A5005705058- Antimicrobial Resistance in Staphylococcus
- Brucella: diagnosis, epidemiology, treatment
- Helminth infection and control
- Plant Pathogens and Fungal Diseases
- Vasculitis and related conditions
- Polysaccharides Composition and Applications
- Plant Disease Resistance and Genetics
- Coccidia and coccidiosis research
- Parasite Biology and Host Interactions
- Milk Quality and Mastitis in Dairy Cows
- Bacterial biofilms and quorum sensing
- Urticaria and Related Conditions
- Biochemical and Structural Characterization
- Animal Disease Management and Epidemiology
- Fermentation and Sensory Analysis
- Anesthesia and Pain Management
- Microbial infections and disease research
- Monoclonal and Polyclonal Antibodies Research
- Probiotics and Fermented Foods
- Inflammasome and immune disorders
- Herpesvirus Infections and Treatments
- Animal Diversity and Health Studies
- Mycobacterium research and diagnosis
- Nausea and vomiting management
- vaccines and immunoinformatics approaches
Consejo Nacional de Investigaciones Científicas y Técnicas
2012-2024
National University of Comahue
2020-2024
Garrahan Hospital
2024
Centro Científico Tecnológico - Tucumán
2015-2023
Centro Científico Tecnológico - Tandil
2014-2021
National University of General San Martín
2021
Pontificia Universidad Católica del Ecuador
2020
National University of Río Cuarto
2019
Servicio Gallego de Salud
2019
University of Buenos Aires
2005-2018
Intrinsically disordered proteins, defying the traditional protein structure-function paradigm, are a challenge to study experimentally. Because large part of our knowledge rests on computational predictions, it is crucial that their accuracy high. The Critical Assessment Intrinsic Disorder prediction (CAID) experiment was established as community-based blind test determine state art in intrinsically regions and subset residues involved binding. A total 43 methods were evaluated dataset 646...
Selection pressures exerted on Staphylococcus aureus by host factors may lead to the emergence of mutants better adapted evolving conditions at infection site. This study was aimed identifying changes that occur in S. exposed defense mechanisms during chronic osteomyelitis and evaluating whether these affect virulence organism. Genome assessment two isolates collected 13 months apart (HU-85a HU-85c) from a with made full genome sequencing. Agr functionality assessed qRT-PCR. Isolates were...
Alvarez, Lucia H.M.D.; Fajardo, Ramón V.M.D.; Lopez, Elvia M.M.D.; Pedroza, Rina R.M.V.Z.; Hemachudha, Thirawat M.D.; Kamolvarin, N. Ph.D.; Cortes, Gilberto C.M.V.Z.; Baer, George M. D.V.M., M.P.H. Author Information
Staphylococcus aureus capsular polysaccharides (CP) have been shown to enhance staphylococcal virulence in numerous animal models of infection. Although serotype 5 CP (CP5) and CP8 predominate among S. isolates from humans, most bovines with mastitis Argentina are capsule negative. This study was designed evaluate the effects CP5 expression on pathogenesis experimental murine mastitis. Lactating mice were challenged by intramammary route one three isogenic strains producing CP5, CP8, or no...
ABSTRACT Staphylococcus aureus is the bacterium most frequently isolated from milk of bovines with mastitis. Four allelic groups, which interfere regulatory activities among different have been identified in accessory gene regulator ( agr ) system. The aim this study was to ascertain prevalence groups capsulated and noncapsulated S. bacteria mastitic Argentina whether a given group associated MAC-T cell invasion vivo persistence. Eighty-eight percent bovine strains were classified I....
ABSTRACT The pathogenesis of Staphylococcus aureus infections is influenced by multiple virulence factors that are expressed under variable conditions, and this has complicated the design an effective vaccine. Clinical trials targeted capsule or clumping factor A (ClfA) failed to protect recipients against staphylococcal infections. We passively immunized lactating mice with rabbit antibodies S. capsular polysaccharide (CP) serotype 5 (CP5) CP8 monoclonal ClfA. Mice CP5 ClfA had...
Capsular polysaccharides (CP) of serotypes 5 (CP5) and 8 (CP8) are major Staphylococcus aureus virulence factors. Previous studies have shown that salicylic acid (SAL), the main aspirin metabolite, affects expression certain bacterial In present study, we found S. strain Reynolds cultured with SAL was internalized by MAC-T cells in larger numbers than organisms not exposed to SAL. Furthermore, internalization isogenic nonencapsulated into significantly affected preexposure Pretreatment...
To clinically characterize a group of thrombocytopenic dogs that received cryopreserved platelet concentrate (cPC) transfusion, assess efficacy cPC treatment in improving patient outcome, and compare treated to control population did not receive transfusions.Retrospective study.University teaching hospital.Eighty-six client-owned (43 group, 43 group).None.Medical records transfusions those (control population) from January 2007 through March 2013 were reviewed. Dogs receiving statistically...
To assess the comparative drug systemic exposure of a reference (RF) and four test (Test I, Test II, III IV) formulations triclabendazole (TCBZ) in heifers.Thirty Holstein heifers were randomly distributed into five groups (n=6 per group). Animals RF group received formulation (Fasinex), those other different commercially available TCBZ IV). All treatments orally administered at 12 mg/kg bodyweight. The concentrations metabolites plasma between 0 168 hours after treatment quantified by...
Aureobasidium pullulans is a yeast-like fungus with remarkable phenotypic plasticity widely studied for its importance the pharmaceutical and food industries. So far, genomic studies strains from all over world suggest they constitute genetically unstructured population, no association by habitat. However, mechanisms which this genome supports so many permutations are still poorly understood. Recent works have shown of sequencing yeast genomes extreme environments to increase repertoire...
1. To optimise the use of albendazole (ABZ) as an anthelmintic in hens, effects fasting and type diet on plasma kinetics ABZ its metabolites were evaluated. 2. Twenty-four hens distributed into 4 groups: In experiment I Fed group fed ad libitum, while Fasted was fasted over a 12-h period. II Pelleted with pelleted commercial food, Grain cereal grains. All groups treated by oral route. Blood samples taken analysed HPLC. 3. albendazole-sulphoxide (ABZSO) albendazole-sulphone (ABZSO2) recovered...