A5018055345- Mycotoxins in Agriculture and Food
- Wheat and Barley Genetics and Pathology
- Carcinogens and Genotoxicity Assessment
- Plant Pathogens and Fungal Diseases
- Plant and fungal interactions
- Pesticide Residue Analysis and Safety
- Plant Disease Resistance and Genetics
- Insect and Pesticide Research
- Plant Pathogens and Resistance
- Indoor Air Quality and Microbial Exposure
- Bacillus and Francisella bacterial research
- Genetically Modified Organisms Research
- Health, Environment, Cognitive Aging
- Agricultural safety and regulations
- Radiation Effects and Dosimetry
- Agriculture, Plant Science, Crop Management
- Plant-Microbe Interactions and Immunity
- Veterinary medicine and infectious diseases
- Metabolomics and Mass Spectrometry Studies
- Listeria monocytogenes in Food Safety
- Nutritional Studies and Diet
- Infant Nutrition and Health
- Fungal Plant Pathogen Control
- Plant Toxicity and Pharmacological Properties
- Immune Cell Function and Interaction
Ghent University
2016-2025
Ghent University Hospital
2015-2024
Cancer Research Institute Ghent
2020-2024
TU Wien
2022
University of Vienna
2022
University of Buenos Aires
2022
Weatherford College
2022
Cambridge University Press
2021
ORCID
2021
New York University Press
2021
A total of 174 cereal-based food products, 67 compound feeds and 19 feed raw materials were analysed for the occurrence deoxynivalenol, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, zearalenone, α-zearalenol, β-zearalenol, their respective masked forms, including deoxynivalenol-3-glucoside, zearalenone-4-glucoside, α-zearalenol-4-glucoside, β-zearalenol-4-glucoside zearalenone-4-sulfate. Fibre-enriched bread, bran-enriched cornflakes, popcorn oatmeal collected in Belgian supermarkets from...
Abstract An LC-MS/MS method was developed and validated for the simultaneous determination of deoxynivalenol, zearalenone, T-2-toxin, HT-2-toxin metabolites, including 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, deoxynivalenol-3-glucoside, α-zearalenol, β-zearalenol, zearalenone-4-glucoside, α-zearalenol-4-glucoside, β-zearalenol-4-glucoside zearalenone-4-sulfate in maize, wheat, oats, cornflakes bread. Extraction performed with acetonitrile/water/acetic acid (79/20/1, v/v/v) followed...
Abstract For the first time, a comprehensive human intervention study was conducted to unravel urinary excretion profile and metabolism of fungal metabolite deoxynivalenol (DON) its modified form deoxynivalenol-3-glucoside (DON-3-glucoside). Twenty volunteers were restricted in consuming cereals cereal-based foods for 4 days. At day 3, single bolus 1 µg/kg body weight DON DON-3-glucoside after washing-out period two months administered, 24-h urine collection performed. The analysed DON,...
Fungal contamination and the consequent mycotoxin production is a hindrance to food feed safety, international trade human animal health. In Africa, fungal by Fusarium Aspergillus heightened tropical climatic conditions that create suitable environment for pre- postharvest production. The biocontrol of its associated fusariotoxins has stagnated at laboratory experimental levels with species Trichoderma, Bacillus atoxigenic being tested as most promising candidates. Hitherto, there no impetus...
Aspergillus flavus is the main producer of carcinogenic aflatoxins in agricultural commodities such as maize. This fungus occurs naturally on crops, and produces when environmental conditions are favourable. The aim this study to analyse genetic variability among 109 A. isolates previously recovered from maize sampled a known aflatoxin-hotspot (Eastern region, Kenya) major maize-growing area Rift Valley (Kenya), determine their toxigenic potential. DNA analyses internal transcribed spacer...
In Nigeria, maize, sorghum, and millet are very important cash crops. They consumed on a daily basis in different processed forms diverse cultural backgrounds. These crops prone to fungi infestation, subsequently may be contaminated with mycotoxins. A total of 363 samples comprising maize (136), sorghum (110), (87), ogi (30) were collected from randomly selected markets four agro-ecological zones Nigeria. Samples assessed for Fusarium mycotoxins contamination using multi-mycotoxin liquid...
Mycotoxin contamination in rice can create a health risk for the consumers. In this study, measurement of 23 mycotoxins samples (n = 180) was performed using validated LC–MS/MS method. A food frequency questionnaire used to get consumption data assessment mycotoxin dietary exposure, before calculating adults and children north south regions Pakistani Punjab province. The prevalence aflatoxin B1 (56%), B2 (48%), nivalenol (28%), diacetoxyscirpenol (23%), fumonisin (42%), zearalenone (15%),...
The European Food Consumption Validation (EFCOVAL) project includes 600 men and women from Belgium, the Czech Republic, France, Netherlands, Norway, who had given serum 24-hour urine samples, completed dietary recall (24-HDR) interviews. Consumption, according to 24-HDR, was matched against Safety Authority (EFSA) databases of mycotoxin contaminations, via FoodEx1 standard classifications, producing an indirect external estimate exposure. Direct, internal measurements exposure were made in...
Fungi belonging to Fusarium genera can infect crops in the field and cause subsequent mycotoxin contamination, which leads yield quality losses of agricultural commodities. The zearalenone (ZEN) produced by several species (such as F. graminearum culmorum) is a commonly-detected contaminant foodstuffs, posing tremendous risk food safety. Thus, different strategies have been studied manage toxigenic pathogens contamination. In recent years, biological control fungi emerging an...
The aim of this study was to determine the toxicokinetic characteristics ZEN and its modified forms, α-zearalenol (α-ZEL), β-zearalenol (β-ZEL), zearalenone-14-glucoside (ZEN14G), zearalenone-14-sulfate (ZEN14S), including presystemic systemic hydrolysis in pigs. Crossover pig trials were performed by means intravenous oral administration forms. Systemic plasma concentrations administered toxins their metabolites quantified further processed via tailor-made compartmental models. Furthermore,...
Fermented food samples (