Nutritional status influences the growth and development of eyes. However, there are few studies on association between diet, especially whole grains (WG) consumption, myopia. The study aimed to evaluate WG intake myopia prevalence among primary school-age children in China.This cross-sectional epidemiological conducted November 2019 December included 586 children, aged 6-12 years, attending school Binhai district, Tianjin, China. Ophthalmologic examinations optometric cycloplegic refraction...

Purpose To predict the need for cycloplegic assessment, as well refractive state under cycloplegia, based on non-cycloplegic ocular parameters in school-age children. Design Random cluster sampling. Methods The cross-sectional study was conducted from December 2018 to January 2019. sampling used select 2,467 students aged 6–18 years. All participants were primary school, middle school and high school. Visual acuity, optical biometry, intraocular pressure, accommodation lag, gaze deviation...

To determine the prevalence of vision impairment (VI) and refractive error in first year university students at Tianjin Medical University.This is a cross-sectional observational cohort study VI among University. The were involved this given detailed questionnaire including age, birth date, spectacle wearing history. A standardized ophthalmologic examination visual acuity (VA), slit-lamp examination, non-cycloplegic auto-refraction, objective refraction, fundus photography, their spectacles...

Myopia is a prevalent eye disorder, especially among children and adolescents in eastern Asian countries. Multiple measures have already been taken to prevent treat myopia, including atropine dopamine. However, the serum metabolic picture of myopia has not yet studied as whole remains largely unclear. In this paper, prospective panoramic study was carried out find metabolomic lipidomic myopia. With untargeted mass spectrometry (MS), 211 studied. The MS features were first grouped across...

Abstract Background To investigate the new cornea biomechanical parameter stress-strain index (SSI) in Chinese healthy people and factors associated with SSI. Methods A total of 175 eyes from participants were included this study. Axial length was measured Lenstar LS-900. Pentacam curvature anterior chamber volume (ACV). Cornea properties assessments performed by corneal visualization Scheimpflug technology (Corvis ST). Student’s t-test, one-way ANOVA, partial least square linear regression...

Purpose Refractive errors, particularly myopia, constitute a significant global public health concern, contributing to morbidity and disability. A more comprehensive understanding of the determinants refractive errors differences between urban rural areas is essential develop effective preventive measures for youth. This study aimed compare prevalence risk factors among youth in Tianjin, China. Methods school-based cross-sectional was conducted 2022. Elementary, middle, high school students...

To evaluate the effectiveness of Grand Seiko Ref/Keratometer WAM-5500 compared to Topcon KR800 autorefractor in detecting refractive error large scale vision screening for Chinese school age children with WHO criteria.A total 886 participants were enrolled mean 9.49±1.88y from Tianjin, China. Spherical equivalent (SE) was obtained un-cycloplegic autorefraction and cycloplegic autorefraction. KR 800 (Topcon) (WAM) autorefractors used. Bland-Altman Plot regression generated compare their...

Human epidermal growth factor receptor 2 (HER2)-targeted agents have significantly improved the outcomes of patients with HER2-positive breast cancer; however, a large proportion still develop resistance to trastuzumab. In this study, we investigated efficacy and safety inetetamab, another anti-HER2 antibody, combined pyrotinib oral vinorelbine in advanced cancer so as provide new ideas for treatment.

To analyze the potential mechanisms of growth differences in spotted seabass (Lateolabrax maculatus) fed a low-phosphorus diet, total 150 with an initial body weight 4.49 ± 0.01 g were used (50 fish per tank) and diet for eight weeks. At end experiment, five heaviest lightest selected from each tank as fast-growing (FG) slow-growing (SG), respectively, their livers analyzed by metabolomics transcriptomics. The hepatic antioxidant capacity FG was significantly higher than that SG. A 431...

Tyrosine kinase inhibitors (TKIs) are effective for treating human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer. However, therapies subsequent to TKI progression remain controversial, and treatments resistance urgently needed. We evaluate the practice of exchange TKIs, which involves treatment with a different following prior failure. Specifically, this study investigated efficacy pyrotinib-based therapy in lapatinib-resistant HER2-positive cancer...

AIM: To evaluate related factors with the change of spherical equivalents (ΔSE) and determine suitable predictor clinically significant ΔSE (≥0.50 D) cyclopentolate hydrochloride on Chinese children. METHODS: A total 145 right eyes children aged 4 to 15y were enrolled. Intraocular pressure, axial length lag accommodation (LOA) assessed before cycloplegia induced by 3 drops 1% at 5-minute intervals. SE was measured 1h after first drop cyclopentolate. compared between different gender groups...

Rationale: An accessory ovary is a rare structure containing normal ovarian tissue, which has direct or ligamentous connection with and eutopic ovary. Patient concerns: In the study, we reported 46-year-old woman presented secondary amenorrhea virilization symptoms for 1 year. Diagnoses: Endocrine evaluation revealed slightly elevated serum cortisol, extremely 24-hour urinary-free cortisol testosterone. Clinical assessment exhibited large solid mass heterogeneous enhancement in left...

Adrenocorticotropic hormone (ACTH)-independent Cushing's syndrome (CS) is mostly due to unilateral tumors, with bilateral tumors rarely reported. Its common causes include primary pigmented nodular adrenocortical disease, ACTH-independent macronodular adrenal hyperplasia, and adenomas (BAAs) or carcinomas. BAAs causing CS are rare; up now, fewer than 40 BAA cases have been The accurate diagnosis evaluation of critical for determining optimal treatment options. Adrenal vein sampling (AVS) a...

Abstract Background The increase in the prevalence of myopia has become a matter serious public health concern, and few studies to date have examined ocular biometric parameters young Chinese adults. This study aimed investigate longitudinal refractive development first-year university students influence near work. Methods included 526 from Tianjin Medical University (mean age, 18.34 years; 313 females 213 males). From 2016 2018, participants underwent biometry measurements subjective...

Purpose: To map the time course of changes in intraocular straylight human eye 1 year after initial lens wearing for orthokeratology treatment using objective double-pass technique.Materials and Methods: A total 35 subjects (19 males 16 females) completed study. The mean age was 11.46 ± 2.33 years (range, 8–16 years). All were fitted with spherical four-zone lenses following procedures recommended by manufacturer. required to wear at least eight consecutive hours night. After removal during...

Purpose: To investigate the progression rates of axial length (AXL) among school-age children with baseline astigmatism and spherical ametropia. Methods: Annual vision screenings were conducted at seven schools in Tianjin, China, from 2018 to 2022. Ocular biometry non-cycloplegic autorefraction collected. Children 5 16 years old without any myopia interventions included categorized by their magnitude (control, low, or high) axis orientation (with rule [WTR], against [ATR], oblique)....

Background: Palbociclib has been approved for marketing in China. However, its effectiveness, safety, and latent variables the Chinese population require further investigation. Methods: Information was retrieved from 397 patients with metastatic breast cancer (mBC) who received at least two cycles of palbociclib plus endocrine therapy (PAL ET) eight clinical sites The patients’ demographic characteristics, treatment patterns, adverse events (AEs) were analyzed. Results: objective response...

To improve the differential diagnosis of sellar region mass, 4 cases with mass and misdiagnosed as lymphocytic hypophysitis (LYH) were reviewed retrospectively.The patients (2 male 2 female) aged 20-60 years old all presented symptoms headache, polydipsia polyuria.Biochemical studies confirmed diagnoses central diabetes insipidus hypopituitarism.Head MRI scans showed LYH like image for cases, and, thus, high dose methylprednisolone pulse therapy (HDMPT) was applied to patients.Their...

Objective To evaluate and compare corneal sensitivity after Femtosecond LASIK (FS-LASIK) small incision lenticule extraction (SMILE) from a systematic review of literature.Methods This was meta-analysis study.A literature retrieval conducted in Medline,the Cochrane Library,CBM disc,and CNKI.Central FS-LASIK SMILE compared by meta-analysis,including pre-operation,1 week,1 month,3 months 6 post-operation.A statistical analysis performed using RevMan 5.0 software.Weighted mean difference (WMD)...