A5083770155- Lung Cancer Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Pleural and Pulmonary Diseases
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Pectus Deformity Diagnosis and Treatment
- RNA modifications and cancer
- Spectroscopy and Chemometric Analyses
- Cancer Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Head and Neck Cancer Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Tracheal and airway disorders
- Innovative Energy Harvesting Technologies
- Kruppel-like factors research
- Cancer Research and Treatments
- Wireless Power Transfer Systems
- Water-Energy-Food Nexus Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Speech and Audio Processing
- Innovative Human-Technology Interaction
- PARP inhibition in cancer therapy
- Digital Media Forensic Detection
- Cancer-related molecular mechanisms research
- Protein Degradation and Inhibitors
China Medical University
2017-2025
Liaoning Cancer Hospital & Institute
2017-2025
Dalian University of Technology
2021-2024
Civil Aviation University of China
2023
Dalian Institute of Chemical Physics
2023
Chinese Academy of Sciences
2023
Central China Normal University
2022
Beijing Jiaotong University
2021
North China University of Technology
2020
Background: Long non-coding RNAs (lncRNAs) have been reported to participate in many diseases including non-small cell lung cancer (NSCLC), thus our objective was investigate the impact of lncRNA SBF2-AS1 modulating microRNA-302a (miR-302a) expression on radiosensitivity NSCLC.Methods: The SBF2-AS1, miR-302a and muscleblind-like 3 (MBNL3) NSCLC tissues radiotherapy-sensitive radiotherapy-resistant groups tested. parent resistant strains (NCI-H1299 NCI-H1299R cells) detected. Further, cells...
Abstract Immunotherapy has become a prominent first-line cancer treatment strategy. In non-small cell lung (NSCLC), the expression of PD-L1 induces an immuno-suppressive effect to protect cells from immune elimination, which designates as important target for immunotherapy. However, little is known about regulation mechanism and function in cancer. this study, we have discovered that KEAP1 serves E3 ligase promote ubiquitination degradation. We found overexpression suppressed tumor growth...
Background:The role of Rac3 in cell proliferation lung adenocarcinoma has been tackled our previous study.However, the invasion and migration is still not clear.Methods: The expression specimens paired noncancerous normal tissues were evaluated by immunohistochemistry. Lentivirus-mediated RNA interference (RNAi) was employed to silence lines A549 H1299.A p38 MAPK inhibitor (LY2228820) inhibit activity pathway.Cell vitro examined assays, respectively.PathScan ® intracellular signaling array...
Background Checkpoint targets play a key role in tumor-mediated immune escape and therefore are critical for cancer immunotherapy. Unfortunately, there is lack of bioinformatics resource that compile all the checkpoint translational research drug discovery immuno-oncology. Methods To this end, we developed therapeutic target database (CKTTD), first comprehensive (proteins, miRNAs LncRNAs) their modulators. A scoring system was adopted to filter more relevant with high confidence. In...
Introduction The aim of this study was to assess the prognoses patients with non‐small cell lung cancer (NSCLC) according current nodal (N) categories tumor, node and metastasis (TNM) classification number involved lymph stations. Methods Five hundred seventy NSCLC underwent surgery from 1 January 2005 31 December 2009 were analysed retrospectively. Postoperative overall survival two classifications: N0, N1, N2 N3 those based on stations: N1a (single N1), N1b (multiple N2a1 without N2a2 N2b1...
Radical surgery including mediastinal lymph node dissection is the standard treatment for early-stage non-small cell lung cancer (NSCLC). About 50% nodules are pure ground glass or part-solid nodules, which predominantly clinical stage IA NSCLC. Non-solid rarely develop metastasis.A phase III study was started in China to evaluate non-inferiority overall survival of spared compared with A total 1362 patients will be enrolled from 4 institutions 2-3 years. The second endpoints relapse-free...
Evaluate the effect of enhanced recovery after surgery (ERAS) protocol on postoperative quality pectus excavatum patients with Nuss procedure.A retrospective study was performed undergoing procedure from Department Thoracic Surgery The Cancer Hospital China Medical University between September 2016 and 2019. Patients were divided into 2 groups by perioperative management: traditional group (T group) ERAS strategy (E group). outcome measures drainage time, hospital complications measured...
It is unclear whether hybrid video-assisted thoracoscopic surgery (VATS) sleeve lobectomy (SL) could be an alternative to thoracotomy SL for non-small cell lung cancer (NSCLC) treatment. The aim of the study investigate safety and efficacy VATS SL.We collected 112 patients who received or primary treatment NSCLC at Liaoning Cancer Hospital & Institute from November 2016 September 2021. Perioperative survival data were collected, retrospective analysis was conducted on 91 21 evaluate two...
The aim of this study was to compare thoracoscopic surgery for spontaneous pneumothorax under epidural and/or local anesthesia (ELA) with that general and prove the feasibility safety ELA pneumothorax. Relevant studies were searched in five databases from their date publication June 2016. We collected analyzed data concerning operative time, hospital stay, complications, air leak, recurrence perioperative mortality. A forest plot performed differences between two groups. There no significant...
Sleeve lobectomy (SL) and extended SL (ESL), which aim to preserve pulmonary function enhance the quality of life patients while ensuring oncological outcomes, are valuable surgical options for treatment centrally located non-small cell lung cancer (NSCLC). This study aimed compare perioperative adverse events long-term survival between ESL in NSCLC patients, providing a comprehensive review complications, assess roles thoracic oncology.
This paper focuses on the application environment of solar charging in Energy Harvesting Wireless Sensor Networks (EH-WSN), and studies how to effectively use energy prediction extend life sensor networks. Considering algorithm standard Least Mean Square (LMS), output power error is large when weather changes are fluctuating, collection cannot be accurately predicted. proposes a Correlation (C-LMS) model that introduces correlation factor changes. The has low complexity with certain...
Abstract Immunotherapy has become a prominent first-line cancer treatment strategy. In non-small cell lung (NSCLC), the expression of PD-L1 induces an immuno-suppressive effect to protect cells from immune elimination, which designates as important target for immunotherapy. However, little is known about regulation mechanism and function in cancer. this study, we have discovered that KEAP1 serves E3 ligase promote ubiquitination degradation. We found overexpression suppressed tumor growth...
A 60-year-old woman was admitted to our department for a left upper lobe and lower ground glass nodules. Three-dimensional computed tomography bronchography angiography showed an aberrant anterior ascending segmental pulmonary artery (A3aii) branching from the lingular artery. We performed division segmentectomy superior opacity lesions, A3aii variation safely dissected. The patient received uneventful recovery, final pathologic diagnosis early-stage multiple primary lung cancers. of...
Abstract: Pectus excavatum is the most common chest wall deformity, and some patients also have it combined with cardiac arrhythmias. It a rare occurrence for there to be severe conduction block that requires temporary pacemaker implantation before surgical correction. Here we reported case of pectus second-degree atrial-ventricular (AV) (Mobitz II) who had Nuss procedure. The young patient deformity 6 years got worse age. Haller index was 4.21, evaluated he should receive An AV found during...
Extending the literature in path dependence we study role that prior domestic M&A experience plays firms first cross-border M&A. Using 333 listed Chinese use organizational learning to explain what firm and market characteristics may impact dependencies related chosen ownership level for newly acquired firm. We find performance, management stability, international experience, target-to-target similarity, culture likelihood of having a similar structure from its activities Implications...
To solve the problem that speech information hiding algorithm based on random position selection and matrix coding has insufficient capacity, paper proposes a novel pitch modulation steganography method inactive frame. In this method, least significant bit (LSB) replacement is adopted for frames, active which realises frames. Finally, simulation experiments are carried out The results indicate maximum capacity of in can reach 241.67 bps, significantly improves at same time concealment also...
Objective To analyze the Nuss procedure results, risk factors responsible for postoperative complications and management of complications. Methods We restrospectively reviewed clinical data pectus excavatum (PE) patients undergoing from September 2009 to April 2016.There were 68 boys 7 girls, 59 children 16 adult patients, 66 with one bar 9 two bars implanted. Results Seventy-five recruited all operations completed successfully.In 30 removed successfully during a median...