- Intracranial Aneurysms: Treatment and Complications
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Ophthalmology and Eye Disorders
- Spinal Fractures and Fixation Techniques
- Sinusitis and nasal conditions
- Vascular Malformations Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Neurofibromatosis and Schwannoma Cases
- Facial Trauma and Fracture Management
- Spine and Intervertebral Disc Pathology
- Cerebrovascular and Carotid Artery Diseases
- Artificial Intelligence in Healthcare and Education
- Cerebrospinal fluid and hydrocephalus
- Veterinary Equine Medical Research
- Asthma and respiratory diseases
- Esophageal Cancer Research and Treatment
University Hospital of Geneva
2018-2024
Ludwig-Maximilians-Universität München
2009-2024
Hôpital de la Timone
2020-2024
University of Geneva
2018-2023
Hôpital Nord
2023
Assistance Publique Hôpitaux de Marseille
2020-2023
Hôpital Beau-Séjour
2018-2021
Geneva College
2018
Institut für Tier-, Natur- und Umweltethik
2010
Institut für Lungenforschung
2009
To evaluate ChatGPT's performance in brain glioma adjuvant therapy decision-making.We randomly selected 10 patients with gliomas discussed at our institution's central nervous system tumour board (CNS TB). Patients' clinical status, surgical outcome, textual imaging information and immuno-pathology results were provided to ChatGPT V.3.5 seven CNS experts. The chatbot was asked give the treatment choice, regimen while considering patient's functional status. experts rated artificial...
Intraoperative electrocorticography (ECoG) captures neural information from the surface of cerebral cortex during surgeries such as resections for intractable epilepsy and tumors. Current clinical ECoG grids come in evenly spaced, millimeter-sized electrodes embedded silicone rubber. Their mechanical rigidity fixed electrode spatial resolution are common shortcomings reported by surgical teams. Here, advances soft neurotechnology leveraged to manufacture conformable subdural, thin-film...
Artificial Intelligence tools are being introduced in almost every field of human life, including medical sciences and education, among scepticism enthusiasm. to assess how a generative language tool (Generative Pretrained Transformer 3.5, ChatGPT) performs at both generating questions answering neurosurgical residents' written exam. Namely, ChatGPT generates questions, it answers human-generated residents answer AI-generated AI its self-generated question. 50 were included the exam, 46...
Abstract BACKGROUND Maximizing extent of resection (EOR) and reducing residual tumor volume (RTV) while preserving neurological functions is the main goal in surgical treatment gliomas. Navigated intraoperative ultrasound (N-ioUS) combining advantages conventional neuronavigation (NN) allows for overcoming limitations latter. OBJECTIVE To evaluate impact real-time NN ioUS preoperative magnetic resonance imaging (MRI) on maximizing EOR glioma surgery compared to standard NN. METHODS We...
ABSTRACT Introduction ChatGPT, a novel AI-based chatbot, sparked lot of interest in the scientific community. Complex central CNS tumour cases require multidisciplinary expert recommendations that incorporate multimodal disease information. Thus, potential ChatGPT to integrate comprehensive treatment information may be tremendous benefit for decision-making. We evaluated glioma management by panel experts. Methods randomly selected 10 patients with primary gliomas discussed at our...
Current prognostic tools in aneurysmal subarachnoid hemorrhage (aSAH) are constrained by being primarily based on patient and disease characteristics admission.To develop validate a complication- treatment-aware outcome prediction tool aSAH.This cohort study included data from an ongoing prospective nationwide multicenter registry all aSAH patients Switzerland (Swiss SOS [Swiss Study aSAH]; 2009-2015). We trained supervised machine learning algorithms to predict binary at discharge (modified...
Background and Purpose—Commonly used tools to determine functional outcome after aneurysmal subarachnoid hemorrhage (aSAH) have limitations. Time spent at the patient’s home has previously been proposed as a robust measure ischemic stroke. Here, we set out validate home-time an aSAH. Methods—We examined prospectively collected data from nationwide multicenter registry of aSAH patients admitted tertiary neurosurgical department in Switzerland (Swiss SOS [Swiss Study on Aneurysmal Subarachnoid...
The objective of this study was to determine patterns care and outcomes in ruptured intracranial aneurysms (IAs) the middle cerebral artery (MCA) a contemporary national cohort.
While prior retrospective studies have suggested that delayed cerebral ischemia (DCI) is a predictor of neuropsychological deficits after aneurysmal subarachnoid hemorrhage (aSAH), all to date shown high risk bias. This study was designed determine the impact DCI on longitudinal outcome aSAH, and importantly, it includes baseline examination aSAH but before onset reduce bias.In prospective, multicenter (8 Swiss centers), 112 consecutive alert patients underwent serial assessments (Montreal...
Each summer, many vacationers enjoy the Mediterranean Sea shores. Among recreational nautical activities, motorboat cruise is a popular choice that leads to significant number of thoracolumbar spine fractures at our clinic. This phenomenon seems be underreported, and its injury mechanism remains unclear. Here, we aim describe fracture pattern propose possible injury. We retrospectively reviewed clinical, radiological, contextual parameters all motorboat-related spinal cases during 14-year...
Abstract BACKGROUND The exact relationship between delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage (aSAH) and neuropsychological impairment remains unknown, as previous studies lacked a baseline examination after aneurysm occlusion but before the DCI-period. Neuropsychological evaluation of acutely ill patients is often applied in busy intensive care unit (ICU), where distraction represents bias to obtained results. OBJECTIVE To evaluate DCI outcome aSAH by...
OBJECTIVE Acute hydrocephalus is a frequent complication after aneurysmal subarachnoid hemorrhage (aSAH). Among patients needing CSF diversion, some cannot be weaned. Little known about the comparative neurological, neuropsychological, and health-related quality-of-life (HRQOL) outcomes in with successful unsuccessful weaning. The authors aimed to assess of by comparing those weaning; latter was defined as occurring permanent diversion at 3 months post-aSAH. METHODS included prospectively...
Intracranial meningiomas are sometimes located anteriorly to the foramen magnum and can cause disabling long tract symptoms. The far-lateral approach has been developed provide an extensive view over bulbopontine junction surrounding lower cranial nerves upper spinal with a good control on vertebral artery, allowing safe resection of such tumors. It is report case anatomical study before after removal meningioma. use allowed us (1) artery in its V3 (Atlantic extradural) V4 (intradural)...
Abstract Introduction CNS cavernomas are a type of raspberry-shaped vascular malformations that typically asymptomatic, but can result in haemorrhage, neurological injury, and seizures. Here, we present rare case brainstem cavernoma was surgically resected whereafter an upbeat nystagmus presented postoperatively. Case report A 42-year old man with sudden-onset nausea, vomiting, vertigo, blurred vision, marked imbalance difficulty swallowing. Neurological evaluation showed bilateral ataxia,...
Full endoscopic resection of solid brain tumors represents a challenge for neurosurgeons. This can be achieved with modern technology and advanced surgical tools.A 23-years-old male was referred to our unit raised intracranial pressure. Head computed tomography magnetic resonance imaging (MRI) revealed obstructive hydrocephalus third ventricle lesion. Endoscopic ventriculostomy biopsy were performed, left frontal external ventricular drain in place. A second-look surgery removal planned....
If endocrine ophthalmopathy progresses despite conservative treatment then indications for surgical decompression are: loss of visual acuity, increasing strabism, and severe keratopathy. Endonasal microsurgery ensures a binocular view onto the intranasal landmarks orbital walls allows simultaneous medial inferior wall as well good relief pressure at apex. Surgical decompressions were performed on 29 orbits in 19 patients, 16 by using endonasal microsurgical, 3 via external approach. The...