A5067708318- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Traumatic Brain Injury and Neurovascular Disturbances
- Peripheral Artery Disease Management
- Vascular Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Congenital Heart Disease Studies
- Cerebrospinal fluid and hydrocephalus
- Coronary Interventions and Diagnostics
- Cardiac Structural Anomalies and Repair
- Tracheal and airway disorders
- Cardiac Valve Diseases and Treatments
- Moyamoya disease diagnosis and treatment
- Central Venous Catheters and Hemodialysis
- Venous Thromboembolism Diagnosis and Management
- Cell Adhesion Molecules Research
- Renal and Vascular Pathologies
- Brain Metastases and Treatment
- Cardiovascular and exercise physiology
- Cardiac tumors and thrombi
- Sarcoma Diagnosis and Treatment
University of Massachusetts Chan Medical School
2020-2024
University Hospital of Zurich
2019-2023
University of Zurich
2019-2023
UMass Memorial Health Care
2021
Evangelismos Hospital
2010-2015
GATA Haydarpaşa Eğitim Hastanesi
2015
Istanbul University-Cerrahpaşa
2015
Üsküdar University
2015
Istanbul University
2015
Agios Pavlos General Hospital
2010-2011
Delayed ischemic neurological deficit (DIND) is a major driver of adverse outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH), defining an unmet need for therapeutic development. Cell-free hemoglobin that released from erythrocytes into the cerebrospinal fluid (CSF) suggested to cause vasoconstriction and neuronal toxicity, correlates occurrence DIND. CSF aSAH disrupted dilatory NO signaling ex vivo cerebral arteries, which shifted vascular tone balance dilation constriction....
Endovascular interventions are increasingly becoming the preferred approach for treating strokes and cerebral artery diseases. These procedures rely on sophisticated angiographical imaging guidance, which encounters challenges because of limited contrast spatial resolution. Achieving a more precise visualization underlying arterial pathology neurovascular implants is crucial accurate procedural decision-making. In human study involving 32 patients, we introduced clinical application...
Background Digital subtraction angiography is the gold standard for detecting and characterising aneurysms. Here, we assess feasibility of commercial-grade deep learning software detection intracranial aneurysms on whole-brain anteroposterior lateral 2D digital images. Material methods Seven hundred six images were included from a cohort 240 patients (157 female, mean age 59 years, range 20–92; 83 male, 55 19–83). Three thirty-five (47%) single frame series 187 (41 ruptured, 146 unruptured;...
Super large-bore aspiration (SLBA) has shown high rates of complete clot ingestion.To report the initial clinical feasibility, safety, and efficacy this novel SLBA insert combination-super ingestion (SLIC) technique for stroke.We performed a retrospective review three comprehensive stroke center databases. The SLIC entails triaxial assembly an 8 Fr 0.106″ Base Camp catheter, 0.088″ catheter extender (HiPoint), (Tenzing 8) that completely consumes inner diameter catheter. HiPoint is delivered...
Background Direct aspiration thrombectomy techniques use large bore catheters for mechanical thrombectomy. Several are now available. We report a bench top exploration of novel beveled tip catheter and our experience in treating vessel occlusions (LVOs) using next-generation catheters. Methods A retrospective analysis from prospectively maintained database comparing the bevel shaped versus non-beveled was performed. Patient demographics, periprocedural metrics, discharge 90-day modified...
Abstract Cor triatriatum is a rare congenital cardiac malformation and it usually refers to the left atrium. We report an unusual case of cor in 33 - year old woman presented with congestive heart failure caused by ventricular systolic dysfunction.
We aimed to investigate the angular changes after Y-stenting of basilar bifurcation aneurysms.A total 19 patients (age range, 27-80 years; mean age, 52.5 years) underwent Y-stent coiling for aneurysm. Three vascular angles (α, β1, β2) were measured in anteroposterior plane. β1 and β2 represented between artery proximal P1 segments right left posterior cerebral arteries, respectively. α complementary angle angles. Angles before stent deployment. Diameters P2 segment at both sides. Correlation...
High-frequency optical coherence tomography (HF-OCT) is an intra-vascular imaging technique capable of assessing device-vessel interactions at spatial resolution approaching 10 µm. We tested the hypothesis that adequately deployed Woven EndoBridge (WEB) devices as visualized by HF-OCT lead to higher aneurysm occlusion rates.In a leporine model, elastase-induced aneurysms (n=24) were treated with WEB device. and digital subtraction angiography (DSA) performed following deployment repeated 4,...
Abstract Background Foramen of Morgagni hernias have traditionally been repaired by laparotomy, lapascopy or even thoracoscopy. However, the trans-sternal approach should be used when these rare coexist with other cardiac surgical diseases. Case presentation We present case a 74 year-old symptomatic male severe aortic valve stenosis and global respiratory failure due to giant hernia causing additionally tamponade. The patient underwent simultaneous repair defect replacement under...
Moyamoya disease is an idiopathic characterized by the progressive stenosis and collateral development of distal internal carotid arteries. In this disease, several vascular structures develop following occlusion. The ivy sign a characteristic Magnetic rezonance imaging (MRI) finding frequently encountered in patients with moyamoya. It can be observed both post contrast T1-weighted images Fluid attenuated inversion recovery (FLAIR) images. While manifests form contrasting on cortical...
The micro-architectonics of the subarachnoid space (SAS) remain partially understood and largely ignored, likely result inability to image these structures in vivo. We explored transvascular imaging with high-frequency optical coherence tomography (HF-OCT) interrogate SAS. In vivo HF-OCT was performed 10 dogs both posterior anterior cerebral circulations. conduit vessels used were basilar, spinal, middle arteries through which perivascular SAS imaged. probe introduced via a microcatheter...
High-frequency optical coherence tomography (HF-OCT) is an intravascular imaging method that allows for volumetric of flow diverters in vivo.To examine the hypothesis a threshold both volume and area communicating malapposition can be predictive early aneurysm occlusion.Fifty-two rabbits underwent elastase formation, followed by treatment with diverter. At time implant, HF-OCT was acquired to study rate degree malapposition. Treated aneurysms were allowed heal either 90 or 180 days...
Congenital heart diseases that cause obstruction of the right ventricular outflow tract are often difficult to diagnose. We report case a 49-year-old man who presented with long-standing shortness breath on exertion. Imaging revealed caused by double-chambered ventricle, and he was referred for surgical correction. This emphasizes both detailed perioperative evaluation is needed when diagnosing adults present manifestations congenital disease method successful correction resulted in symptom...
Abstract Primary intimal aortic sarcoma represents a very rare and highly lethal medical entity. Diagnosis is made either by embolic events caused the tumor or surrounding tissue symptoms such as pain. Herein we report an extremely case of 51-year-old man previously operated for ascending aneurysm, who presented with clinical radiological findings suggestive ruptured thoracoabdominal type IV aneurysm. The patient underwent radical resection aorta placement composite 4-branched graft....