- Infant Nutrition and Health
- Appendicitis Diagnosis and Management
- Intestinal Malrotation and Obstruction Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Esophageal and GI Pathology
- Diverticular Disease and Complications
- Breastfeeding Practices and Influences
- Congenital Anomalies and Fetal Surgery
- Clinical Nutrition and Gastroenterology
- Abdominal Trauma and Injuries
- Gastrointestinal disorders and treatments
- COVID-19 and healthcare impacts
- Hip and Femur Fractures
- Trauma and Emergency Care Studies
- Gastroesophageal reflux and treatments
- Enhanced Recovery After Surgery
- Colorectal Cancer Surgical Treatments
- Child Nutrition and Feeding Issues
- Ultrasound in Clinical Applications
- COVID-19 Impact on Reproduction
- Global Health and Surgery
- Cancer and Skin Lesions
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
Imperial College Healthcare NHS Trust
2020-2023
Chelsea and Westminster Hospital NHS Foundation Trust
2009-2022
University of Göttingen
2022
University of Birmingham
2022
National Institute for Health Research
2022
University College London
2008-2020
Great Ormond Street Hospital
2008-2020
Great Ormond Street Hospital for Children NHS Foundation Trust
2017-2019
University of Liverpool
2016-2018
Countess of Chester Hospital
2016-2018
In Brief Objective: To determine whether primary peritoneal drainage improves survival and outcome of extremely low birth weight (ELBW) infants with intestinal perforation. Summary Background Data: Optimal surgical management ELBW perforation is unknown. Methods: An international multicenter randomized controlled trial was performed between 2002 2006. Inclusion criteria were birthweight ≤1000 g pneumoperitoneum on x-ray (necrotizing enterocolitis or isolated perforation). Patients to drain...
Strategies for the surgical management of necrotising enterocolitis are various and controversial.To characterise variation in this disease across United Kingdom.Postal survey 104 consultant paediatric surgeons with a 77% response rate.Duration antibiotic treatment (median 10 days, range 6-14), time until start enteral feeding 4-21), absolute indications surgery all vary between surgeons. Peritoneal drainage is used by 95% Forty two percent use it neonates weights, whereas 36% restrict its...
Probiotic administration to preterm infants has the potential prevent necrotising enterocolitis (NEC). Data from randomised controlled trials (RCT) are conflicting but meta-analyses seem support this intervention. To date, these analyses have not focused on surgical NEC. We aimed determine effect of probiotic prevention NEC.A systematic review RCTs was performed. Studies were included if RCT outcomes any (1) Bell's stage 3 NEC; (2) surgery for and (3) deaths attributable Article selection...
Objectives Acute appendicitis is the most common surgical condition in children. In UK, appendicectomy treatment with non-operative management unusual. Due to concerns about risk of SARS-CoV-2 transmission during procedures, surgeons were advised consider and avoid laparoscopy where possible. This study aims report outcomes, date, children UK Ireland COVID-19 pandemic. Design Survey consultant who treat that informed a prospective multicentre observational cohort study. Setting Data...
Abstract Background A major shift in treatment of appendicitis occurred early the SARS-CoV-2 pandemic with non-operative management used commonly outside research protocols and units limited previous experience. This study aims to compare real-world outcomes surgery versus uncomplicated children 1-year follow-up. Method prospective multicentre observational treated for at 74 hospitals UK Ireland from 1 April 31 July 2020 was performed. Propensity-score matched analysis conducted using age,...
Post-prandial hyperinsulinaemic hypoglycaemia (PPHH) is a recognized complication of various gastric surgeries in children, but rarely reported after oesophageal atresia repair. We report 2 children diagnosed with PPHH surgery and the challenges their management. Case 1: A 2-year-old boy at birth was surgically repaired requiring 6 dilatations first year life. At 11 months age, he manifested hypoglycaemic seizures investigations confirmed PPHH. Acarbose diazoxide trials failed. He managed...
To compare the reported and observed management of UK children with blunt liver or spleen injury (BLSI) to American Pediatric Surgical Association (APSA) 2019 BLSI guidance.UK Paediatric Major Trauma Centres (pMTCs) undertook 1 year prospective data collection on admitted discussed those centres an online questionnaire was distributed all consultants who care for in centres.All 21/21 (100%) pMTCs participated; 131 patients were included 100/152 (65%) responded survey. ICU be primarily...
Abstract Background The evidence base underlying clinical practice in children’s general surgery is poor and high-quality collaborative research required to address current treatment uncertainties. aim of this study was, through a consensus process, identify priorities for field amongst surgeons who treat children. Methods Questions were invited scoping survey specialist paediatric surgeons. These refined by the team subsequently prioritized two-stage modified Delphi process. Results In...