nonsteroidal anti-inflammatory drugs or an intraarticular steroid injection, however there have few reports long-term symptoms following coronavirus disease 2019 vaccination. This case report describes a healthy, middle-aged, healthcare worker who developed...
We aimed to clarify the effects of morphological patterns trapezium and first metacarpal on distribution subchondral bone density across articular surface trapeziometacarpal (TMC) joint using computed tomography osteoabsorptiometry. Thirty-three patients with normal TMC joints were evaluated. The percentages high-density areas in radial-dorsal ulnar-volar regions significantly higher than that ulnar-dorsal region, region was lower other three regions. percentage area trapezial inclination...
Abstract We aimed to clarify the effects of morphological patterns trapezium and first metacarpal on stress distribution across articular surface trapeziometacarpal (TMC) joint using computed tomography osteoabsorptiometry. Thirty-three patients with normal TMC joints were evaluated. The percentages high-density areas in radial-dorsal ulnar-volar regions significantly higher than that ulnar-dorsal region, region was lower other three regions. percentage area trapezial inclination (TI) showed...
Traumatic or recurrent dislocation of the shoulder due to disruption anterior band inferior glenohumeral ligament (AIGHL) complex occurs in young and active populations.1Blasier R.B. Guldberg R.E. Rothman E.D. Anterior stability: Contributions rotator cuff forces capsular ligaments a cadaver model.J Shoulder Elbow Surg. 1992; 1: 140-150Abstract Full Text PDF PubMed Scopus (129) Google Scholar However, concomitance tears associated with traumatic increases advancing age.24Simank H.G. Dauer G....
Abstract In der ersten von vier aufeinanderfolgenden Arbeiten werden Synthesemöglichkeiten für 8ß‐substituierte Steroide beschrieben.