A5071950895- Metabolism and Genetic Disorders
- Autoimmune and Inflammatory Disorders Research
- Immunodeficiency and Autoimmune Disorders
- Mitochondrial Function and Pathology
- Skin Diseases and Diabetes
- Biomedical Research and Pathophysiology
- Lysosomal Storage Disorders Research
- Ion channel regulation and function
- Autoimmune Bullous Skin Diseases
- Systemic Sclerosis and Related Diseases
- Inflammatory Myopathies and Dermatomyositis
- Venomous Animal Envenomation and Studies
- Economic and Financial Impacts of Cancer
- Eosinophilic Disorders and Syndromes
- Autoimmune and Inflammatory Disorders
- Venous Thromboembolism Diagnosis and Management
- RNA modifications and cancer
- Pediatric Hepatobiliary Diseases and Treatments
- BRCA gene mutations in cancer
- Global Cancer Incidence and Screening
- Multiple and Secondary Primary Cancers
- Advances in Oncology and Radiotherapy
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Histiocytic Disorders and Treatments
- Viral-associated cancers and disorders
Hopital Universitaire Hedi Chaker
2016-2025
University of Sfax
2015-2025
Hôpital Farhat Hached
2012-2024
University of Sousse
2020-2024
General Department of Preventive Medicine
2023
Hôpital La Rabta
2019-2021
Habib hospital Thameur
2019
Hopital Universitaire Habib Bourguiba
2008-2013
Hôpital Saint-Vincent-de-Paul
2009
Inserm
2009
Our objective was to characterize both epidemiologically and clinically manifestations after severe scorpion envenomation define simple factors indicative of poor prognosis in children. We performed a retrospective study over 13 years (1990-2002) the medical intensive care unit (ICU) university hospital (Sfax-Tunisia). The diagnosis based on history sting. records 685 children aged less than 16 who were admitted for sting analyzed. There 558 patients (81.5%) grade III group (with cardiogenic...
Abstract Background Dihydrolipoamide dehydrogenase deficiency (DLDD) (OMIM# 246,900) is an extremely rare inherited metabolic disorder causing neurological and/or liver impairment. The clinical manifestations are mostly characterized by severe impairment in early childhood, hepatic presentations and rarely myopathic manifestations. Case Here, we describe two patients presenting with recurrent episodes of vomiting dysfunction. DLDD was confirmed via sanger sequencing identification the...
Abstract Aim: To investigate the previously unknown birth incidence, treatment, and mortality of children with congenital heart disease in Tunisia. Methods: We undertook a retrospective review medical records all patients who were born 2010 2011, diagnosed Sfax (Tunisia) defect. Results: Among 37,294 births, 255 detected to have disease, yielding incidence 6.8 per 1000. The most frequently occurring conditions ventricular septal defects (31%), ostium secundum atrial (12.9%), pulmonary valve...
To determine factors associated with poor outcome in children suffering traumatic head injury (HI).A retrospective study over an 8-year period including 454 HI admitted the Intensive Care Unit of a university hospital (Sfax-Tunisia). Basic demographic, clinical, biological and radiological data were recorded on admission during ICU stay. Prognosis was defined according Glasgow scale (GOS) performed after discharge by pediatric physicians.There 313 male (68.9%) 141 female patients. Mean age...
Genetic diseases in the Tunisian population represent a real problem of public health as their spectrum encompasses more than 400 disorders. Their frequency and distribution country have been influenced by demographic, economic social features especially consanguinity. In this article, we report on genetic disease association referred to comorbidity discuss factors influencing expressivity. Seventy-five associations reported among families. This could be individual or familial. 39 comorbid...
Background . Radiation-induced sarcomas are well-known potential late sequelae of radiation therapy. They rare occurrence in jaw bones and even rarer the maxilla. Case report We a case radiation-induced osteosarcoma involving maxilla patient treated with radiotherapy for nasopharyngeal carcinoma 14 years ago. Despite neoadjuvant chemotherapy, surgical treatment could not be performed, received palliative chemotherapy. Conclusions osteosarcomas aggressive often elude early detection timely...
To determine predictive factors of mortality among children after isolated traumatic brain injury.In this retrospective study, we included all consecutive with injury admitted to the 22-bed intensive care unit (ICU) Habib Bourguiba University Hospital (Sfax, Tunisia). Basic demographic, clinical, biochemical, and radiological data were recorded on admission during ICU stay.There 276 patients 196 boys (71%) 80 girls, a mean age 6.7 ± 3.8 years. The main cause trauma was road traffic accident...
Distal renal tubular acidosis (dRTA) is a rare genetic disease caused by mutations in different genes involved the secretion of H+ ions intercalated cells collecting duct. Both autosomal dominant and recessive forms have been described; latter also associated with sensorineural hearing loss.Twenty-two Tunisian families were analyzed for ATP6V1B1 ATP6V0A4 direct sequencing. Dating founder was performed.Two gene found 16/27 dRTA cases. The p.Ile386Hisfs*56 mutation estimated to be older than...