A5100690373- Genetic Mapping and Diversity in Plants and Animals
- Genetic and phenotypic traits in livestock
- Genomics and Phylogenetic Studies
- Genetics, Aging, and Longevity in Model Organisms
- Advances in Cucurbitaceae Research
- Plant Virus Research Studies
- Muscle Physiology and Disorders
- Chromosomal and Genetic Variations
- Cardiomyopathy and Myosin Studies
- Genetics and Plant Breeding
- Genetic diversity and population structure
- Crop Yield and Soil Fertility
- Genetic Associations and Epidemiology
- Dietary Effects on Health
- FOXO transcription factor regulation
- RNA Research and Splicing
- Metabolism, Diabetes, and Cancer
- Virus-based gene therapy research
- Evolution and Genetic Dynamics
- Plant Stress Responses and Tolerance
- Plant and Fungal Species Descriptions
- Animal Genetics and Reproduction
- Liver Disease Diagnosis and Treatment
- Lipid metabolism and disorders
- Protein Kinase Regulation and GTPase Signaling
Zhoukou Normal University
2017-2025
Beijing Academy of Agricultural and Forestry Sciences
2018-2023
State Council of the People's Republic of China
2021
Huazhong Agricultural University
2015-2021
Hainan Medical College Hospital
2015-2018
Nanjing Agricultural University
2014-2016
Zhongda Hospital Southeast University
2014
Abstract Plant height (PH) is a key factor in maize ( Zea mays L.) yield, biomass, and plant architecture. We investigated the PH of diverse inbred lines (117 temperate lines, 135 tropical lines) at four growth stages using unmanned aerial vehicle high-throughput phenotypic platforms (UAV-HTPPs). extracted data an automated pipeline based on crop surface models orthomosaic model. The correlation between UAV manually measured reached 0.95. Under field conditions, grew faster than early...
Cucumber, Cucumis sativus L., is an economically important vegetable crop which processed or consumed fresh worldwide. However, the narrow genetic base in cucumber makes it difficult for constructing high-density maps. The development of massively parallel genotyping methods and next-generation sequencing (NGS) technologies provides excellent opportunity developing single nucleotide polymorphisms (SNPs) linkage map construction QTL analysis horticultural traits. Specific-length amplified...
Salt stress is a major devastating abiotic factor that affects the yield and quality of maize. However, knowledge molecular mechanisms responses to salt in maize limited. To elucidate genetic basis tolerance traits, genome-wide association study was performed on 348 inbred lines under normal conditions using 557 894 single nucleotide polymorphisms (SNPs). The phenotypic data for 27 traits revealed coefficients variation >25%. In total, 149 significant SNPs explaining 6.6%-11.2% each SNP were...
Abstract Goats have achieved global prominence as essential livestock since their initial domestication, primarily owing to remarkable adaptability diverse environmental and production systems. Differential selection pressures influenced by climate led variations in physical attributes, leaving genetic imprints within the genomes of goat breeds raised agroecological settings. In light this, our study pursued a comprehensive analysis, merging data with single nucleotide polymorphism (SNP)...
Dairy goats, a livestock species with long history of milk production, are essential for the economic advancement nations, particularly in regions experiencing growth. In this study, we gathered whole-genome resequencing data 58 including 34 dairy goats and 24 wild (Bezoar), to explore selection signatures linked production traits using ROH (Runs homozygosity), CLR (composite likelihood ratio), Fst (Fixation index), XP-EHH (Ex-tended haplotype homozygosity across populations)...
Differentiation and copy number of repetitive sequences affect directly chromosome structure which contributes to reproductive isolation speciation. Comparative cytogenetic mapping has been verified an efficient tool elucidate the differentiation distribution in genome. In present study, distinct chromosomal structures five Cucumis species were revealed through genomic situ hybridization (GISH) technique comparative major satellite repeats. Chromosome investigated using GISH specific...
Summary Chromosome painting based on fluorescence in situ hybridization ( FISH ) has played an important role chromosome identification and research into rearrangements, diagnosis of abnormalities evolution human animal species. However, it not been applied widely plants due to the large amounts dispersed repetitive sequences chromosomes. In present work, a method for single‐copy gene pools C ucumis sativus was successfully developed. Gene probes with sizes above 2 kb were detected...
The human umbilical cord mesenchymal stem cells (hUCMSCs) have the ability to migrate into tumors and therefore been considered as an alternative source of progenitors for therapy malignant diseases. present study was aimed investigate effect hUCMSCs vehicles a constant transgenic interleukin-21 (IL-21) on ovarian cancer in vivo. were engineered express IL-21 via lentiviral vector- designated 'hUCMSCs-LV-IL-21', then transplanted SKOV3 xenograft-bearing nude mice. therapeutic efficacy...
Ribosomal DNAs are useful cytogenetic markers for chromosome analysis. Studies investigating site numbers and distributions of rDNAs have provided important information elucidating genome organization chromosomal relationships many species by fluorescence in situ hybridization. But relevant studies scarce the genus Cucumis, especially wild species. In present study, FISH was conducted to investigate 45S 5S rDNA among 20 Cucumis accessions, including cultivars accessions. Our results showed...
Southern corn rust (SCR) caused by Puccinia polysora Underw. is a major disease causing severe yield losses during maize production. Here, we identified and mapped the SCR resisitance gene RppM from near-isogenic line Kangxiujing2416 (Jing2416K), which harbors in genetic background of susceptible inbred Jing2416. In this study, inheritance resistance was investigated F2 F3 populations derived cross between Jing2416K The observed 3:1 segregation ratio resistant to plants indicated that...
Genome-wide analyses of maize populations have clarified the genetic basis crop domestication and improvement. However, limited information is available on how breeding improvement reshaped genome in process formation heterotic groups. In this study, we identified a new group (X group) based an examination 512 Chinese inbred lines. The X was clearly distinct from other non-H&L groups, implying that × HIL pattern. We selected core lines for analysis yield-related traits. Almost all traits...
Gut microbiota is involved in the progression of metabolic diseases such as obesity and type 2 diabetes. The ob/ob db/db mice are extensively used models studies on pathogenesis these diseases. goal this study to characterize composition structure gut model at different ages. High-throughput sequencing was obtain sequences highly variable 16S rRNA V3-V4 region from fecal samples. taxa with high abundance both were identified by bioinformatics analysis. Moreover, divergent one ages or same...
// Mingfei Zhu 1, * , Rong Zheng Yiwen Guo 1 Yunxia Zhang 3 and Bo Zuo 2 Key Laboratory of Swine Genetics Breeding Ministry Agriculture & Animal Genetics, Reproduction Education, College Science Technology, Huazhong Agricultural University, Wuhan 430070, P.R. China The Cooperative Innovation Center for Sustainable Pig Production, Life Agronomy, Zhoukou Normal 466000, These authors have contributed equally to this work Correspondence to: Zuo, email: zuobo@mail.hzau.edu.cn Keywords:...
Abstract Plant height is the key factor for plant architecture, biomass and yield in maize ( Zea mays ). In this study, was investigated using unmanned aerial vehicle high-throughput phenotypic platforms (UAV-HTPPs) diversity inbred lines at four important growth stages. Using an automated pipeline, we extracted accurate heights. We found that temperate regions, from sowing to jointing period, rate faster than tropical maize. However, flowering stage, maintained a vigorous state, finally...
Abstract Waxy maize has many excellent characteristics in terms of its nutritional and economic value. In recent decades, the waxy germplasm increased dramatically as a result different selection methods. We collected 200 inbred accessions from origins to study their genetic diversity phylogenetic relationships, identify new mutations. A simple sequence repeat (SSR) analysis revealed wide among accessions. The were clustered into three groups. sequenced gene first 14th exon. Nucleotide...
Peroxisome proliferator-activated receptor delta (PPARD) is a key regulator of lipid metabolism, insulin sensitivity, cell proliferation and differentiation. In this study, we identified two Single Nucleotide Polymorphisms (SNPs, g.1015 A>G g.1018 T>C) constituting four haplotypes (GT, GC, AC AT) in the 5’ regulatory region porcine PPARD gene. Functional analysis showed that transcriptional activity promoter fragment carrying haplotype was significantly lower than other 3T3-L1, C2C12 PK-15...
Recent studies suggested that forkhead box class O3 (FOXO3) functions as a key regulator for the insulin/insulin-like growth factor-1signaling pathway influence aging and longevity. This study aimed to comprehensively elucidate association of common genetic variants in FOXO3 with human longevity Chinese population. Eighteen single-nucleotide polymorphisms (SNPs) were successfully genotyped 616 unrelated long-lived individuals 846 younger controls. No nominally significant effects found....
In this paper, we will discuss if the CETP polymorphism contributes to centenarians in Hainan island. We tested TaqIB and I405V polymorphisms of gene among 276 301 matched healthy individuals by AS-PCR analyzed data with SPSS software package (Version 19.0). Our indicated that allele B1 V have significant differences between control groups P < 0.001. Further analysis implied genotypes B1B1 (P 0.001, OR = 0.148, 95% CI 0.095–0.230) VV 0.001 0.353, 0.237–0.525) were significantly different...
Despite much attention on the history of goat evolution, information origin, demographic history, and expansion route remains controversial. To address these questions, we collected 4,189 published DNA sequences including 1,228 from 57 breeds in China 2,961 193 71 other countries carried out an integrated analysis. We found South had highest genetic diversity lineage B, subclades B2 only were Southwest China, suggesting that B (particularly, subclade B2) probably originated its surrounding...