Guanzhi Ye

ORCID: 0000-0002-7279-2567
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer-related molecular mechanisms research
  • Radiomics and Machine Learning in Medical Imaging
  • Gastric Cancer Management and Outcomes
  • Esophageal Cancer Research and Treatment
  • Lung Cancer Research Studies
  • Cardiac tumors and thrombi
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • RNA modifications and cancer
  • Lymphoma Diagnosis and Treatment
  • Head and Neck Cancer Studies
  • Ferroptosis and cancer prognosis
  • Genomics, phytochemicals, and oxidative stress
  • Phagocytosis and Immune Regulation
  • Cancer, Hypoxia, and Metabolism
  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers
  • Viral-associated cancers and disorders

First Affiliated Hospital of Xiamen University
2022-2025

Zhongshan Hospital
2019-2020

Fudan University
2019-2020

Sun Yat-sen University
2019-2020

The First Affiliated Hospital, Sun Yat-sen University
2019-2020

The optimal time interval from neoadjuvant immunotherapy combined with chemotherapy to surgery for esophageal squamous cell carcinoma remains unknown. This research aims assess the impact of on pathological response and survival prognosis. Esophageal patients receiving followed by esophagectomy between January 2021 March 2024 were included. response, outcomes, surgical postoperative complications compared timely group (time ≤ 6 weeks) delayed > weeks). A total 133 cases included in this...

10.1186/s12876-025-03802-5 article EN cc-by-nc-nd BMC Gastroenterology 2025-04-04

Abstract Primary pulmonary mucosa‐associated lymphoid tissue‐derived (MALT) lymphoma is a rare disease with favorable prognosis. However, its clinical characteristics, diagnosis, treatment, and prognoses remain unclear. We retrospectively analyzed 80 patients pathologically confirmed MALT from 2006 to 2018. The treatments, of all the were recorded. Patients stratified into surgery biopsy groups, respectively, evaluate role in diagnosis treatment lymphoma. compared between different...

10.1002/cam4.2683 article EN cc-by Cancer Medicine 2019-11-05

Abstract Forkhead box protein 1 (FOXP1) serves as a tumour promoter or suppressor depending on different cancers, but its effect in oesophageal squamous cell carcinoma has not been fully elucidated. This study investigated the role of FOXP1 through bioinformatics analysis and experimental verification. We determined public databases that expresses low compared with normal tissues, while high expression indicates better prognosis. identified potential target genes regulated by FOXP1, explored...

10.1111/jcmm.18294 article EN cc-by Journal of Cellular and Molecular Medicine 2024-04-01

This research aimed to identify risk factors of pulmonary metastasis (PM) from hepatocellular carcinoma (HCC) and prognostic patients with PM HCC at initial diagnosis.Patients diagnosed between 2010 2015 were reviewed retrospectively in the Surveillance, Epidemiology, End Results (SEER) database. Patients diagnosis identified entire cohort. Predictors for by multivariate logistic regression analysis. Independent determined univariate Cox Nomograms also constructed quantifying overall...

10.7717/peerj.7496 article EN cc-by PeerJ 2019-08-16

Lung cancers arising in never smokers have been suggested to be substantially different from lung at an epidemiological, genetic and molecular level. Focusing on non-small cell cancer (NSCLC), we characterized patients China looking for demographic clinical differences between the smoking never-smoking subgroups.In total, 891 with NSCLC, including 841 adenocarcinoma 50 squamous carcinoma, were recruited this study. Association of status features NSCLC was determined, risk factors lymph node...

10.1186/s12931-022-02199-z article EN cc-by Respiratory Research 2022-10-29

We aimed to evaluate the efficacy of log odds positive lymph nodes (LODDS) in survival prediction patients with esophageal carcinoma receiving neoadjuvant therapy, compared N descriptor and node ratio (LNR).Patients therapy from 2004 2015 were reviewed Surveillance, Epidemiology, End Results database. The receiver operating characteristics curve area under (AUC) used compare discriminatory power among descriptor, LNR, LODDS. goodness fit was measured using -2 log-likelihood (-2LLR).About...

10.1002/jso.25888 article EN Journal of Surgical Oncology 2020-03-05

Tumor cells tend to utilize glycolysis rather than aerobic respiration even under conditions. OVOL2, an inhibitory C2H2 zinc finger transcription factor, is a potential tumor suppressor in cancers. However, the association between OVOL2 and energy metabolism unknown.Western blotting was used determine expression of different non-small cell lung cancer (NSCLC) lines mouse models. The metabolic parameters NSCLC following overexpression or knockdown were examined. To define mechanism by which...

10.1186/s12964-022-00845-z article EN cc-by Cell Communication and Signaling 2022-03-28

This research aimed to clarify the metastatic patterns of subcarinal, right and left recurrent laryngeal nerve lymph nodes in thoracic esophageal squamous cell carcinoma investigate appropriate strategies for node dissection.

10.1007/s00432-024-05911-2 article EN cc-by-nc-nd Journal of Cancer Research and Clinical Oncology 2024-08-07
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