Xiaodong Sun

ORCID: 0000-0002-7062-8931
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Research Areas
  • Magnetic and transport properties of perovskites and related materials
  • Liver Disease Diagnosis and Treatment
  • Shape Memory Alloy Transformations
  • Pancreatic and Hepatic Oncology Research
  • Cancer-related molecular mechanisms research
  • Metabolism, Diabetes, and Cancer
  • Diet, Metabolism, and Disease
  • Thermal Expansion and Ionic Conductivity
  • Medical Imaging Techniques and Applications
  • Redox biology and oxidative stress
  • Pneumonia and Respiratory Infections
  • Bacterial Infections and Vaccines
  • Peripheral Neuropathies and Disorders
  • Radiomics and Machine Learning in Medical Imaging
  • Esophageal Cancer Research and Treatment
  • Abdominal vascular conditions and treatments
  • Fungal Infections and Studies
  • Advanced Thermoelectric Materials and Devices
  • Biopolymer Synthesis and Applications
  • Medicinal Plant Pharmacodynamics Research
  • Soft tissue tumor case studies
  • Axon Guidance and Neuronal Signaling
  • Growth Hormone and Insulin-like Growth Factors
  • Gastrointestinal Tumor Research and Treatment
  • Diabetic Foot Ulcer Assessment and Management

Tibet University
2024

West China Medical Center of Sichuan University
2019-2024

Shanghai Municipal Center For Disease Control Prevention
2024

State Key Laboratory of Surface Physics
2023

Fudan University
2023

First Hospital of Jilin University
2022

Jilin University
2022

Shanghai University
2019-2022

Nankai University
2021

Anyang Tumor Hospital
2020

Abstract Infected diabetic wound (DW) presents a prolonged and challenging healing process within the field of regenerative medicine. The effectiveness conventional drug therapies is hindered by their limited ability to reach deep tissues promote adequate rates. Therefore, there an imperative develop delivery systems that can penetrate while exhibiting multifunctional properties expedite healing. In this study, w e devised soluble microneedle (MN) patch made γ‐PGA, featuring multiple arrays,...

10.1002/adhm.202301985 article EN Advanced Healthcare Materials 2024-05-22

Immune evasion has made ovarian cancer notorious for its refractory features, making the development of immunotherapy highly appealing to treatment. The immune-stimulating cytokine IL-12 exhibits excellent antitumor activities. However, can induce IFN-

10.1016/j.apsb.2023.08.014 article EN cc-by-nc-nd Acta Pharmaceutica Sinica B 2023-08-19

This study aimed to evaluate the seroprevalence of Bordetella pertussis and persistence antibodies following vaccination. We recruited 6060 healthy subjects from five provinces China during 2017–2018. Serum IgG against toxin (anti-PT IgG) filamentous hemagglutinin (anti-FHA IgG), serum IgA IgA) were measured by ELISA. Geometric mean concentration (GMC), seropositivity rate, recent infection rate calculated. Among 0–6 years-olds, anti-PT IgG, IgA, anti-FHA GMCs 6.4 IU/ml (95% CI 6.1–6.8), 2.8...

10.1080/21645515.2024.2417532 article EN cc-by-nc Human Vaccines & Immunotherapeutics 2024-11-15

We aim to investigate the anticancer effects and mechanisms of icaritin against breast cancer.Both estrogen receptor (ER) positive cancer cells MCF- 7 ER-negative MDA-MB-231 were employed. examined on proliferation migration by wound healing assay transwell assay. Cell apoptosis cell cycle MCF-7 analyzed using Flow cytometry. autophagy was assessed western blotting, acridine orange staining confocal microscopy. also detected expression apoptosis-related genes blotting. In addition, an...

10.2174/1566524020666200530212440 article EN Current Molecular Medicine 2020-05-30

Lipid accumulation is the major characteristic of non-alcoholic fatty liver disease, prevalence which continues to rise. We aimed investigate effects and mechanisms icaritin on lipid accumulation.Cells were treated with at 0.7, 2.2, 6.7, or 20 µM for 24 h. The in L02 Huh-7 cells detected by Bodipy oil red O staining, respectively. Mitochondria biogenesis was MitoTracker Orange staining. Glucose uptake adenosine triphosphate content 3T3-L1 adipocytes C2C12 myotubes detected. expression levels...

10.14218/jcth.2021.00050 article EN Journal of Clinical and Translational Hepatology 2021-03-08

Non-alcoholic fatty liver disease (NAFLD) held a high global prevalence in recent decades. Hepatic lipid deposition is the major characteristic of NAFLD. We aim to explore mechanisms psoralen on The effects insulin resistance, deposition, expression and membrane translocation glucose transporter type 4 (GLUT4), autophagy, lipogenesis enzymes were determined sodium oleate-induced L02 cells. Chloroquine 3-MA employed. AMP-activated protein kinase alpha (AMPKα) was knocked down by siRNA....

10.3390/cells11071067 article EN cc-by Cells 2022-03-22

Objective To evaluate a modified totally laparoscopic splenectomy plus pericardial devascularization (LSPD) for the treatment of portal hypertension.Methods We applied technique ligating splenic artery in advance followed by establishment tunnel underneath hilum and consecutive transection secondary pedicles gastric coronary vein with Endo-GIA during process splenectomy.Results Totally procedures were performed successfully 28 cases.Procedure was converted to open surgery one case because...

10.3760/cma.j.issn.1007-631x.2014.03.002 article EN Zhonghua putong waike zazhi 2014-03-25

Objective To discuss the surgical treatment of intraductal papillary mucinous neoplasms pancreas (IPMN). Methods The clinical data 42 IPMN cases undergoing in our hospital during past 4 years were analyzed retrospectively. Results Routine CT or MRI examination was made cases, ERCP 6 ultrasonic endoscopy 12 fine needle biopsy by endoscopic ultrasonography cases. There main duct IPMN, 24 branch mixed IPMN. Pancreatoduodenectomy performed cases; underuent laparoscopic central...

10.3760/cma.j.issn.1007-631x.2017.06.001 article EN Zhonghua putong waike zazhi 2017-06-25

Objective To analyze setup errors and guide the calculation of margins from clinical target volume (CTV) planning (PTV) in esophageal cancer patients treated with tomotherapy by MVCT image-guided system. Methods Sixty-four our hospital 2016 were randomly selected. images acquired after patients’ positioning co-registered KVCT images. The x, y, z translations roll rotation analyzed t-test or one-way ANOVA. Meanwhile, PTV margin was calculated based on formula M= 2.5∑+...

10.3760/cma.j.issn.1004-4221.2017.04.013 article EN Zhonghua fangshe zhongliuxue zazhi 2017-04-15

Objective To explore the application of ArcCheck system in validation Helical and Direct tomotherapy plans for esophageal cancer summarize relevant experience. Methods The verification were established 32 patients with at different positions according to doctor′s instructions, which verified by ArcCHECK compare passing rate results.The correlation between volume target area planned was analyzed. The therapeutic plan a small made. placed center phantom detectors statistically...

10.3760/cma.j.cn113030-20181221-00005 article EN Zhonghua fangshe zhongliuxue zazhi 2020-04-15
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