A5079079850- Coccidia and coccidiosis research
- Veterinary medicine and infectious diseases
- Parasitic Infections and Diagnostics
- Synthesis and Biological Evaluation
- Animal Nutrition and Physiology
- Helminth infection and control
- Wheat and Barley Genetics and Pathology
- Pharmacological Effects and Assays
- Yeasts and Rust Fungi Studies
- Polysaccharides and Plant Cell Walls
- Bioactive Compounds and Antitumor Agents
- Wastewater Treatment and Nitrogen Removal
- Pharmaceutical and Antibiotic Environmental Impacts
- Cancer therapeutics and mechanisms
- Plant Disease Resistance and Genetics
- Autophagy in Disease and Therapy
- Antibiotic Resistance in Bacteria
- Epigenetics and DNA Methylation
- Microbial Community Ecology and Physiology
- Insect and Pesticide Research
- Genetic Mapping and Diversity in Plants and Animals
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Peptides and Activities
- Neuropeptides and Animal Physiology
- Synthesis and Reactions of Organic Compounds
Agro-Environmental Protection Institute
2023-2025
Shanghai Veterinary Research Institute
2015-2024
Chinese Academy of Agricultural Sciences
2015-2024
Ministry of Agriculture and Rural Affairs
2018-2024
Shandong University
2024
Shandong University of Technology
2024
Capital Medical University
2020-2024
Nanjing Tech University
2024
Beijing Friendship Hospital
2024
Weatherford College
2024
Abstract:
Abstract Background Japanese encephalitis virus (JEV) has a significant impact on public health. An estimated three billion people in 'at-risk’ regions remain unvaccinated and the number of individuals certain Asian countries is increasing. Consequently, there an urgent need for development novel therapeutic agents against encephalitis. Nitazoxanide (NTZ) thiazolide anti-infective licensed treatment parasitic gastroenteritis. Recently, NTZ been demonstrated to have antiviral properties. In...
To evaluate the antioxidant and immune effects of low molecular yeast β-glucan on mice, three sulfated glucans from Saccharomyces cerevisiae (sGSCs) with different weight (MW) degrees sulfation (DS) were prepared. The structures sGSCs analyzed through high performance liquid chromatography-gel permeation chromatography (HPLC-GPC) Fourier transform infrared spectroscopy (FTIR). sGSC1, sGSC2, sGSC3 had MW 12.9, 16.5 19.2 kDa, respectively, DS 0.16, 0.24 0.27, respectively. In vitro in vivo...
The increasing prevalence of linear anionic surfactants (LAS) presents a significant challenge for biological nitrogen removal in wastewater treatment systems. While heterotrophic nitrification-aerobic denitrification (HN-AD) microflora exhibit high potential, their performance and community dynamics under LAS stress, particularly as function acclimation duration, are not well understood. This study examines the response mechanisms HN-AD to stress following different periods—2 months (SCM) 6...
Deoxyartemisinin, a compound separated from Artemisinin annua L., shows anti-inflammatory and antiulcer activities. 10-Deoxoartemisinin is novel with strong antimalarial effect derivatized artemisinin. Compared to the famous natural artemisinin, deoxyartemisinin lacks peroxide bridge structure, while 10-deoxoartemisinin remains this special group but loses 10-position keto group. To clarify their pharmacological differences, absorption, distribution, metabolism, excretion (ADME) properties...
A rapid, sensitive and specific ultra-high-performance liquid chromatography tandem mass spectrometry (UPLC-MS) method was developed for the analysis of tetracycline antibiotics, including (TC), oxytetracycline (OTC), chlortetracycline (CTC) their 4-epimers (4-epiTCs) in agricultural soil fertilized with swine manure. Soil samples were extracted cleaned-up 10 mL EDTA-McIlvaine buffer solution (pH 4.0), then pre-concentrated using Oasis MAX cartridge eluted 1 by mixing formic acid, methanol...
ABSTRACT The rapid expansion of antibiotic-resistant bacterial diseases is a global burden on public health. It makes sense to repurpose and reposition already-approved medications for use as supplementary agents in synergistic combinations with existing antibiotics. Here, we demonstrate that the anthelmintic drug nitazoxanide (NTZ) synergistically enhances effectiveness lipopeptide antibiotic polymyxin B inhibiting gram-negative bacteria, including those resistant B. Mechanistic...