A5072315589- Concrete and Cement Materials Research
- Intermetallics and Advanced Alloy Properties
- Stress Responses and Cortisol
- Traditional Chinese Medicine Analysis
- Pregnancy and preeclampsia studies
- Advanced materials and composites
- Traditional Chinese Medicine Studies
- MXene and MAX Phase Materials
- Tryptophan and brain disorders
- Innovative concrete reinforcement materials
- Birth, Development, and Health
- Antibiotic Resistance in Bacteria
- Gestational Diabetes Research and Management
- Aluminum Alloys Composites Properties
- Antibiotics Pharmacokinetics and Efficacy
- Maternal and Perinatal Health Interventions
- Epigenetics and DNA Methylation
- Advanced Sensor and Energy Harvesting Materials
- 2D Materials and Applications
- Circadian rhythm and melatonin
- HIV Research and Treatment
- Fire effects on concrete materials
- Neurological Disease Mechanisms and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Pregnancy-related medical research
Yuhuangding Hospital
2016-2024
Qingdao University
2021-2024
Bohai University
2024
Jinan University
2019-2024
Xiangtan University
2023-2024
University of Jinan
2022-2024
Shandong University of Technology
2022
Cangzhou Central Hospital
2016-2021
Central South University
2012-2016
Xiangya Hospital Central South University
2016
Monitoring sweat rate is vital for estimating loss and accurately measuring biomarkers of interest. Although various optical or electrical sensors have been developed to monitor the sensible rate, quantification insensible that directly related body thermoregulation skin barrier functions still remains a challenge. This work introduces superhydrophobic sensor based on polyacrylate sodium/MXene composite sandwiched between two textile layers continuously measure vapor from with high...
Abstract Physical exercise is effective in alleviating mental disorders by improving synaptic transmission; however, the link between body endurance training and neural adaptation has not yet been completely resolved. In this study, authors investigated role of RNA N 6 ‐methyladenosine (m6A), an emerging epigenetic mechanism, improved resilience against chronic restraint stress. A combination molecular, behavioral, vivo recording data demonstrates exercise‐mediated restoration m6A mouse...
Abstract Chronic stress induces anxiety disorders via both neural pathways and circulating factors. Although many studies have elucidated the circuits involved in stress-coping behaviors, origin regulatory mechanism of peripheral cytokines behavioural regulation under conditions are not fully understood. Here, we identified a serum cytokine, lipocalin 2 (LCN2), that was upregulated participants with disorders. Using mouse model chronic restraint (CRS), LCN2 found to be related stress-induced...
Novel β-lactam-β-lactamase inhibitor combinations (BLBLIs) are in clinical development for the treatment of infections caused by carbapenem-resistant and difficult-to-treat resistant (DTR) (defined as resistance to all tested β-lactams fluoroquinolones) Gram-negative bacilli. This study evaluated
Abstract Aerobic exercise effectively relieves anxiety disorders via modulating neurogenesis and neural activity. The molecular mechanism of exercise-mediated anxiolysis, however, remains incomplete. On a chronic restrain stress (CRS) model in adolescent mice, we showed that 14-day treadmill profoundly maintained normal activity axonal myelination the medial prefrontal cortex (mPFC), association with prevention anxiety-like behaviors. Further interrogation mechanisms revealed activation...
Abstract Exercise training can prevent anxiety disorders in both rodent models and human cohorts. The involvement of peripheral factors exercise‐mediated mental health is being appreciated. It recently shown that the hepatic biosynthesis lipocalin‐2 (LCN2) respond to chronic restraint stress (CRS) elicit anxiety‐like behaviors via inhibiting neural activity medial prefrontal cortex (mPFC). Here, it found 14‐day treadmill exercise ameliorates these CRS‐treated mice. Further assays show...
As the most ordinary metabolic disorder during pregnancy, gestational diabetes mellitus (GDM) has become a severe risk for health of both pregnant female and fetus. Astragaloside IV (AS-IV) is dominant active component in Astragalus membranaceus. It been proved that AS-IV anti-inflammation immune-regulation function. We aimed to demonstrate function therapy GDM molecular mechanism this process.C57BL/KsJ-Lepdb/+ mice were used as model. The mRNA levels relative genes research detected by...
What is known and objective Pre-eclampsia one of the most challenging diseases pregnancy. Both nifedipine labetalol have been used for treatment pregnancy-induced severe pre-eclampsia. Methods In present study, efficacy safety oral intravenous pre-eclampsia therapy were compared. Eligible pregnant women with (n = 147) allocated to receive either or labetalol. The primary endpoint study was time needed achieve target blood pressure. Secondary outcomes interval before a new hypertensive crisis...
In this paper, a nickel based superalloy with good corrosion resistance is fabricated by directional solidification, and its microstructure tensile properties were investigated. Microstructure observations reveal that besides the γ′ precipitates γ matrix, some MC, Ni5Hf M3B2 particles precipitate along grain boundary. Tensile tests exhibit alloy has obvious anomalous yield intermediate temperature brittleness (ITB) behaviour. The depend on significantly. Below 650°C, strength decreases...
The heart undergoes physiological hypertrophy during pregnancy in healthy individuals. Metabolic syndrome (MetS) is now prevalent women of child-bearing age and might add risks adverse cardiovascular events pregnancy. present study asks if cardiac remodeling obese individuals with MetS abnormal whether this predisposes them to a higher risk for disorders.
Objective. To observe the clinical efficacy of Bushen Huoxue method combined with platelet-rich plasma (PRP) in treatment knee osteoarthritis (KOA) and its effect on serum joint fluid interleukin-1 (IL-1), interleukin-6 (IL-6), vascular endothelial growth factor (VEGF), prostaglandin E2 (PGE-2). Methods. A total 64 cases KOA diagnosed treated from January 2020 to 2021 were randomly divided into research group control group, 32 each group. The was PRP, took prescription basis assessed...
The glucose intolerance developed during pregnancy is called gestational diabetes mellitus (GDM). GDM has become a severe risk for the health of both mother and baby. Astragaloside IV (AS-IV) dominant active component in Astragalus membranaceus been reported to have anti-inflammation immune-regulation function. We aimed demonstrate function AS-IV therapy molecular mechanism this process. C57BL/KsJ-Lep db/+ female mice were used as model. mRNA levels relative genes research detected by...
This study was designed to clarify the neuroprotective effects of tanshinone IIA (TSA) following cerebral ischemic insult. Adult Sprague–Dawley rats were operated upon achieve a middle artery occlusion cause transient focal ischemia, which then randomly divided into sham-operated control group and ischemia/reperfusion (I/R) groups receiving 2 h occlusion. The treatment received daily intraperitoneal injections high or low doses TSA, for 7 15 days. NeuN immunostaining revealed neuronal loss...
Gestational diabetes mellitus (GDM) is a disease commonly occurs during mid to late pregnancy with pathologies such as hyperglycemia, hyperinsulinemia and mal-development of fetus. We have previously demonstrated that pancreatic endoderm (PE) derived from human embryonic stem cells (hESCs) effectively alleviated diabetic symptoms in mouse model GDM, although the clinical efficacy was limited due oxidative stress. In this study, using anti-oxidant agent naringenin, we aimed further enhance...