A5030263923- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Lysosomal Storage Disorders Research
- Palliative Care and End-of-Life Issues
- Economic and Financial Impacts of Cancer
- Health Systems, Economic Evaluations, Quality of Life
- Health Literacy and Information Accessibility
- Cancer survivorship and care
- Skin Protection and Aging
- Acute Myeloid Leukemia Research
- Grief, Bereavement, and Mental Health
- Prostate Cancer Diagnosis and Treatment
- Clinical practice guidelines implementation
- Metabolism and Genetic Disorders
- Prostate Cancer Treatment and Research
- Anatomy and Medical Technology
- Ethics in Clinical Research
- Glycogen Storage Diseases and Myoclonus
- Patient Dignity and Privacy
- Biomedical Research and Pathophysiology
- Genetic factors in colorectal cancer
- BRCA gene mutations in cancer
- Digital Imaging in Medicine
- Sphingolipid Metabolism and Signaling
- Trypanosoma species research and implications
Belfast Health and Social Care Trust
2023
Royal Victoria Hospital
2016-2023
University of Ulster
2016-2023
National Niemann-Pick Disease Foundation
2023
Aston University
2023
Queen's University Belfast
2010-2022
National Cancer Registry
2016-2021
The Northern Ireland Cancer Centre
2010-2018
Linnaeus University
2013
Agder Research
2013
Not recognising a symptom as suspicious is common reason given by cancer patients for delayed help-seeking; but inevitably this retrospective. We therefore investigated associations between recognition of warning signs breast, colorectal and lung anticipated time to help-seeking symptoms each cancer. Computer-assisted telephone interviews were conducted with population-representative sample (N=6965) UK adults age ⩾50 years, using the Awareness Beliefs about Cancer scale. Anticipated...
Objective To investigate the relationship between tumour stage at diagnosis and selected components of primary secondary care in diagnostic interval for breast, colorectal, lung ovarian cancers. Methods Observational study based on data from 6,162 newly diagnosed symptomatic cancer patients Module 4 International Cancer Benchmarking Partnership. We analysed odds advanced as a flexible function length (days first presentation to referral) referral diagnosis), respectively, using logistic...
Objective To investigate the prevalence of physical symptoms that were ‘ever’ and ‘currently’ experienced by survivors prostate cancer at a population level, to assess burden thus inform policy support survivors. Patients Methods The study included 3 348 men surviving for 2–18 years after diagnosis. A cross‐sectional, postal survey 6 559 diagnosed ago with primary, invasive ( ICD 10‐C61) identified via national, population‐based registries in Northern Ireland Republic Ireland. Questions...
Colorectal cancer (CRC) cases are detected late in Malaysia similar to most Asian countries. The Be Cancer Alert Campaign (BCAC) was a culturally adapted mass media campaign designed improve CRC awareness and reduce detection Malaysia. evaluation of the BCAC-CRC aimed assess reach, impact health service use.Participants aged ≥40 years (n = 730) from randomly selected households Selangor State Malaysia, completed interview-based assessments. reach assessed terms responses an questionnaire...
Background: Sun exposure increases risk of skin cancer, especially melanoma, incidence which continues to rise. Reported cancer knowledge and trends in sun care behaviours are documented a UK region where there has been 20 years sun-related health promotion campaigns. Methods: In 2000, 2004 2008, ‘care the sun’ module was included Northern Ireland (NI) Omnibus survey. Randomly selected subjects were asked complete questionnaire proportions respondents analysed by demographic socio-economic...
ABSTRACT Objectives: Most terminally ill cancer patients prefer to die at home, yet only a minority are able achieve this. Our aim was investigate the factors associated with achieving their preference home. Methods: This study took form of mortality followback, population-based, observational survey relatives deceased in Northern Ireland. Individuals who registered death friend or relative (aged ≥ 18 years) between 1 December 2011 and 31 May 2012, where primary cause (ICD10: C00–D48), were...
Background Prostate cancer and its treatment may impact physically, psychologically socially; affecting the health-related quality of life men their partners/spouses. The Life After Cancer Diagnosis (LAPCD) study is a UK-wide patient-reported outcomes which will generate information to improve health well-being with prostate cancer. Methods analysis Postal surveys be sent survivors (18–42 months postdiagnosis) in all 4 UK countries (n=∼70 000). Eligible identified and/or verified through...
Breast and colorectal cancer are the two most common cancers in Malaysia. Low awareness coupled with stigma erroneous beliefs delay help-seeking behaviours, lead to late presentation contribute poor detection rates. Promoting through mass media may be effective improving cancer-related knowledge uptake screening tests. However, research is sparse regarding cultural translation implementation of campaigns Malaysia (and Asia) terms raising about breast cancer. A collaborative partnership...
Objective To establish an international patient-reported outcomes (PROMs) study among prostate cancer survivors, up to 18 years postdiagnosis, in two countries with different healthcare systems and ethical frameworks. Design A cross-sectional, postal survey of survivors sampled recruited via population-based registries. Healthcare professionals (HCPs) evaluated patients for eligibility participate. Questionnaires contained validated instruments assess health-related quality life...
Enabling patients to die in their preferred place is important but achieving of death may increase the informal carer's risk into bereavement.To determine factors family carers bereaved through cancer Northern Ireland.These results form part a larger QUALYCARE-NI study which used postal questionnaires capture quantitative data on bereavement scores using Texas Revised Inventory Grief.Participants were individuals who registered person between 1 December 2011 and 31 May 2012; where (defined...
Objective To evaluate the impact of a mass media campaign in terms improving breast cancer (BC) symptoms awareness and screening uptake. Design Before—and after—study with comparator groups. Setting Selangor State, Malaysia. Participants Malaysian women aged > 40 years (n=676) from randomly selected households. Intervention A culturally adapted (TV, radio, print social media). Primary secondary outcome measures The primary endpoint was BC awareness, which assessed Breast Cancer Awareness...
To provide data on the prevalence of urinary, bowel and sexual dysfunction in Northern Ireland (NI), to act as a baseline for studies prostate cancer outcomes aid service provision within general population.A cross-sectional postal survey 10 000 men aged ≥40 years NI was conducted age-matched distribution living with cancer. The EuroQoL five Dimensions Levels (EQ-5D-5L) 26-item Expanded Prostate Cancer Composite (EPIC-26) instruments were used enable comparisons outcome studies. Whilst...
Abstract Background International Cancer Benchmarking Partnership Module 4 reports the first international comparison of ovarian cancer (OC) diagnosis routes and intervals (symptom onset to treatment start), which may inform previously reported variations in survival stage. Methods Data were collated from 1110 newly diagnosed OC patients aged >40 surveyed between 2013 2015 across five countries (51–272 per jurisdiction), their primary-care physicians (PCPs) specialists, supplement by...
Sunburn and sun bed use increase risk of malignant melanoma, the incidence which continues to rise.To document trends in reported use, sunburn, care knowledge attitudes a U.K. region where there have been 20 years sun-related health promotion campaigns.In 2000, 2004 2008, 'care sun' module was included Northern Ireland (NI) Omnibus survey. Each year 2200 subjects aged 16 over were randomly selected invited complete questionnaire. Proportions respondents analysed by demographic socioeconomic...
Cancer survival in the UK and Denmark are lower when compared with similar countries late diagnosis a possible cause. We aimed to study relationship between barriers attending primary care physician (GP) anticipated time help seeking (ATHS) four cancer symptoms six countries.A population-based survey measuring awareness beliefs conducted within International Benchmarking Partnership Australia, Canada, Denmark, Norway, Sweden UK. Data were collected on perceived GP consultation (including...
Introduction The International Cancer Benchmarking Partnership (ICBP) identified significant international differences in lung cancer survival. Differing levels of comorbid disease across ICBP countries has been suggested as a potential explanation this variation but, to date, no studies have quantified its impact. This study investigated whether comparable, robust comorbidity scores can be derived from the different routine population-based data sets available jurisdictions and, if so, use...
Acid Sphingomyelinase Deficiency (ASMD) is an ultra-rare autosomal recessive lysosomal storage disorder characterized by intracellular lipid accumulation resulting from reduced function of acid sphingomyelinase. Olipudase alfa, enzyme replacement therapy, was recently approved in several countries for the treatment non-neurologic manifestations ASMD. Studies demonstrate improvement organomegaly, pulmonary and profiles with olipudase yet little known about its impact on quality life (QoL)...
The aim of this study was to document cancer trial participation since establishment the Northern Ireland Cancer Trials Network and investigate population disease factors associated with participation. An independent cohort over 51 000 patients from Registry covering same (2007-2012) linked a database 1316 interventional participants in UK region. primary outcome measure an intervention clinical trial. Patients were followed up until 31 March 2013. Kaplan-Meier tests Cox proportional hazard...
Aim To investigate effects on men's health and well-being of higher prostate cancer (PCa) investigation treatment levels in similar populations. Participants PCa survivors Ireland where the Republic (RoI) has a 50% incidence than Northern (NI). Method A cross-sectional postal questionnaire was sent to 2–18 years post-treatment, seeking information about current physical treatment, health-related quality life (HRQoL; EORTC QLQ-C30; EQ-5D-5L) psychological (21 question version Depression,...
Infographics represent a potential means of improving public knowledge about cancer. However, there is little experimental evidence their efficacy. This preliminary study investigates whether infographics are superior to text for the communication information cancer risk in old age via three armed randomized controlled trial. Trial involved allocation concealment and block randomization 30 male participants aged over 50 receive (control) or one two (interventions). Participants who viewed an...