- Mycotoxins in Agriculture and Food
- Pesticide Residue Analysis and Safety
- COVID-19 Clinical Research Studies
- Insect and Pesticide Research
- Agricultural safety and regulations
- Long-Term Effects of COVID-19
- Nicotinic Acetylcholine Receptors Study
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune cells in cancer
- Advanced biosensing and bioanalysis techniques
- Airway Management and Intubation Techniques
- Chemokine receptors and signaling
- Microfluidic and Capillary Electrophoresis Applications
- Wheat and Barley Genetics and Pathology
- Nanoparticle-Based Drug Delivery
- Coccidia and coccidiosis research
- Microfluidic and Bio-sensing Technologies
- Chemical Reactions and Isotopes
- Osteoarthritis Treatment and Mechanisms
- Vitamin C and Antioxidants Research
- Inhalation and Respiratory Drug Delivery
- Biosimilars and Bioanalytical Methods
- Veterinary medicine and infectious diseases
- Olfactory and Sensory Function Studies
- Microbial infections and disease research
Hong Kong Polytechnic University
2021-2024
Ghent University
2014-2020
Vrije Universiteit Brussel
1995
A reliable and practical multi-method was developed for the quantification of mycotoxins in plasma, urine, feces pigs, plasma excreta broiler chickens using liquid chromatography–tandem mass spectrometry. The targeted belong to regulated groups, i.e., aflatoxins, ochratoxin Fusarium mycotoxins, two groups emerging Alternaria enniatins. In addition, method transferred a LC-high resolution spectrometry instrument qualitatively determine phase I II metabolites, which analytical standards are...
The aim of this study was to determine the toxicokinetic characteristics ZEN and its modified forms, α-zearalenol (α-ZEL), β-zearalenol (β-ZEL), zearalenone-14-glucoside (ZEN14G), zearalenone-14-sulfate (ZEN14S), including presystemic systemic hydrolysis in pigs. Crossover pig trials were performed by means intravenous oral administration forms. Systemic plasma concentrations administered toxins their metabolites quantified further processed via tailor-made compartmental models. Furthermore,...
Background: The operating room (OR) is a high-risk environment which necessitates preparedness for potential life-threatening incidents, such as fulminant fires. Existing protocols lack specific guidelines anesthesiologists regarding emergency evacuation, and steps to be undertaken when leaving patients under anesthesia. Objectives: This research aimed assess the anesthesiologists’ respond fires in OR propose safe use guideline optimize patients’ chance of survival while minimizing risk...
Applying post-harvest control measures such as adding mycotoxin detoxifying agents is a frequently-used mitigation strategy for mycotoxins. EFSA states that the efficacy of these detoxifiers needs to be tested using specific biomarkers exposure. However, proposed exposure are not further optimized target species. Hence, goal this study was a) evaluate most suitable deoxynivalenol (DON) and zearalenone (ZEN) in porcine plasma, urine feces; DON, aflatoxin B1 (AFB1) ochratoxin A (OTA) plasma...
Dried blood spots (DBSs), a micro-sampling technique whereby drop of is collected on filter paper has multiple advantages over conventional sampling regarding the itself, as well transportation and storage. This first describing development validation method for determination 23 mycotoxins phase I metabolites in DBSs from pigs broiler chickens using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The targeted belong to groups which occurrence feed regulated by European Union,...
Because European maximum guidance values of mycotoxins are only available for feed, mycotoxin exposure in animals is mainly monitored by feed analysis. However, proper sample collection needed to ensure reliable results because uneven distributions and disproportional spread which can hamper the evaluation animals. A cross-sectional study was performed on 40 randomly selected broiler farms Belgium. During a farm visit at animal's age 28 d, pooled beginning end line collected. Feed samples...
<title>Abstract</title> Joint pain is a common post-acute COVID sequelae. Although pathological bone loss has been documented after SARS-CoV-2 infection, little known about the damage to articular cartilage capping ends. Hereby, we characterise temporal changes of bone-cartilage functional unit infection in golden Syrian hamster model. We observed cyst formation at osteochondral junction, chondrocyte senescence and subchondral infected animals 4 30 days post-infection. Endothelin signalling...